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Preparation of 3,5-Methanobenzo[b]azepines: An sp3‑Rich Quinolone Isostere

Organic letters, 2023-08, Vol.25 (33), p.6161-6166

2023

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Accelerating fragment-based library generation by coupling high-performance photoreactors with benchtop analysis

Beilstein journal of organic chemistry, 2020-05, Vol.16 (1), p.982-988

2020

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Activating Pyrimidines by Pre-distortion for the General Synthesis of 7‑Aza-indazoles from 2‑Hydrazonylpyrimidines via Intramolecular Diels–Alder Reactions

Journal of the American Chemical Society, 2019-10, Vol.141 (40), p.15901-15909

2019

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Domino Pd0‐Catalyzed C(sp3)–H Arylation/Electrocyclic Reactions via Benzazetidine Intermediates

Angewandte Chemie International Edition, 2018-09, Vol.57 (37), p.12131-12135

International ed. in English, 2018

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Pushing the Frontiers of Accessible Chemical Space to Unleash Design Creativity and Accelerate Drug Discovery

Chimia, 2020-10, Vol.74 (10), p.803

2020

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Synthesis and Anticonvulsant Activities of (R)-N-(4′-Substituted)benzyl 2-Acetamido-3-methoxypropionamides

Journal of medicinal chemistry, 2010-02, Vol.53 (3), p.1288-1305

2010

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d-Glucose: An Efficient Reducing Agent for a Copper(II)-Mediated Arylation of Primary Amines in Water

ChemSusChem, 2016-11, Vol.9 (22), p.3244-3249

2016

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Primary Amino Acid Derivatives: Compounds with Anticonvulsant and Neuropathic Pain Protection Activities

Journal of medicinal chemistry, 2011-07, Vol.54 (13), p.4815-4830

2011

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The Structure−Activity Relationship of the 3-Oxy Site in the Anticonvulsant (R)-N-Benzyl 2-Acetamido-3-methoxypropionamide

Journal of medicinal chemistry, 2010-08, Vol.53 (15), p.5716-5726

2010

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Merging the Structural Motifs of Functionalized Amino Acids and α-Aminoamides: Compounds with Significant Anticonvulsant Activities

Journal of medicinal chemistry, 2010-05, Vol.53 (9), p.3756-3771

2010

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Efficient and Mild Ullmann‐Type N‐Arylation of Amides, Carbamates, and Azoles in Water

Chemistry : a European journal, 2017-10, Vol.23 (55), p.13676-13683

2017

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Primary Amino Acid Derivatives: Substitution of the 4′-N′-Benzylamide Site in (R)-N′-Benzyl 2-Amino-3-methylbutanamide, (R)-N′-Benzyl 2-Amino-3,3-dimethylbutanamide, and (R)-N′-Benzyl 2-Amino-3-methoxypropionamide Provides Potent Anticonvulsants with Pain-Attenuating Properties

Journal of medicinal chemistry, 2011-10, Vol.54 (19), p.6417-6431

2011

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Preparation of new bicyclo[2.1.1]hexane compact modules: an opening towards novel sp-rich chemical space

Organic & biomolecular chemistry, 2022-11, Vol.2 (46), p.918-9111

2022

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Lacosamide Isothiocyanate-Based Agents: Novel Agents To Target and Identify Lacosamide Receptors

Journal of medicinal chemistry, 2009-11, Vol.52 (21), p.6897-6911

2009

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Development and Characterization of Novel Derivatives of the Antiepileptic Drug Lacosamide That Exhibit Far Greater Enhancement in Slow Inactivation of Voltage-Gated Sodium Channels

ACS chemical neuroscience, 2011-02, Vol.2 (2), p.90-106

2011

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Merging Structural Motifs of Functionalized Amino Acids and α-Aminoamides Results in Novel Anticonvulsant Compounds with Significant Effects on Slow and Fast Inactivation of Voltage-Gated Sodium Channels and in the Treatment of Neuropathic Pain

ACS chemical neuroscience, 2011-06, Vol.2 (6), p.317-332

2011

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On water N-arylation of oxetanylamines for the preparation of N-aryl-oxetanylamines; potentially useful aryl-amide isosteres

Chemical communications (Cambridge, England), 2019-01, Vol.55 (11), p.1623-1626

2019

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Domino Pd0‐Catalyzed C(sp3)–H Arylation/Electrocyclic Reactions via Benzazetidine Intermediates

Angewandte Chemie, 2018-09, Vol.130 (37), p.12307-12311

2018

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Preparation of 3,5-Methanobenzo[ b ]azepines: An sp 3 -Rich Quinolone Isostere

Organic letters, 2023-08, Vol.25 (33), p.6161-6166

2023

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Preparation of new bicyclo[2.1.1]hexane compact modules: an opening towards novel sp 3 -rich chemical space

Organic & biomolecular chemistry, 2022-11, Vol.20 (46), p.9108-9111

2022

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Preparation of new bicyclo[2.1.1]hexane compact modules: an opening towards novel sp3-rich chemical space

Organic & biomolecular chemistry, 2022-11, Vol.20 (46), p.9108-9111

2022

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Buchwald–Hartwig reactions in water using surfactants

Tetrahedron, 2014-05, Vol.70 (21), p.3413-3421

2014

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Identification of the Benzyloxyphenyl Pharmacophore: A Structural Unit That Promotes Sodium Channel Slow Inactivation

ACS chemical neuroscience, 2012-12, Vol.3 (12), p.1037-1049

2012

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t-BuXPhos: a highly efficient ligand for Buchwald–Hartwig coupling in water

Green chemistry : an international journal and green chemistry resource : GC, 2014, Vol.16 (9), p.4170-4178

2014

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Preparation of 3,5-Methanobenzo[b]azepines: An sp3‑Rich Quinolone Isostere

Accelerating fragment-based library generation by coupling high-performance photoreactors with benchtop analysis

Activating Pyrimidines by Pre-distortion for the General Synthesis of 7‑Aza-indazoles from 2‑Hydrazonylpyrimidines via Intramolecular Diels–Alder Reactions

Domino Pd0‐Catalyzed C(sp3)–H Arylation/Electrocyclic Reactions via Benzazetidine Intermediates

Pushing the Frontiers of Accessible Chemical Space to Unleash Design Creativity and Accelerate Drug Discovery

Synthesis and Anticonvulsant Activities of (R)-N-(4′-Substituted)benzyl 2-Acetamido-3-methoxypropionamides

d-Glucose: An Efficient Reducing Agent for a Copper(II)-Mediated Arylation of Primary Amines in Water

Primary Amino Acid Derivatives: Compounds with Anticonvulsant and Neuropathic Pain Protection Activities

The Structure−Activity Relationship of the 3-Oxy Site in the Anticonvulsant (R)-N-Benzyl 2-Acetamido-3-methoxypropionamide

Merging the Structural Motifs of Functionalized Amino Acids and α-Aminoamides: Compounds with Significant Anticonvulsant Activities

Chemical Library Screening and Structure-Function Relationship Studies Identify Bisacodyl as a Potent and Selective Cytotoxic Agent Towards Quiescent Human Glioblastoma Tumor Stem-Like Cells

Efficient and Mild Ullmann‐Type N‐Arylation of Amides, Carbamates, and Azoles in Water

Primary Amino Acid Derivatives: Substitution of the 4′-N′-Benzylamide Site in (R)-N′-Benzyl 2-Amino-3-methylbutanamide, (R)-N′-Benzyl 2-Amino-3,3-dimethylbutanamide, and (R)-N′-Benzyl 2-Amino-3-methoxypropionamide Provides Potent Anticonvulsants with Pain-Attenuating Properties

Preparation of new bicyclo[2.1.1]hexane compact modules: an opening towards novel sp-rich chemical space

Lacosamide Isothiocyanate-Based Agents: Novel Agents To Target and Identify Lacosamide Receptors

Development and Characterization of Novel Derivatives of the Antiepileptic Drug Lacosamide That Exhibit Far Greater Enhancement in Slow Inactivation of Voltage-Gated Sodium Channels

Merging Structural Motifs of Functionalized Amino Acids and α-Aminoamides Results in Novel Anticonvulsant Compounds with Significant Effects on Slow and Fast Inactivation of Voltage-Gated Sodium Channels and in the Treatment of Neuropathic Pain

On water N-arylation of oxetanylamines for the preparation of N-aryl-oxetanylamines; potentially useful aryl-amide isosteres

Domino Pd0‐Catalyzed C(sp3)–H Arylation/Electrocyclic Reactions via Benzazetidine Intermediates

Preparation of 3,5-Methanobenzo[ b ]azepines: An sp 3 -Rich Quinolone Isostere

Preparation of new bicyclo[2.1.1]hexane compact modules: an opening towards novel sp 3 -rich chemical space

Preparation of new bicyclo[2.1.1]hexane compact modules: an opening towards novel sp3-rich chemical space

Buchwald–Hartwig reactions in water using surfactants

Identification of the Benzyloxyphenyl Pharmacophore: A Structural Unit That Promotes Sodium Channel Slow Inactivation

t-BuXPhos: a highly efficient ligand for Buchwald–Hartwig coupling in water

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