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Does decorin stabilize the extracellular matrix of articular cartilage and slow the progression of osteoarthritis?

Osteoarthritis and cartilage, 2021-08, Vol.29 (8), p.1094-1095

Saklatvala, J.

2021

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The p38 MAP kinase pathway as a therapeutic target in inflammatory disease

Current opinion in pharmacology, 2004-08, Vol.4 (4), p.372-377

Saklatvala, Jeremy

2004

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Transcriptional analysis of micro-dissected articular cartilage in post-traumatic murine osteoarthritis

Osteoarthritis and cartilage, 2015-04, Vol.23 (4), p.616-628

2015

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FGF-2 is bound to perlecan in the pericellular matrix of articular cartilage, where it acts as a chondrocyte mechanotransducer

Osteoarthritis and cartilage, 2007-07, Vol.15 (7), p.752-763

2007

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TRANSCRIPTIONAL AND POST-TRANSCRIPTIONAL CONTROL OF GENE EXPRESSION IN INFLAMMATION

Cytokine, 2002-11, Vol.20 (3), p.91-106

2002

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JNK-dependent modulation of the protease secretome profile of osteoarthritic cartilage

Osteoarthritis and cartilage, 2018-04, Vol.26, p.S108-S109

2018

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Prevalence of radiographic osteoarthritis—it all depends on your point of view

Rheumatology (Oxford, England), 2006-06, Vol.45 (6), p.757-760

2006

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Mitogen-Activated Protein Kinase p38 Controls the Expression and Posttranslational Modification of Tristetraprolin, a Regulator of Tumor Necrosis Factor Alpha mRNA Stability

Molecular and Cellular Biology, 2001-10, Vol.21 (19), p.6461-6469

2001

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Whole blood RNA transcriptional regulation after acute knee injury is associated with clinical outcomes: Early data from the KICK study

Osteoarthritis and cartilage, 2017-04, Vol.25, p.S93-S93

2017

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JNK2 knockout mice are significantly protected from surgically induced osteoarthritis

Osteoarthritis and cartilage, 2015-04, Vol.23, p.A63-A64

2015

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Dexamethasone Destabilizes Cyclooxygenase 2 mRNA by Inhibiting Mitogen-Activated Protein Kinase p38

Molecular and Cellular Biology, 2001-02, Vol.21 (3), p.771-780

2001

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I-26 ACTIVATION OF INFLAMMATORY SIGNALLING IN CARTILAGE BY SOLUBLE AND PHYSICAL STIMULI

Osteoarthritis and cartilage, 2008, Vol.16, p.S8-S8

Saklatvala, J

2008

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Molecular and functional analysis of a conditional knockout of activin A

Osteoarthritis and cartilage, 2014-04, Vol.22, p.S372-S372

2014

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Differential inflammatory gene expression patterns in JNK2 knockout mice in response to IL1, cartilage injury and surgically induced osteoarthritis

Osteoarthritis and cartilage, 2016-04, Vol.24, p.S146-S146

2016

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The 3′ Untranslated Region of Tumor Necrosis Factor Alpha mRNA Is a Target of the mRNA-Stabilizing Factor HuR

Molecular and Cellular Biology, 2001-02, Vol.21 (3), p.721-730

2001

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Interleukin 1 induces aggrecan degradation by human articular chondrocytes through a TAK1/MKK4/JNK2 pathway without involvement of NFKB

Osteoarthritis and cartilage, 2013-04, Vol.21, p.S127-S127

2013

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A significant role for the JNK pathway in regulating interleukin 1 induced-aggrecan degradation in human articular chondrocytes

Osteoarthritis and cartilage, 2015-04, Vol.23, p.A152-A152

2015

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Molecular changes in synovial fluid following human knee injury are associated with early clinical outcomes

Osteoarthritis and cartilage, 2016-04, Vol.24, p.S22-S22

2016

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TNFAIP6 and SAA1 mRNA levels are elevated in peripheral blood cells following destabilising knee injuries

Osteoarthritis and cartilage, 2016-04, Vol.24, p.S82-S83

2016

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Development of a novel 2D proteomics approach for the identification of proteins secreted by primary chondrocytes after stimulation by IL-1 and oncostatin M

Rheumatology (Oxford, England), 2006-09, Vol.45 (9), p.1101-1109

2006

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Activin bA determines osteophyte size in female mice after surgical joint destabilization

Osteoarthritis and cartilage, 2015-04, Vol.23, p.A296-A297

2015

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Acute and sustained molecular changes in synovial fluid following acute knee injury mirror the murine joint injury response

Osteoarthritis and cartilage, 2014-04, Vol.22, p.S7-S8

2014

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A p38 MAP kinase inhibitor regulates stability of interleukin-1-induced cyclooxygenase-2 mRNA

FEBS letters, 1998-11, Vol.439 (1), p.75-80

1998

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IL18 is secreted upon joint injury and is a key pathogenic cytokine in murine osteoarthritis

Osteoarthritis and cartilage, 2014-04, Vol.22, p.S131-S132

2014

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The molecular response to acute joint destabilisation is altered in female compared to male mice

Osteoarthritis and cartilage, 2012-04, Vol.20, p.S120-S121

2012

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Does decorin stabilize the extracellular matrix of articular cartilage and slow the progression of osteoarthritis?

The p38 MAP kinase pathway as a therapeutic target in inflammatory disease

Transcriptional analysis of micro-dissected articular cartilage in post-traumatic murine osteoarthritis

FGF-2 is bound to perlecan in the pericellular matrix of articular cartilage, where it acts as a chondrocyte mechanotransducer

TRANSCRIPTIONAL AND POST-TRANSCRIPTIONAL CONTROL OF GENE EXPRESSION IN INFLAMMATION

JNK-dependent modulation of the protease secretome profile of osteoarthritic cartilage

Prevalence of radiographic osteoarthritis—it all depends on your point of view

Mitogen-Activated Protein Kinase p38 Controls the Expression and Posttranslational Modification of Tristetraprolin, a Regulator of Tumor Necrosis Factor Alpha mRNA Stability

Whole blood RNA transcriptional regulation after acute knee injury is associated with clinical outcomes: Early data from the KICK study

JNK2 knockout mice are significantly protected from surgically induced osteoarthritis

Dexamethasone Destabilizes Cyclooxygenase 2 mRNA by Inhibiting Mitogen-Activated Protein Kinase p38

I-26 ACTIVATION OF INFLAMMATORY SIGNALLING IN CARTILAGE BY SOLUBLE AND PHYSICAL STIMULI

Molecular and functional analysis of a conditional knockout of activin A

Differential inflammatory gene expression patterns in JNK2 knockout mice in response to IL1, cartilage injury and surgically induced osteoarthritis

The 3′ Untranslated Region of Tumor Necrosis Factor Alpha mRNA Is a Target of the mRNA-Stabilizing Factor HuR

Interleukin 1 induces aggrecan degradation by human articular chondrocytes through a TAK1/MKK4/JNK2 pathway without involvement of NFKB

A significant role for the JNK pathway in regulating interleukin 1 induced-aggrecan degradation in human articular chondrocytes

Molecular changes in synovial fluid following human knee injury are associated with early clinical outcomes

TNFAIP6 and SAA1 mRNA levels are elevated in peripheral blood cells following destabilising knee injuries

Development of a novel 2D proteomics approach for the identification of proteins secreted by primary chondrocytes after stimulation by IL-1 and oncostatin M

Activin bA determines osteophyte size in female mice after surgical joint destabilization

Acute and sustained molecular changes in synovial fluid following acute knee injury mirror the murine joint injury response

A p38 MAP kinase inhibitor regulates stability of interleukin-1-induced cyclooxygenase-2 mRNA

IL18 is secreted upon joint injury and is a key pathogenic cytokine in murine osteoarthritis

The molecular response to acute joint destabilisation is altered in female compared to male mice

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