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Germline mutation: de novo mutation in reproductive lineage cells

Genes & Genetic Systems, 2019/02/01, Vol.94(1), pp.3-12

Sakumi, Kunihiko

2019

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Comparative profiling of cortical gene expression in Alzheimer's disease patients and mouse models demonstrates a link between amyloidosis and neuroinflammation

Scientific reports, 2017-12, Vol.7 (1), p.17762-16, Article 17762

2017

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Oxidative damage in nucleic acids and Parkinson's disease

Journal of neuroscience research, 2007-04, Vol.85 (5), p.919-934

2007

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MTH1 and OGG1 maintain a low level of 8-oxoguanine in Alzheimer's brain, and prevent the progression of Alzheimer's pathogenesis

Scientific reports, 2021-03, Vol.11 (1), p.5819-5819, Article 5819

2021

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8-Oxoguanine accumulation in mitochondrial DNA causes mitochondrial dysfunction and impairs neuritogenesis in cultured adult mouse cortical neurons under oxidative conditions

Scientific reports, 2016-02, Vol.6 (1), p.22086-22086, Article 22086

2016

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Human mitochondrial transcriptional factor A breaks the mitochondria-mediated vicious cycle in Alzheimer's disease

Scientific reports, 2016-11, Vol.6 (1), p.37889-37889, Article 37889

2016

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Two distinct pathways of cell death triggered by oxidative damage to nuclear and mitochondrial DNAs

The EMBO journal, 2008-01, Vol.27 (2), p.421-432

2008

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8-Oxoguanine DNA glycosylase (OGG1) deficiency increases susceptibility to obesity and metabolic dysfunction

PloS one, 2012-12, Vol.7 (12), p.e51697

2012

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8-Oxoguanine accumulation in aged female brain impairs neurogenesis in the dentate gyrus and major island of Calleja, causing sexually dimorphic phenotypes

Progress in neurobiology, 2019-09, Vol.180, p.101613-101613, Article 101613

2019

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Inhibitory Effects of Dietary Spirulina platensis on UVB-Induced Skin Inflammatory Responses and Carcinogenesis

Journal of investigative dermatology, 2014-10, Vol.134 (10), p.2610-2619

2014

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Author Correction: Comparative profiling of cortical gene expression in Alzheimer’s disease patients and mouse models demonstrates a link between amyloidosis and neuroinflammation

Scientific reports, 2021-09, Vol.11 (1), p.18377-18377, Article 18377

2021

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Hydrogen in drinking water reduces dopaminergic neuronal loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease

PloS one, 2009-09, Vol.4 (9), p.e7247

2009

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Co-regulation of Cxcl1 and versican in the inflammatory response to UVB induced reactive oxygen species in skin photo-tumorigenesis

Journal of dermatological science, 2017-02, Vol.85 (2), p.140-143

2017

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A high‐fat diet exacerbates the Alzheimer's disease pathology in the hippocampus of the AppNL−F/NL−F knock‐in mouse model

Aging cell, 2021-08, Vol.20 (8), p.e13429-n/a

2021

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Increased Expression of Versican in the Inflammatory Response to UVB- and Reactive Oxygen Species-Induced Skin Tumorigenesis

The American journal of pathology, 2011-12, Vol.179 (6), p.3056-3065

2011

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Deoxyinosine triphosphate induces MLH1/PMS2- and p53-dependent cell growth arrest and DNA instability in mammalian cells

Scientific reports, 2016-09, Vol.6 (1), p.32849-32849, Article 32849

2016

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NUDT16 and ITPA play a dual protective role in maintaining chromosome stability and cell growth by eliminating dIDP/IDP and dITP/ITP from nucleotide pools in mammals

Nucleic acids research, 2010-05, Vol.38 (9), p.2891

2010

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MUTYH-null mice are susceptible to spontaneous and oxidative stress-induced intestinal tumorigenesis

Cancer research (Chicago, Ill.), 2007-07, Vol.67 (14), p.6599-6604

2007

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Narrow-Band UVB Induces More Carcinogenic Skin Tumors than Broad-Band UVB through the Formation of Cyclobutane Pyrimidine Dimer

Journal of investigative dermatology, 2007-12, Vol.127 (12), p.2865-2871

2007

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GDNF promotes neurite outgrowth and upregulates galectin-1 through the RET/PI3K signaling in cultured adult rat dorsal root ganglion neurons

Neurochemistry international, 2013-02, Vol.62 (3), p.330-339

2013

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Fenton reaction‐induced renal carcinogenesis in Mutyh‐deficient mice exhibits less chromosomal aberrations than the rat model

Pathology international, 2017-11, Vol.67 (11), p.564-574

2017

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8-oxoguanine formation induced by chronic UVB exposure makes Ogg1 knockout mice susceptible to skin carcinogenesis

Cancer research (Chicago, Ill.), 2005-07, Vol.65 (14), p.6006-6010

2005

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An Oxidized Purine Nucleoside Triphosphatase, MTH1, Suppresses Cell Death Caused by Oxidative Stress

The Journal of biological chemistry, 2003-09, Vol.278 (39), p.37965-37973

2003

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Germline mutation : de novo mutation in reproductive lineage cells

Genes & Genetic Systems, 2019-02, Vol.94 (1), p.3-12

Kunihiko Sakumi

2019

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Germline mutation: de novo mutation in reproductive lineage cells

Genes & Genetic Systems, 2019, pp.18-00055

Sakumi, Kunihiko

2019

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Germline mutation: de novo mutation in reproductive lineage cells

Comparative profiling of cortical gene expression in Alzheimer's disease patients and mouse models demonstrates a link between amyloidosis and neuroinflammation

Oxidative damage in nucleic acids and Parkinson's disease

MTH1 and OGG1 maintain a low level of 8-oxoguanine in Alzheimer's brain, and prevent the progression of Alzheimer's pathogenesis

8-Oxoguanine accumulation in mitochondrial DNA causes mitochondrial dysfunction and impairs neuritogenesis in cultured adult mouse cortical neurons under oxidative conditions

Human mitochondrial transcriptional factor A breaks the mitochondria-mediated vicious cycle in Alzheimer's disease

Two distinct pathways of cell death triggered by oxidative damage to nuclear and mitochondrial DNAs

8-Oxoguanine DNA glycosylase (OGG1) deficiency increases susceptibility to obesity and metabolic dysfunction

8-Oxoguanine accumulation in aged female brain impairs neurogenesis in the dentate gyrus and major island of Calleja, causing sexually dimorphic phenotypes

Inhibitory Effects of Dietary Spirulina platensis on UVB-Induced Skin Inflammatory Responses and Carcinogenesis

Author Correction: Comparative profiling of cortical gene expression in Alzheimer’s disease patients and mouse models demonstrates a link between amyloidosis and neuroinflammation

Hydrogen in drinking water reduces dopaminergic neuronal loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease

Co-regulation of Cxcl1 and versican in the inflammatory response to UVB induced reactive oxygen species in skin photo-tumorigenesis

A high‐fat diet exacerbates the Alzheimer's disease pathology in the hippocampus of the AppNL−F/NL−F knock‐in mouse model

Increased Expression of Versican in the Inflammatory Response to UVB- and Reactive Oxygen Species-Induced Skin Tumorigenesis

Deoxyinosine triphosphate induces MLH1/PMS2- and p53-dependent cell growth arrest and DNA instability in mammalian cells

NUDT16 and ITPA play a dual protective role in maintaining chromosome stability and cell growth by eliminating dIDP/IDP and dITP/ITP from nucleotide pools in mammals

MUTYH-null mice are susceptible to spontaneous and oxidative stress-induced intestinal tumorigenesis

Narrow-Band UVB Induces More Carcinogenic Skin Tumors than Broad-Band UVB through the Formation of Cyclobutane Pyrimidine Dimer

GDNF promotes neurite outgrowth and upregulates galectin-1 through the RET/PI3K signaling in cultured adult rat dorsal root ganglion neurons

Fenton reaction‐induced renal carcinogenesis in Mutyh‐deficient mice exhibits less chromosomal aberrations than the rat model

8-oxoguanine formation induced by chronic UVB exposure makes Ogg1 knockout mice susceptible to skin carcinogenesis

An Oxidized Purine Nucleoside Triphosphatase, MTH1, Suppresses Cell Death Caused by Oxidative Stress

Germline mutation : de novo mutation in reproductive lineage cells

Germline mutation: de novo mutation in reproductive lineage cells

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