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A bispecific antibody targeting sclerostin and DKK-1 promotes bone mass accrual and fracture repair

Nature communications, 2016-05, Vol.7 (1), p.11505-11505, Article 11505

2016

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Late-life targeting of the IGF-1 receptor improves healthspan and lifespan in female mice

Nature communications, 2018-06, Vol.9 (1), p.2394-12, Article 2394

2018

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Rapid single B cell antibody discovery using nanopens and structured light

mAbs, 2019-08, Vol.11 (6), p.1025-1035

2019

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A fully human anti-hepcidin antibody modulates iron metabolism in both mice and nonhuman primates

Blood, 2013-10, Vol.122 (17), p.3054-3061

2013

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Pharmacokinetic comparison of a diverse panel of non-targeting human antibodies as matched IgG1 and IgG2 isotypes in rodents and non-human primates

PloS one, 2019-05, Vol.14 (5), p.e0217061

2019

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An In vivo Platform for Translational Drug Development in Pancreatic Cancer

Clinical cancer research, 2006-08, Vol.12 (15), p.4652-4661

2006

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Dickkopf‐1 regulates bone formation in young growing rodents and upon traumatic injury

Journal of bone and mineral research, 2011-11, Vol.26 (11), p.2610-2621

2011

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Simultaneous Analysis of Multiple Monoclonal Antibody Biotherapeutics by LC-MS/MS Method in Rat Plasma Following Cassette-Dosing

The AAPS journal, 2013-04, Vol.15 (2), p.337-346

2013

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A multireflection cell for enhanced absorbance detection in microchip-based capillary electrophoresis devices

Electrophoresis, 2000-04, Vol.21 (7), p.1291-1299

2000

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Protein separation and surfactant control of electroosmotic flow in poly(dimethylsiloxane)-coated capillaries and microchips

Journal of Chromatography A, 2002-02, Vol.947 (2), p.277-286

2002

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Electroosmotic Pumping of Organic Solvents and Reagents in Microfabricated Reactor Chips

Journal of the American Chemical Society, 1997-09, Vol.119 (37), p.8716-8717

1997

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A Non-radiometric Approach to Determine Tissue Vascular Blood Volume in Biodistribution Studies

The AAPS journal, 2022-11, Vol.24 (6), p.116, Article 116

2022

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Application of Nonaqueous Capillary Electrophoresis to the Separation of Long-Chain Surfactants

Analytical chemistry (Washington), 1996-01, Vol.68 (2), p.293-299

1996

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Capillary Electrophoresis of Inorganic Anions in Nonaqueous Media with Electrochemical and Indirect UV Detection

Analytical chemistry (Washington), 1995-03, Vol.67 (6), p.1067-1073

1995

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Control of separation selectivity and electroosmotic flow in nonaqueous capillary electrophoretic separations of alkali and alkaline earth metal ions

Journal of Chromatography A, 1996-10, Vol.749 (1), p.279-286

1996

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Differential Enzyme-Linked Immunosorbent Assay and Ligand-Binding Mass Spectrometry for Analysis of Biotransformation of Protein Therapeutics: Application to Various FGF21 Modalities

Analytical chemistry (Washington), 2013-03, Vol.85 (5), p.2731-2738

2013

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General LC-MS/MS Method Approach to Quantify Therapeutic Monoclonal Antibodies Using a Common Whole Antibody Internal Standard with Application to Preclinical Studies

Analytical chemistry (Washington), 2012-02, Vol.84 (3), p.1267-1273

2012

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Selectivity control in the non-aqueous capillary electrophoretic separation of amino acids

Journal of Chromatography A, 1997-11, Vol.790 (1), p.185-193

1997

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Bioanalytical Approaches to Quantify “Total” and “Free” Therapeutic Antibodies and Their Targets: Technical Challenges and PK/PD Applications Over the Course of Drug Development

The AAPS journal, 2011-03, Vol.13 (1), p.99-110

2011

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Evaluating the impact of matrix effects on biomarker assay sensitivity

Bioanalysis, 2014-04, Vol.6 (8), p.1081-1091

2014

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Engineering an IgG Scaffold Lacking Effector Function with Optimized Developability

The Journal of biological chemistry, 2017-02, Vol.292 (5), p.1865-1875

2017

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The serum protein transthyretin as a platform for dimerization and tetramerization of antibodies and Fab fragments to enable target clustering

The Journal of biological chemistry, 2020-07, Vol.295 (30), p.10446-10455

2020

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Development of an immunoassay for aglycosylated murine IgG1 in mouse serum via generation of a specific tool antibody

Bioanalysis, 2022-05, Vol.14 (9), p.581-588

2022

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Rapid affinity measurement of protein–protein interactions in a microfluidic platform

Analytical biochemistry, 2012-07, Vol.426 (2), p.134-141

2012

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Universal Immunoassay Applied During Early Development of Large Molecules to Understand Impact of Immunogenicity on Biotherapeutic Exposure

The AAPS journal, 2012-12, Vol.14 (4), p.843-849

2012

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A bispecific antibody targeting sclerostin and DKK-1 promotes bone mass accrual and fracture repair

Late-life targeting of the IGF-1 receptor improves healthspan and lifespan in female mice

Rapid single B cell antibody discovery using nanopens and structured light

A fully human anti-hepcidin antibody modulates iron metabolism in both mice and nonhuman primates

Pharmacokinetic comparison of a diverse panel of non-targeting human antibodies as matched IgG1 and IgG2 isotypes in rodents and non-human primates

An In vivo Platform for Translational Drug Development in Pancreatic Cancer

Dickkopf‐1 regulates bone formation in young growing rodents and upon traumatic injury

Simultaneous Analysis of Multiple Monoclonal Antibody Biotherapeutics by LC-MS/MS Method in Rat Plasma Following Cassette-Dosing

A multireflection cell for enhanced absorbance detection in microchip-based capillary electrophoresis devices

Protein separation and surfactant control of electroosmotic flow in poly(dimethylsiloxane)-coated capillaries and microchips

Electroosmotic Pumping of Organic Solvents and Reagents in Microfabricated Reactor Chips

A Non-radiometric Approach to Determine Tissue Vascular Blood Volume in Biodistribution Studies

Application of Nonaqueous Capillary Electrophoresis to the Separation of Long-Chain Surfactants

Capillary Electrophoresis of Inorganic Anions in Nonaqueous Media with Electrochemical and Indirect UV Detection

Control of separation selectivity and electroosmotic flow in nonaqueous capillary electrophoretic separations of alkali and alkaline earth metal ions

Differential Enzyme-Linked Immunosorbent Assay and Ligand-Binding Mass Spectrometry for Analysis of Biotransformation of Protein Therapeutics: Application to Various FGF21 Modalities

General LC-MS/MS Method Approach to Quantify Therapeutic Monoclonal Antibodies Using a Common Whole Antibody Internal Standard with Application to Preclinical Studies

Selectivity control in the non-aqueous capillary electrophoretic separation of amino acids

Bioanalytical Approaches to Quantify “Total” and “Free” Therapeutic Antibodies and Their Targets: Technical Challenges and PK/PD Applications Over the Course of Drug Development

Evaluating the impact of matrix effects on biomarker assay sensitivity

Engineering an IgG Scaffold Lacking Effector Function with Optimized Developability

The serum protein transthyretin as a platform for dimerization and tetramerization of antibodies and Fab fragments to enable target clustering

Development of an immunoassay for aglycosylated murine IgG1 in mouse serum via generation of a specific tool antibody

Rapid affinity measurement of protein–protein interactions in a microfluidic platform

Universal Immunoassay Applied During Early Development of Large Molecules to Understand Impact of Immunogenicity on Biotherapeutic Exposure

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