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Organic Cation Transporters in the Lung-Current and Emerging (Patho)Physiological and Pharmacological Concepts

International journal of molecular sciences, 2020-12, Vol.21 (23), p.9168

2020

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The Cell Line NCl-H441 Is a Useful in Vitro Model for Transport Studies of Human Distal Lung Epithelial Barrier

Molecular pharmaceutics, 2014-03, Vol.11 (3), p.995-1006

2014

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Bypassing CFTR dysfunction in cystic fibrosis with alternative pathways for anion transport

Current opinion in pharmacology, 2017-06, Vol.34, p.91-97

2017

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Chronic rhinosinusitis with nasal polyps is associated with impaired TMEM16A-mediated epithelial chloride secretion

Journal of allergy and clinical immunology, 2021-06, Vol.147 (6), p.2191-2201.e2

2021

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Generation and functional characterization of epithelial cells with stable expression of SLC26A9 Cl- channels

American journal of physiology. Lung cellular and molecular physiology, 2016-04, Vol.310 (7), p.L593-L602

2016

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Nanoparticles attenuate P-glycoprotein/MDR1 function in A549 human alveolar epithelial cells

European journal of pharmaceutics and biopharmaceutics, 2011-04, Vol.77 (3), p.392-397

2011

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Physicochemical and biopharmaceutical characterization of novel Matrix-Liposomes

European journal of pharmaceutics and biopharmaceutics, 2020-08, Vol.153, p.158-167

2020

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Expression and function of Anoctamin 1/TMEM16A calcium-activated chloride channels in airways of in vivo mouse models for cystic fibrosis research

Pflügers Archiv, 2018-09, Vol.470 (9), p.1335-1348

2018

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Transport of the fluorescent organic cation 4-(4-(dimethylamino)styryl)-N-methylpyridinium iodide (ASP+) in human respiratory epithelial cells

European journal of pharmaceutics and biopharmaceutics, 2012-06, Vol.81 (2), p.351-359

2012

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In Vitro and In Vivo Characterisation of PEG-Lipid-Based Micellar Complexes of Salmon Calcitonin for Pulmonary Delivery

Pharmaceutical research, 2012-06, Vol.29 (6), p.1425-1434

2012

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Beta‑2 Adrenergic Agonists Are Substrates and Inhibitors of Human Organic Cation Transporter 1

Molecular pharmaceutics, 2015-08, Vol.12 (8), p.2633-2641

2015

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Organic cation transporter function in different in vitro models of human lung epithelium

European journal of pharmaceutical sciences, 2015-12, Vol.80, p.82-88

2015

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OCTN2-Mediated Acetyl-l-Carnitine Transport in Human Pulmonary Epithelial Cells In Vitro

Pharmaceutics, 2019-08, Vol.11 (8), p.396

2019

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The Verapamil Transporter Expressed in Human Alveolar Epithelial Cells (A549) Does Not Interact with β2-Receptor Agonists

Drug metabolism and pharmacokinetics, 2014, Vol.29 (1), p.101-104

2014

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Increased Inflammatory Markers Detected in Nasal Lavage Correlate with Paranasal Sinus Abnormalities at MRI in Adolescent Patients with Cystic Fibrosis

Antioxidants, 2021-09, Vol.10 (9), p.1412

2021

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Organic cation transporters in the blood-air barrier: expression and implications for pulmonary drug delivery

Therapeutic delivery, 2012-06, Vol.3 (6), p.735-747

2012

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Cellular distribution and function of ion channels involved in transport processes in rat tracheal epithelium

Physiological reports, 2017-06, Vol.5 (12), p.e13290-n/a

2017

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Biopharmaceutical in vitro characterization of CPZEN-45, a drug candidate for inhalation therapy of tuberculosis

Therapeutic delivery, 2013-08, Vol.4 (8), p.915-923

2013

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New fluorescent bile acids: Synthesis, chemical characterization, and disastereoselective uptake by Caco-2 cells of 3-deoxy 3-NBD-amino deoxycholic and ursodeoxycholic acid

Bioorganic & medicinal chemistry, 2012-03, Vol.20 (5), p.1767-1778

2012

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Transport of organic cations across human bronchial and bronchiolar epithelial barriers in vitro

The FASEB journal, 2012-04, Vol.26 (S1)

2012

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µCT to quantify muco-obstructive lung disease and effects of neutrophil elastase knockout in mice

American journal of physiology. Lung cellular and molecular physiology, 2022-03, Vol.322 (3), p.L401-L411

2022

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Human bronchiolar epithelial cells functionally express P‐glycoprotein and multidrug resistance‐related protein‐1 (1064.11)

The FASEB journal, 2014-04, Vol.28 (S1), p.n/a

2014

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The Ca 2+ ‐Activated Chloride Channel TMEM16A Colocalizes with CFTR Chloride Channels in Rodent Secretory Airway Epithelial Cells

The FASEB journal, 2017-04, Vol.31 (S1)

2017

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Nanoparticles attenuate P‐glycoprotein function in A549 cells

The FASEB journal, 2010-04, Vol.24 (S1), p.758.1-758.1

2010

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OCTN1‐Mediated Ergothioneine Uptake Protects Lung Epithelial Cells From Tobacco Smoke‐Induced Damage

The FASEB journal, 2015-04, Vol.29 (S1)

2015

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Organic Cation Transporters in the Lung-Current and Emerging (Patho)Physiological and Pharmacological Concepts

The Cell Line NCl-H441 Is a Useful in Vitro Model for Transport Studies of Human Distal Lung Epithelial Barrier

Bypassing CFTR dysfunction in cystic fibrosis with alternative pathways for anion transport

Chronic rhinosinusitis with nasal polyps is associated with impaired TMEM16A-mediated epithelial chloride secretion

Generation and functional characterization of epithelial cells with stable expression of SLC26A9 Cl- channels

Nanoparticles attenuate P-glycoprotein/MDR1 function in A549 human alveolar epithelial cells

Physicochemical and biopharmaceutical characterization of novel Matrix-Liposomes

Expression and function of Anoctamin 1/TMEM16A calcium-activated chloride channels in airways of in vivo mouse models for cystic fibrosis research

Transport of the fluorescent organic cation 4-(4-(dimethylamino)styryl)-N-methylpyridinium iodide (ASP+) in human respiratory epithelial cells

In Vitro and In Vivo Characterisation of PEG-Lipid-Based Micellar Complexes of Salmon Calcitonin for Pulmonary Delivery

Beta‑2 Adrenergic Agonists Are Substrates and Inhibitors of Human Organic Cation Transporter 1

Organic cation transporter function in different in vitro models of human lung epithelium

OCTN2-Mediated Acetyl-l-Carnitine Transport in Human Pulmonary Epithelial Cells In Vitro

The Verapamil Transporter Expressed in Human Alveolar Epithelial Cells (A549) Does Not Interact with β2-Receptor Agonists

Increased Inflammatory Markers Detected in Nasal Lavage Correlate with Paranasal Sinus Abnormalities at MRI in Adolescent Patients with Cystic Fibrosis

Organic cation transporters in the blood-air barrier: expression and implications for pulmonary drug delivery

Cellular distribution and function of ion channels involved in transport processes in rat tracheal epithelium

Biopharmaceutical in vitro characterization of CPZEN-45, a drug candidate for inhalation therapy of tuberculosis

New fluorescent bile acids: Synthesis, chemical characterization, and disastereoselective uptake by Caco-2 cells of 3-deoxy 3-NBD-amino deoxycholic and ursodeoxycholic acid

Transport of organic cations across human bronchial and bronchiolar epithelial barriers in vitro

µCT to quantify muco-obstructive lung disease and effects of neutrophil elastase knockout in mice

Human bronchiolar epithelial cells functionally express P‐glycoprotein and multidrug resistance‐related protein‐1 (1064.11)

The Ca 2+ ‐Activated Chloride Channel TMEM16A Colocalizes with CFTR Chloride Channels in Rodent Secretory Airway Epithelial Cells

Nanoparticles attenuate P‐glycoprotein function in A549 cells

OCTN1‐Mediated Ergothioneine Uptake Protects Lung Epithelial Cells From Tobacco Smoke‐Induced Damage

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