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Role of AMP-activated protein kinase in adipose tissue metabolism and inflammation

Clinical science (1979), 2013-04, Vol.124 (8), p.491-507

2013

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The Na+/Glucose Cotransporter Inhibitor Canagliflozin Activates AMPK by Inhibiting Mitochondrial Function and Increasing Cellular AMP Levels

Diabetes (New York, N.Y.), 2016-09, Vol.65 (9), p.2784-2794

2016

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Exploiting the anti-inflammatory effects of AMP-activated protein kinase activation

Expert opinion on investigational drugs, 2012-08, Vol.21 (8), p.1155-1167

2012

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Metformin suppresses adipogenesis through both AMP-activated protein kinase (AMPK)-dependent and AMPK-independent mechanisms

Molecular and cellular endocrinology, 2017-01, Vol.440, p.57-68

2017

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Nutrient regulation of inflammatory signalling in obesity and vascular disease

Clinical science (1979), 2021-07, Vol.135 (13), p.1563-1590

2021

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Phosphorylation of Janus kinase 1 (JAK1) by AMP-activated protein kinase (AMPK) links energy sensing to anti-inflammatory signaling

Science signaling, 2016-11, Vol.9 (453), p.ra109

2016

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Activation of AMP-activated protein kinase rapidly suppresses multiple pro-inflammatory pathways in adipocytes including IL-1 receptor-associated kinase-4 phosphorylation

Molecular and cellular endocrinology, 2017-01, Vol.440, p.44-56

2017

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Protein kinase C phosphorylates AMP-activated protein kinase α1 Ser487

Biochemical journal, 2016-12, Vol.473 (24), p.4681-4697

2016

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Perivascular fat, AMP‐activated protein kinase and vascular diseases

British journal of pharmacology, 2014-02, Vol.171 (3), p.595-617

2014

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Molecular mechanisms regulating perivascular adipose tissue – potential pharmacological targets?

British journal of pharmacology, 2017-10, Vol.174 (20), p.3385-3387

2017

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5-aminoimidazole-4-carboxamide riboside mimics the effects of insulin on the expression of the 2 key gluconeogenic genes PEPCK and glucose-6-phosphatase

Diabetes (New York, N.Y.), 2000-06, Vol.49 (6), p.896-903

2000

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Direct Activation of AMP-activated Protein Kinase Stimulates Nitric-oxide Synthesis in Human Aortic Endothelial Cells

The Journal of biological chemistry, 2003-08, Vol.278 (34), p.31629-31639

2003

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Metformin action on AMP-activated protein kinase: a translational research approach to understanding a potential new therapeutic target

Diabetic medicine, 2010-10, Vol.27 (10), p.1097-1106

2010

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AMP-Activated Protein Kinase: An Ubiquitous Signaling Pathway With Key Roles in the Cardiovascular System

Circulation research, 2017-05, Vol.120 (11), p.1825-1841

2017

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Fat oxidation, fitness and skeletal muscle expression of oxidative/lipid metabolism genes in South Asians: implications for insulin resistance?

PloS one, 2010-12, Vol.5 (12), p.e14197-e14197

2010

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High Fat Diet Attenuates the Anticontractile Activity of Aortic PVAT via a Mechanism Involving AMPK and Reduced Adiponectin Secretion

Frontiers in physiology, 2018-02, Vol.9, p.51-51

2018

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A769662 Inhibits Insulin-Stimulated Akt Activation in Human Macrovascular Endothelial Cells Independent of AMP-Activated Protein Kinase

International journal of molecular sciences, 2018-12, Vol.19 (12), p.3886

2018

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Mitochondrial reactive oxygen species enhance AMP-activated protein kinase activation in the endothelium of patients with coronary artery disease and diabetes

Clinical science (1979), 2013-03, Vol.124 (6), p.403-411

2013

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AMP-activated protein kinase is activated in adipose tissue of individuals with type 2 diabetes treated with metformin: a randomised glycaemia-controlled crossover study

Diabetologia, 2011-07, Vol.54 (7), p.1799-1809

2011

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Regulation of nutrient uptake by AMP-activated protein kinase

Cellular signalling, 2020-12, Vol.76, p.109807-109807, Article 109807

2020

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Canagliflozin inhibits interleukin-1β-stimulated cytokine and chemokine secretion in vascular endothelial cells by AMP-activated protein kinase-dependent and -independent mechanisms

Scientific reports, 2018-03, Vol.8 (1), p.5276-14, Article 5276

2018

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AMP-activated protein kinase: an ultrasensitive system for monitoring cellular energy charge

Biochemical journal, 1999-03, Vol.338 ( Pt 3) (3), p.717-722

1999

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AMP-activated protein kinase (AMPK) as a potential therapeutic target independent of PI3K/Akt signaling in prostate cancer

Oncoscience, 2014-06, Vol.1 (6), p.446-456

2014

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AMP-activated protein kinase mediates VEGF-stimulated endothelial NO production

Biochemical and biophysical research communications, 2007-03, Vol.354 (4), p.1084-1088

2007

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Role of AMP-Activated Protein Kinase in the Regulation by Glucose of Islet Beta Cell Gene Expression

Proceedings of the National Academy of Sciences - PNAS, 2000-04, Vol.97 (8), p.4023-4028

2000

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Role of AMP-activated protein kinase in adipose tissue metabolism and inflammation

The Na+/Glucose Cotransporter Inhibitor Canagliflozin Activates AMPK by Inhibiting Mitochondrial Function and Increasing Cellular AMP Levels

Exploiting the anti-inflammatory effects of AMP-activated protein kinase activation

Metformin suppresses adipogenesis through both AMP-activated protein kinase (AMPK)-dependent and AMPK-independent mechanisms

Nutrient regulation of inflammatory signalling in obesity and vascular disease

Phosphorylation of Janus kinase 1 (JAK1) by AMP-activated protein kinase (AMPK) links energy sensing to anti-inflammatory signaling

Activation of AMP-activated protein kinase rapidly suppresses multiple pro-inflammatory pathways in adipocytes including IL-1 receptor-associated kinase-4 phosphorylation

Protein kinase C phosphorylates AMP-activated protein kinase α1 Ser487

Perivascular fat, AMP‐activated protein kinase and vascular diseases

Molecular mechanisms regulating perivascular adipose tissue – potential pharmacological targets?

5-aminoimidazole-4-carboxamide riboside mimics the effects of insulin on the expression of the 2 key gluconeogenic genes PEPCK and glucose-6-phosphatase

Direct Activation of AMP-activated Protein Kinase Stimulates Nitric-oxide Synthesis in Human Aortic Endothelial Cells

Metformin action on AMP-activated protein kinase: a translational research approach to understanding a potential new therapeutic target

AMP-Activated Protein Kinase: An Ubiquitous Signaling Pathway With Key Roles in the Cardiovascular System

Fat oxidation, fitness and skeletal muscle expression of oxidative/lipid metabolism genes in South Asians: implications for insulin resistance?

High Fat Diet Attenuates the Anticontractile Activity of Aortic PVAT via a Mechanism Involving AMPK and Reduced Adiponectin Secretion

A769662 Inhibits Insulin-Stimulated Akt Activation in Human Macrovascular Endothelial Cells Independent of AMP-Activated Protein Kinase

Mitochondrial reactive oxygen species enhance AMP-activated protein kinase activation in the endothelium of patients with coronary artery disease and diabetes

AMP-activated protein kinase is activated in adipose tissue of individuals with type 2 diabetes treated with metformin: a randomised glycaemia-controlled crossover study

Regulation of nutrient uptake by AMP-activated protein kinase

Canagliflozin inhibits interleukin-1β-stimulated cytokine and chemokine secretion in vascular endothelial cells by AMP-activated protein kinase-dependent and -independent mechanisms

AMP-activated protein kinase: an ultrasensitive system for monitoring cellular energy charge

AMP-activated protein kinase (AMPK) as a potential therapeutic target independent of PI3K/Akt signaling in prostate cancer

AMP-activated protein kinase mediates VEGF-stimulated endothelial NO production

Role of AMP-Activated Protein Kinase in the Regulation by Glucose of Islet Beta Cell Gene Expression

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