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Aldehyde-induced DNA-protein crosslinks- DNA damage, repair and mutagenesis

Frontiers in oncology, 2024-09, Vol.14, p.1478373

2024

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An APOBEC3A hypermutation signature is distinguishable from the signature of background mutagenesis by APOBEC3B in human cancers

Nature genetics, 2015-09, Vol.47 (9), p.1067-1072

2015

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Similarity between mutation spectra in hypermutated genomes of rubella virus and in SARS-CoV-2 genomes accumulated during the COVID-19 pandemic

PloS one, 2020-10, Vol.15 (10), p.e0237689

2020

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Infectious vaccine-derived rubella viruses emerge, persist, and evolve in cutaneous granulomas of children with primary immunodeficiencies

PLoS pathogens, 2019-10, Vol.15 (10), p.e1008080

2019

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Repair of multiple simultaneous double-strand breaks causes bursts of genome-wide clustered hypermutation

PLoS biology, 2019-09, Vol.17 (9), p.e3000464

2019

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UV-exposure, endogenous DNA damage, and DNA replication errors shape the spectra of genome changes in human skin

PLoS genetics, 2021-01, Vol.17 (1), p.e1009302

2021

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The Impact of Environmental and Endogenous Damage on Somatic Mutation Load in Human Skin Fibroblasts

PLoS genetics, 2016-10, Vol.12 (10), p.e1006385

2016

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When secondary comes first – The importance of non-canonical DNA structures

Biochimie, 2013-02, Vol.95 (2), p.117-123

2013

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Mutational signatures of redox stress in yeast single-strand DNA and of aging in human mitochondrial DNA share a common feature

PLoS biology, 2019-05, Vol.17 (5), p.e3000263

2019

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Aldehyde-Associated MutagenesisCurrent State of Knowledge

Chemical research in toxicology, 2023-07, Vol.36 (7), p.983-1001

2023

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Genome-wide screen reveals replication pathway for quasi-palindrome fragility dependent on homologous recombination

PLoS genetics, 2013-12, Vol.9 (12), p.e1003979-e1003979

2013

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Correction: Repair of multiple simultaneous double-strand breaks causes bursts of genome-wide clustered hypermutation

PLoS biology, 2020-03, Vol.18 (3), p.e3000695-e3000695

2020

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Fragile DNA motifs trigger mutagenesis at distant chromosomal loci in saccharomyces cerevisiae

PLoS genetics, 2013-06, Vol.9 (6), p.e1003551

2013

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Hypermutation in single-stranded DNA

DNA repair, 2020-07, Vol.91-92, p.102868-102868, Article 102868

2020

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Acetaldehyde makes a distinct mutation signature in single-stranded DNA

Nucleic acids research, 2022-07, Vol.50 (13), p.7451-7464

2022

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Migrating bubble during break-induced replication drives conservative DNA synthesis

Nature (London), 2013-10, Vol.502 (7471), p.389-392

2013

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The Journey of DNA Repair

Trends in Cancer, 2015-12, Vol.1 (4), p.215-216

Saini, Natalie

2015

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Somatic mutation load and spectra: A record of DNA damage and repair in healthy human cells

Environmental and molecular mutagenesis, 2018-10, Vol.59 (8), p.672-686

2018

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Analysis of APOBEC-induced mutations in yeast strains with low levels of replicative DNA polymerases

Proceedings of the National Academy of Sciences - PNAS, 2020-04, Vol.117 (17), p.9440-9450

2020

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Mutation signatures specific to DNA alkylating agents in yeast and cancers

Nucleic acids research, 2020-04, Vol.48 (7), p.3692-3707

2020

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Glycidamide-induced hypermutation in yeast single-stranded DNA reveals a ubiquitous clock-like mutational motif in humans

Nucleic acids research, 2023-09, Vol.51 (17), p.9075-9100

2023

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APOBEC3B cytidine deaminase targets the non-transcribed strand of tRNA genes in yeast

DNA repair, 2017-05, Vol.53, p.4-14

2017

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Three distinct pathways for double‐strand break formation at palindromic repeats in yeast (735.10)

The FASEB journal, 2014-04, Vol.28 (S1), p.n/a

2014

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Genome-Wide Screen Reveals Replication Pathway for Quasi-Palindrome Fragility Dependent on Homologous Recombination: e1003979

PLoS genetics, 2013-12, Vol.9 (12)

2013

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Genome-wide Screen Identifies Pathways that Govern GAA/TTC Repeat Fragility and Expansions in Dividing and Nondividing Yeast Cells

Molecular cell, 2012-10, Vol.48 (2), p.254-265

2012

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Aldehyde-induced DNA-protein crosslinks- DNA damage, repair and mutagenesis

An APOBEC3A hypermutation signature is distinguishable from the signature of background mutagenesis by APOBEC3B in human cancers

Similarity between mutation spectra in hypermutated genomes of rubella virus and in SARS-CoV-2 genomes accumulated during the COVID-19 pandemic

Infectious vaccine-derived rubella viruses emerge, persist, and evolve in cutaneous granulomas of children with primary immunodeficiencies

Repair of multiple simultaneous double-strand breaks causes bursts of genome-wide clustered hypermutation

UV-exposure, endogenous DNA damage, and DNA replication errors shape the spectra of genome changes in human skin

The Impact of Environmental and Endogenous Damage on Somatic Mutation Load in Human Skin Fibroblasts

When secondary comes first – The importance of non-canonical DNA structures

Mutational signatures of redox stress in yeast single-strand DNA and of aging in human mitochondrial DNA share a common feature

Aldehyde-Associated MutagenesisCurrent State of Knowledge

Genome-wide screen reveals replication pathway for quasi-palindrome fragility dependent on homologous recombination

Correction: Repair of multiple simultaneous double-strand breaks causes bursts of genome-wide clustered hypermutation

Fragile DNA motifs trigger mutagenesis at distant chromosomal loci in saccharomyces cerevisiae

Hypermutation in single-stranded DNA

Acetaldehyde makes a distinct mutation signature in single-stranded DNA

Migrating bubble during break-induced replication drives conservative DNA synthesis

The Journey of DNA Repair

Somatic mutation load and spectra: A record of DNA damage and repair in healthy human cells

Analysis of APOBEC-induced mutations in yeast strains with low levels of replicative DNA polymerases

Mutation signatures specific to DNA alkylating agents in yeast and cancers

Glycidamide-induced hypermutation in yeast single-stranded DNA reveals a ubiquitous clock-like mutational motif in humans

APOBEC3B cytidine deaminase targets the non-transcribed strand of tRNA genes in yeast

Three distinct pathways for double‐strand break formation at palindromic repeats in yeast (735.10)

Genome-Wide Screen Reveals Replication Pathway for Quasi-Palindrome Fragility Dependent on Homologous Recombination: e1003979

Genome-wide Screen Identifies Pathways that Govern GAA/TTC Repeat Fragility and Expansions in Dividing and Nondividing Yeast Cells

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