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An Fc-inert PD-L1×4-1BB bispecific antibody mediates potent anti-tumor immunity in mice by combining checkpoint inhibition and conditional 4-1BB co-stimulation

Oncoimmunology, 2022, Vol.11 (1), p.2030135-2030135

2022

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Integrated Pharmacokinetic/Pharmacodynamic Analysis for Determining the Minimal Anticipated Biological Effect Level of a Novel Anti-CD28 Receptor Antagonist BMS-931699

The Journal of pharmacology and experimental therapeutics, 2015-12, Vol.355 (3), p.506-515

2015

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Preclinical Characterization and Phase I Trial Results of a Bispecific Antibody Targeting PD-L1 and 4-1BB (GEN1046) in Patients with Advanced Refractory Solid Tumors

Cancer discovery, 2022-05, Vol.12 (5), p.1248-1265

2022

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Cytokines: The Good, the Bad, and the Deadly

International journal of toxicology, 2015-07, Vol.34 (4), p.355-365

2015

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DcR3/TR6 Effectively Prevents Islet Primary Nonfunction After Transplantation

Diabetes (New York, N.Y.), 2003-09, Vol.52 (9), p.2279-2286

2003

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A rugged and accurate liquid chromatography–tandem mass spectrometry method for quantitative determination of BMS-790052 in plasma

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2011-07, Vol.879 (22), p.2064-2072

2011

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d-α-tocopheryl polyethylene glycol 1000 succinate-containing vehicles provide no detectable chemoprotection from oxidative damage

Journal of applied toxicology, 2015-07, Vol.35 (7), p.791-798

2015

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Mouse T cells receive costimulatory signals from LIGHT, a TNF family member

Blood, 2002-11, Vol.100 (9), p.3279-3286

2002

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Incisor Degeneration in Rats Induced by Vascular Endothelial Growth Factor/Fibroblast Growth Factor Receptor Tyrosine Kinase Inhibition

Toxicologic pathology, 2010-02, Vol.38 (2), p.267-279

2010

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Novel Semi-Mechanistic Model Leveraging Preclinical and Clinical Data to Inform the Recommended Phase 2 Dose (RP2D) Selection for Epcoritamab (DuoBody CD3xCD20)

Blood, 2020-11, Vol.136 (Supplement 1), p.35-36

2020

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In vivo inhibition of Fas ligand-mediated killing by TR6, a Fas ligand decoy receptor

The Journal of pharmacology and experimental therapeutics, 2001-07, Vol.298 (1), p.25

2001

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Duobody-CD3xCD20 Shows Unique and Potent Preclinical Anti-Tumor Activity in Vitro and In Vivo, and Is Being Evaluated Clinically in Patients with B-Cell Malignancies

Blood, 2018-11, Vol.132 (Supplement 1), p.1664-1664

2018

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d-[alpha]-tocopheryl polyethylene glycol 1000 succinate-containing vehicles provide no detectable chemoprotection from oxidative damage

Journal of applied toxicology, 2015-07, Vol.35 (7), p.791

2015

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Effect of trifluoromethyl ketone-based elastase inhibitors on neutrophil function in vitro

Journal of leukocyte biology, 1998-09, Vol.64 (3), p.322-330

1998

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Modulation of T-cell responses to alloantigens by TR6/DcR3

The Journal of clinical investigation, 2001-06, Vol.107 (11), p.1459-1468

2001

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C-C chemokine receptor 3 antagonism by the beta-chemokine macrophage inflammatory protein 4, a property strongly enhanced by an amino-terminal alanine-methionine swap

The Journal of immunology (1950), 2000-02, Vol.164 (3), p.1488-1497

2000

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BLyS BINDS TO B CELLS WITH HIGH AFFINITY AND INDUCES ACTIVATION OF THE TRANSCRIPTION FACTORS NF-κB AND ELF-1

Cytokine (Philadelphia, Pa.), 2001-01, Vol.13 (1), p.25-31

2001

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Orally Active Trifluoromethyl Ketone Inhibitors of Human Leukocyte Elastase

Journal of medicinal chemistry, 1997-09, Vol.40 (20), p.3173-3181

1997

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ANALYSIS OF EOSINOPHILS AND MYELOID PROGENITOR RESPONSES TO MODIFIED FORMS OF MPIF-2

Cytokine (Philadelphia, Pa.), 2001-02, Vol.13 (4), p.209-219

2001

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Detection of tumor necrosis factor induced nuclear damage with p-phenylenediamine

Journal of immunological methods, 1992, Vol.148 (1), p.209-216

1992

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C-C Chemokine Receptor 3 Antagonism by the {beta}-Chemokine Macrophage Inflammatory Protein 4, a Property Strongly Enhanced by an Amino-Terminal Alanine-Methionine Swap

The Journal of immunology (1950), 2000-02, Vol.164 (3), p.1488

2000

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DuoBody-CD3xCD20 induces potent T-cell-mediated killing of malignant B cells in preclinical models and provides opportunities for subcutaneous dosing

EBioMedicine, 2020-02, Vol.52, p.102625, Article 102625

2020

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Tumor Rejection and Immune Memory Elicited by Locally Released LEC Chemokine Are Associated with an Impressive Recruitment of APCs, Lymphocytes, and Granulocytes

The Journal of immunology (1950), 2000-03, Vol.164 (6), p.3200-3206

2000

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An Fc-inert PD-L1×4-1BB bispecific antibody mediates potent anti-tumor immunity in mice by combining checkpoint inhibition and conditional 4-1BB co-stimulation

Integrated Pharmacokinetic/Pharmacodynamic Analysis for Determining the Minimal Anticipated Biological Effect Level of a Novel Anti-CD28 Receptor Antagonist BMS-931699

Preclinical Characterization and Phase I Trial Results of a Bispecific Antibody Targeting PD-L1 and 4-1BB (GEN1046) in Patients with Advanced Refractory Solid Tumors

Cytokines: The Good, the Bad, and the Deadly

DcR3/TR6 Effectively Prevents Islet Primary Nonfunction After Transplantation

A rugged and accurate liquid chromatography–tandem mass spectrometry method for quantitative determination of BMS-790052 in plasma

d-α-tocopheryl polyethylene glycol 1000 succinate-containing vehicles provide no detectable chemoprotection from oxidative damage

Mouse T cells receive costimulatory signals from LIGHT, a TNF family member

Incisor Degeneration in Rats Induced by Vascular Endothelial Growth Factor/Fibroblast Growth Factor Receptor Tyrosine Kinase Inhibition

Novel Semi-Mechanistic Model Leveraging Preclinical and Clinical Data to Inform the Recommended Phase 2 Dose (RP2D) Selection for Epcoritamab (DuoBody CD3xCD20)

In vivo inhibition of Fas ligand-mediated killing by TR6, a Fas ligand decoy receptor

Duobody-CD3xCD20 Shows Unique and Potent Preclinical Anti-Tumor Activity in Vitro and In Vivo, and Is Being Evaluated Clinically in Patients with B-Cell Malignancies

d-[alpha]-tocopheryl polyethylene glycol 1000 succinate-containing vehicles provide no detectable chemoprotection from oxidative damage

Effect of trifluoromethyl ketone-based elastase inhibitors on neutrophil function in vitro

Modulation of T-cell responses to alloantigens by TR6/DcR3

C-C chemokine receptor 3 antagonism by the beta-chemokine macrophage inflammatory protein 4, a property strongly enhanced by an amino-terminal alanine-methionine swap

BLyS BINDS TO B CELLS WITH HIGH AFFINITY AND INDUCES ACTIVATION OF THE TRANSCRIPTION FACTORS NF-κB AND ELF-1

Orally Active Trifluoromethyl Ketone Inhibitors of Human Leukocyte Elastase

ANALYSIS OF EOSINOPHILS AND MYELOID PROGENITOR RESPONSES TO MODIFIED FORMS OF MPIF-2

Detection of tumor necrosis factor induced nuclear damage with p-phenylenediamine

C-C Chemokine Receptor 3 Antagonism by the {beta}-Chemokine Macrophage Inflammatory Protein 4, a Property Strongly Enhanced by an Amino-Terminal Alanine-Methionine Swap

DuoBody-CD3xCD20 induces potent T-cell-mediated killing of malignant B cells in preclinical models and provides opportunities for subcutaneous dosing

Tumor Rejection and Immune Memory Elicited by Locally Released LEC Chemokine Are Associated with an Impressive Recruitment of APCs, Lymphocytes, and Granulocytes

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