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Overview of Potential Clinical Applications of Hemoglobin Vesicles (HbV) as Artificial Red Cells, Evidenced by Preclinical Studies of the Academic Research Consortium

Journal of functional biomaterials, 2017-03, Vol.8 (1), p.10

Sakai, Hiromi

2017

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Preparation of Artificial Red Blood Cells (Hemoglobin Vesicles) Using the Rotation–Revolution Mixer for High Encapsulation Efficiency

ACS biomaterials science & engineering, 2021-06, Vol.7 (6), p.2835-2844

2021

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Artificial oxygen carriers, from nanometer- to micrometer-sized particles, made of hemoglobin composites substituting for red blood cells

Particuology, 2022-05, Vol.64, p.43-55

2022

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Translational Research of Hemoglobin Vesicles as a Transfusion Alternative

Current medicinal chemistry, 2022-01, Vol.29 (3), p.591-606

2022

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Transmembrane Difference in Colloid Osmotic Pressure Affects the Lipid Membrane Fluidity of Liposomes Encapsulating a Concentrated Protein Solution

Langmuir, 2017-02, Vol.33 (6), p.1533-1540

2017

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Effect of carbon monoxide administration using haemoglobin-vesicles on the hippocampal tissue

Artificial cells, nanomedicine, and biotechnology, 2022-12, Vol.50 (1), p.1-9

2022

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Liposome-encapsulated methemoglobin as an antidote against cyanide poisoning

Journal of controlled release, 2021-09, Vol.337, p.59-70

2021

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Long-term pharmaceutical stability of liposome-encapsulated methemoglobin as an antidote for cyanide poisoning

International journal of pharmaceutics, 2021-12, Vol.610, p.121260, Article 121260

2021

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Liposomal methemoglobin as a potent antidote for hydrogen sulfide poisoning

Toxicology and applied pharmacology, 2022-09, Vol.450, p.116159-116159, Article 116159

2022

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Structural insights into the substrate specificity of IMP-6 and IMP-1 metallo-β-lactamases

Journal of biochemistry (Tokyo), 2023-01, Vol.173 (1), p.21-30

2023

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Long-Term Stored Hemoglobin-Vesicles, a Cellular Type of Hemoglobin-Based Oxygen Carrier, Has Resuscitative Effects Comparable to That for Fresh Red Blood Cells in a Rat Model with Massive Hemorrhage without Post-Transfusion Lung Injury

PloS one, 2016-10, Vol.11 (10), p.e0165557-e0165557

2016

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Resuscitative efficacy of hemoglobin vesicles for severe postpartum hemorrhage in pregnant rabbits

Scientific reports, 2021-11, Vol.11 (1), p.22367-22367, Article 22367

2021

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Liposome‐encapsulated hemoglobin (HbV) transfusion rescues rats undergoing progressive lethal 85% hemorrhage as a result of an anti‐arrhythmogenic effect on the myocardium

Artificial organs, 2021-11, Vol.45 (11), p.1391-1404

2021

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Prolonged functional life span of artificial red cells in blood circulation by repeated methylene blue injections

Artificial cells, nanomedicine, and biotechnology, 2019-12, Vol.47 (1), p.3123-3128

2019

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Present situation of the development of cellular-type hemoglobin-based oxygen carrier (hemoglobin-vesicles)

Current drug discovery technologies, 2012-09, Vol.9 (3), p.188-193

Sakai, Hiromi

2012

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Exploring how plasma- and muscle-related parameters affect trout hemolysis as a route to prevent hemoglobin-mediated lipid oxidation of fish muscle

Scientific reports, 2022-08, Vol.12 (1), p.13446-13446, Article 13446

2022

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Photosensitizer Effects of Artificial Red Cells on Dye Laser Irradiation in an Animal Model Assuming Port-Wine Stain Treatment

Plastic and reconstructive surgery (1963), 2017-03, Vol.139 (3), p.707e-716e

2017

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Research of storable and ready-to-use artificial red blood cells (hemoglobin vesicles) for emergency medicine and other clinical applications

Frontiers in medical technology, 2022-12, Vol.4, p.1048951

2022

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Myocardial Electrical Remodeling and the Arrhythmogenic Substrate in Hemorrhagic Shock-Induced Heart: Anti-Arrhythmogenic Effect of Liposome-Encapsulated Hemoglobin (HbV) on the Myocardium

Shock (Augusta, Ga.), 2019-09, Vol.52 (3), p.378-386

2019

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Potential Electron Mediators to Extract Electron Energies of RBC Glycolysis for Prolonged in Vivo Functional Lifetime of Hemoglobin Vesicles

Bioconjugate chemistry, 2015-04, Vol.26 (4), p.746-754

2015

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Selecting Pedal Load for Lower-Limb Rehabilitation Based on the Combination of Muscle Synergy and Fourier Series

Journal of advanced computational intelligence and intelligent informatics, 2024-05, Vol.28 (3), p.595-605

2024

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Artificial red blood cells increase large vessel wall damage and decrease surrounding dermal tissue damage in a rabbit auricle model after subsequent flashlamp‐pumped pulsed‐dye laser treatment

Journal of dermatology, 2021-05, Vol.48 (5), p.600-612

2021

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Impact of human-derived hemoglobin based oxygen vesicles as a machine perfusion solution for liver donation after cardiac death in a pig model

PloS one, 2019-12, Vol.14 (12), p.e0226183

2019

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Assessing cytochrome P450-based drug-drug interactions with hemoglobin-vesicles, an artificial red blood cell preparation, in healthy rats

Drug metabolism and pharmacokinetics, 2020-10, Vol.35 (5), p.425-431

2020

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A novel serum-free monolayer culture for orderly hematopoietic differentiation of human pluripotent cells via mesodermal progenitors

PloS one, 2011-07, Vol.6 (7), p.e22261

2011

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Overview of Potential Clinical Applications of Hemoglobin Vesicles (HbV) as Artificial Red Cells, Evidenced by Preclinical Studies of the Academic Research Consortium

Preparation of Artificial Red Blood Cells (Hemoglobin Vesicles) Using the Rotation–Revolution Mixer for High Encapsulation Efficiency

Artificial oxygen carriers, from nanometer- to micrometer-sized particles, made of hemoglobin composites substituting for red blood cells

Translational Research of Hemoglobin Vesicles as a Transfusion Alternative

Transmembrane Difference in Colloid Osmotic Pressure Affects the Lipid Membrane Fluidity of Liposomes Encapsulating a Concentrated Protein Solution

Effect of carbon monoxide administration using haemoglobin-vesicles on the hippocampal tissue

Liposome-encapsulated methemoglobin as an antidote against cyanide poisoning

Long-term pharmaceutical stability of liposome-encapsulated methemoglobin as an antidote for cyanide poisoning

Liposomal methemoglobin as a potent antidote for hydrogen sulfide poisoning

Structural insights into the substrate specificity of IMP-6 and IMP-1 metallo-β-lactamases

Long-Term Stored Hemoglobin-Vesicles, a Cellular Type of Hemoglobin-Based Oxygen Carrier, Has Resuscitative Effects Comparable to That for Fresh Red Blood Cells in a Rat Model with Massive Hemorrhage without Post-Transfusion Lung Injury

Resuscitative efficacy of hemoglobin vesicles for severe postpartum hemorrhage in pregnant rabbits

Liposome‐encapsulated hemoglobin (HbV) transfusion rescues rats undergoing progressive lethal 85% hemorrhage as a result of an anti‐arrhythmogenic effect on the myocardium

Prolonged functional life span of artificial red cells in blood circulation by repeated methylene blue injections

Present situation of the development of cellular-type hemoglobin-based oxygen carrier (hemoglobin-vesicles)

Exploring how plasma- and muscle-related parameters affect trout hemolysis as a route to prevent hemoglobin-mediated lipid oxidation of fish muscle

Photosensitizer Effects of Artificial Red Cells on Dye Laser Irradiation in an Animal Model Assuming Port-Wine Stain Treatment

Research of storable and ready-to-use artificial red blood cells (hemoglobin vesicles) for emergency medicine and other clinical applications

Myocardial Electrical Remodeling and the Arrhythmogenic Substrate in Hemorrhagic Shock-Induced Heart: Anti-Arrhythmogenic Effect of Liposome-Encapsulated Hemoglobin (HbV) on the Myocardium

Potential Electron Mediators to Extract Electron Energies of RBC Glycolysis for Prolonged in Vivo Functional Lifetime of Hemoglobin Vesicles

Selecting Pedal Load for Lower-Limb Rehabilitation Based on the Combination of Muscle Synergy and Fourier Series

Artificial red blood cells increase large vessel wall damage and decrease surrounding dermal tissue damage in a rabbit auricle model after subsequent flashlamp‐pumped pulsed‐dye laser treatment

Impact of human-derived hemoglobin based oxygen vesicles as a machine perfusion solution for liver donation after cardiac death in a pig model

Assessing cytochrome P450-based drug-drug interactions with hemoglobin-vesicles, an artificial red blood cell preparation, in healthy rats

A novel serum-free monolayer culture for orderly hematopoietic differentiation of human pluripotent cells via mesodermal progenitors

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