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Glutathione S-transferase copy number variation alters lung gene expression

The European respiratory journal, 2011-07, Vol.38 (1), p.15-28

2011

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Low-pass genome-wide sequencing and variant inference using identity-by-descent in an isolated human population

Genetics (Austin), 2012-02, Vol.190 (2), p.679-689

2012

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C74 ADVANCES IN TRANSLATIONAL COPD: Anatomic Gradients, Cell Specificity And Smoking Modulation Of Human Airway Epithelium Expression Of Adh7, The Rate Limiting Enzyme For Generation Of Retinoic Acid

American journal of respiratory and critical care medicine, 2017-01, Vol.195

2017

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A73 BEYOND CIGARETTE SMOKE IN COPD: Airway Basal Cells Expressed Transforming Growth Factor-á (tgfa) As A Modulator Of Smoking-Induced Airway Remodeling

American journal of respiratory and critical care medicine, 2017-01, Vol.195

2017

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A71 ONCOGENES AND ANGIOGENESIS IN LUNG TUMORS: Function Of Kras In Regulating Differentiation Of Normal Human Airway Basal Cells Into A Mucociliated Epithelium

American journal of respiratory and critical care medicine, 2017-01, Vol.195

2017

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C73 NEW MECHANISMS AND THERAPIES IN COPD: Function Of Lypd2 (ly6/pla Ur Domain Category 2) In Maintaining Normal Airway Differentiation

American journal of respiratory and critical care medicine, 2017-01, Vol.195

2017

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C34 MECHANISMS OF HOST DEFENSE IN BACTERIAL AND FUNGAL INFECTIONS: Human Hiv1-Infection Is Associated With Reprogramming Of Alveolar Macrophages Despite Systemic Control Of Infection With Anti-Retroviral Therapy

American journal of respiratory and critical care medicine, 2017-01, Vol.195

2017

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D44 FIRST LINE OF DEFENSE: AIRWAY RESPONSE TO INFECTIONS AND IRRITANTS: "memory Of Smoking": Persistent Dysregulation Of Expression Of A Subset Of Smoking-Related Genes In The Small Airway Epithelium And Alveolar Macrophages Following Cessation

American journal of respiratory and critical care medicine, 2015-01, Vol.191, p.1

2015

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C25 HIV-ASSOCIATED LUNG INFECTIONS/DISORDERS - FROM BASIC TO CLINICAL: Up-Regulation Of Human Alveolar Macrophage Prostaglandin E Synthase Gene Expression By Hiv1 Infection

American journal of respiratory and critical care medicine, 2016-01, Vol.193, p.1

2016

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D96 DAMAGING EFFECTS OF INHALED PARTICULATES: Acute Exposure To Electronic Cigarettes In Healthy Nonsmokers Leads To Global Transcriptome Changes In Distal Airway Epithelium And Alveolar Macrophages

American journal of respiratory and critical care medicine, 2016-01, Vol.193, p.1

2016

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C71 YOU ARE WHAT YOU BREATHE: AIRWAY CELL BIOLOGY IN COPD: Smoking-Induced Up-Regulation Of Klf4 Modulates Partial Somatic Cell- Reprogramming-Like In The Human Airway Epithelium

American journal of respiratory and critical care medicine, 2016-01, Vol.193, p.1

2016

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A72 MECHANISMS OF LUNG CANCER BIOLOGY: Suppression Of Kras Expression In Normal Airway Basal Cells Shifts Differentiation To A Squamous/emt Phenotype

American journal of respiratory and critical care medicine, 2016-01, Vol.193, p.1

2016

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A27 HIV AND THE LUNG: Smoking-Induced Disordered Reprogramming Of Gene Expression In Human Alveolar Macrophages From Hiv1+ Individuals

American journal of respiratory and critical care medicine, 2014-01, Vol.189, p.1

2014

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C55 HIV-ASSOCIATED LUNG DISEASES AND INFECTIONS: Hiv And Smoking-Dependent Reprogramming Of The Small Airway Transcriptome

American journal of respiratory and critical care medicine, 2015-01, Vol.191, p.1

2015

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C13 TRANSLATIONAL RESEARCH IN ASTHMA: Characterization Of "th2 Low" Asthmatic Endotype

American journal of respiratory and critical care medicine, 2017-01, Vol.195

2017

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A71 EPIGENETICS: Light-Use Waterpipe (shisha) Smoking Induces Epigenetic Changes In The Small Airway Epithelium

American journal of respiratory and critical care medicine, 2016-01, Vol.193, p.1

2016

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A19 PATHOLOGIC PROGRAMMING OF AIRWAY EPITHELIUM: Distal-To-Proximal Remodeling Of Small Airway Epithelium In Smokers Mediated By Egf Signaling In Small Airway Basal Progenitor Cells

American journal of respiratory and critical care medicine, 2015-01, Vol.191, p.1

2015

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A110 LATE BREAKING ABSTRACTS IN DISEASE SUSCEPTIBILITY AND PATHOGENESIS: Smoking-Induced Alternative Splicing Of Transcript Variants In Human Airway Basal Cells At COPD Risk Locus 19q13.2

American journal of respiratory and critical care medicine, 2014-01, Vol.189, p.1

2014

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D31 NOVEL MECHANISMS OF ALLERGY AND AIRWAY INFLAMMATION: Low Ige And Eosinophils Allergic Asthma Is Characterized By Altered Levels Of Circulating Apoptotic Endothelial Microparticles

American journal of respiratory and critical care medicine, 2016-01, Vol.193, p.1

2016

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D27 MITOCHONDRIA: LIVE AND LET DIE: Up-Regulation Of Osgin1 Provides A Link Between Smoking-Induced Stress And Autophagy In The Human Airway Epithelium

American journal of respiratory and critical care medicine, 2015-01, Vol.191, p.1

2015

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Increased power of mixed models facilitates association mapping of 10 loci for metabolic traits in an isolated population

Human molecular genetics, 2011-02, Vol.20 (4), p.827-839

2011

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Linkage Analysis of Quantitative Traits for Obesity, Diabetes, Hypertension, and Dyslipidemia on the Island of Kosrae, Federated States of Micronesia

Proceedings of the National Academy of Sciences - PNAS, 2006-03, Vol.103 (10), p.3502-3509

2006

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A19 PATHOLOGIC PROGRAMMING OF AIRWAY EPITHELIUM: Bmp4 Signaling In Airway Basal Stem/progenitor Cells Induces COPD-Relevant Airway Epithelial Phenotypes

American journal of respiratory and critical care medicine, 2015-01, Vol.191, p.1

2015

Volltextzugriff (PDF)

C21 APPLYING 'OMICS TECHNOLOGIES TO REVEAL GENE REGULATORS AND BIOMARKERS IN LUNG DEVELOPMENT AND DISEASE: Precision Transcriptomes: Among A Population Of Healthy Smokers, What Are The Shared Vs Individual Smoking-Responsive Genes In The Small Airway Epithelium And Alveolar Macrophages?

American journal of respiratory and critical care medicine, 2016-01, Vol.193, p.1

2016

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Evaluating potential for whole-genome studies in Kosrae, an isolated population in Micronesia

Nature genetics, 2006-02, Vol.38 (2), p.214-217

2006

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Glutathione S-transferase copy number variation alters lung gene expression

Low-pass genome-wide sequencing and variant inference using identity-by-descent in an isolated human population

C74 ADVANCES IN TRANSLATIONAL COPD: Anatomic Gradients, Cell Specificity And Smoking Modulation Of Human Airway Epithelium Expression Of Adh7, The Rate Limiting Enzyme For Generation Of Retinoic Acid

A73 BEYOND CIGARETTE SMOKE IN COPD: Airway Basal Cells Expressed Transforming Growth Factor-á (tgfa) As A Modulator Of Smoking-Induced Airway Remodeling

A71 ONCOGENES AND ANGIOGENESIS IN LUNG TUMORS: Function Of Kras In Regulating Differentiation Of Normal Human Airway Basal Cells Into A Mucociliated Epithelium

C73 NEW MECHANISMS AND THERAPIES IN COPD: Function Of Lypd2 (ly6/pla Ur Domain Category 2) In Maintaining Normal Airway Differentiation

C34 MECHANISMS OF HOST DEFENSE IN BACTERIAL AND FUNGAL INFECTIONS: Human Hiv1-Infection Is Associated With Reprogramming Of Alveolar Macrophages Despite Systemic Control Of Infection With Anti-Retroviral Therapy

D44 FIRST LINE OF DEFENSE: AIRWAY RESPONSE TO INFECTIONS AND IRRITANTS: "memory Of Smoking": Persistent Dysregulation Of Expression Of A Subset Of Smoking-Related Genes In The Small Airway Epithelium And Alveolar Macrophages Following Cessation

C25 HIV-ASSOCIATED LUNG INFECTIONS/DISORDERS - FROM BASIC TO CLINICAL: Up-Regulation Of Human Alveolar Macrophage Prostaglandin E Synthase Gene Expression By Hiv1 Infection

D96 DAMAGING EFFECTS OF INHALED PARTICULATES: Acute Exposure To Electronic Cigarettes In Healthy Nonsmokers Leads To Global Transcriptome Changes In Distal Airway Epithelium And Alveolar Macrophages

C71 YOU ARE WHAT YOU BREATHE: AIRWAY CELL BIOLOGY IN COPD: Smoking-Induced Up-Regulation Of Klf4 Modulates Partial Somatic Cell- Reprogramming-Like In The Human Airway Epithelium

A72 MECHANISMS OF LUNG CANCER BIOLOGY: Suppression Of Kras Expression In Normal Airway Basal Cells Shifts Differentiation To A Squamous/emt Phenotype

A27 HIV AND THE LUNG: Smoking-Induced Disordered Reprogramming Of Gene Expression In Human Alveolar Macrophages From Hiv1+ Individuals

C55 HIV-ASSOCIATED LUNG DISEASES AND INFECTIONS: Hiv And Smoking-Dependent Reprogramming Of The Small Airway Transcriptome

C13 TRANSLATIONAL RESEARCH IN ASTHMA: Characterization Of "th2 Low" Asthmatic Endotype

A71 EPIGENETICS: Light-Use Waterpipe (shisha) Smoking Induces Epigenetic Changes In The Small Airway Epithelium

A19 PATHOLOGIC PROGRAMMING OF AIRWAY EPITHELIUM: Distal-To-Proximal Remodeling Of Small Airway Epithelium In Smokers Mediated By Egf Signaling In Small Airway Basal Progenitor Cells

A110 LATE BREAKING ABSTRACTS IN DISEASE SUSCEPTIBILITY AND PATHOGENESIS: Smoking-Induced Alternative Splicing Of Transcript Variants In Human Airway Basal Cells At COPD Risk Locus 19q13.2

D31 NOVEL MECHANISMS OF ALLERGY AND AIRWAY INFLAMMATION: Low Ige And Eosinophils Allergic Asthma Is Characterized By Altered Levels Of Circulating Apoptotic Endothelial Microparticles

D27 MITOCHONDRIA: LIVE AND LET DIE: Up-Regulation Of Osgin1 Provides A Link Between Smoking-Induced Stress And Autophagy In The Human Airway Epithelium

Increased power of mixed models facilitates association mapping of 10 loci for metabolic traits in an isolated population

Linkage Analysis of Quantitative Traits for Obesity, Diabetes, Hypertension, and Dyslipidemia on the Island of Kosrae, Federated States of Micronesia

A19 PATHOLOGIC PROGRAMMING OF AIRWAY EPITHELIUM: Bmp4 Signaling In Airway Basal Stem/progenitor Cells Induces COPD-Relevant Airway Epithelial Phenotypes

C21 APPLYING 'OMICS TECHNOLOGIES TO REVEAL GENE REGULATORS AND BIOMARKERS IN LUNG DEVELOPMENT AND DISEASE: Precision Transcriptomes: Among A Population Of Healthy Smokers, What Are The Shared Vs Individual Smoking-Responsive Genes In The Small Airway Epithelium And Alveolar Macrophages?

Evaluating potential for whole-genome studies in Kosrae, an isolated population in Micronesia

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