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Mechanistic approach of the inhibitory effect of chrysin on inflammatory and apoptotic events implicated in radiation-induced premature ovarian failure: Emphasis on TGF-β/MAPKs signaling pathway

Biomedicine & pharmacotherapy, 2019-01, Vol.109, p.293-303

2019

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Coenzyme Q10 mitigates ionizing radiation-induced testicular damage in rats through inhibition of oxidative stress and mitochondria-mediated apoptotic cell death

Toxicology and applied pharmacology, 2019-11, Vol.383, p.114780, Article 114780

2019

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Mechanistic perspective of protective effects of resveratrol against cisplatin-induced ovarian injury in rats: emphasis on anti-inflammatory and anti-apoptotic effects

Naunyn-Schmiedeberg's archives of pharmacology, 2019-10, Vol.392 (10), p.1225-1238

2019

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Bone Marrow-Derived Mesenchymal Stem Cells Reverse Radiotherapy-Induced Premature Ovarian Failure: Emphasis on Signal Integration of TGF-β, Wnt/β-Catenin and Hippo Pathways

Stem cell reviews and reports, 2021-08, Vol.17 (4), p.1429-1445

2021

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Sodium selenite improves folliculogenesis in radiation-induced ovarian failure: a mechanistic approach

PloS one, 2012-12, Vol.7 (12), p.e50928-e50928

2012

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Protective effects of Brownea grandiceps (Jacq.) against ϒ-radiation-induced enteritis in rats in relation to its secondary metabolome fingerprint

Biomedicine & pharmacotherapy, 2022-02, Vol.146, p.112603-112603, Article 112603

2022

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Coenzyme Q10 attenuates inflammation and fibrosis implicated in radiation enteropathy through suppression of NF-kB/TGF-β/MMP-9 pathways

International immunopharmacology, 2021-03, Vol.92, p.107347-107347, Article 107347

2021

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Neuroprotective effects of saxagliptin against radiation-induced cognitive impairment: Insights on Akt/CREB/SIRT1/BDNF signaling pathway

Toxicology and applied pharmacology, 2024-08, Vol.489, p.116994, Article 116994

2024

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Hesperidin attenuates radiation-induced ovarian failure in rats: Emphasis on TLR-4/NF-ĸB signaling pathway

Toxicology and applied pharmacology, 2024-11, Vol.492, p.117111, Article 117111

2024

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Phytoestrogen genistein hinders ovarian oxidative damage and apoptotic cell death-induced by ionizing radiation: co-operative role of ER-β, TGF-β, and FOXL-2

Scientific reports, 2020-08, Vol.10 (1), p.13551, Article 13551

2020

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Novel molecular mechanisms underlying the ameliorative effect of N-acetyl-L-cysteine against ϒ-radiation-induced premature ovarian failure in rats

Ecotoxicology and environmental safety, 2020-12, Vol.206, p.111190-111190, Article 111190

2020

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Promising drug repurposing approach targeted for cytokine storm implicated in SARS-CoV-2 complications

Immunopharmacology and immunotoxicology, 2021-07, Vol.43 (4), p.395-409

2021

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Hibiscus schizopetalus boosts wound healing via restoring redox balance and hindering inflammatory responses in rats: Insights on metabolome profiling and molecular docking

Archiv der Pharmazie (Weinheim), 2024-11, Vol.357 (11), p.e2400392-n/a

2024

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Chemical constituents and gastro-protective potential of Pachira glabra leaves against ethanol-induced gastric ulcer in experimental rat model

Inflammopharmacology, 2021-02, Vol.29 (1), p.317-332

2021

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Resveratrol inhibits inflammatory signaling implicated in ionizing radiation-induced premature ovarian failure through antagonistic crosstalk between silencing information regulator 1 (SIRT1) and poly(ADP-ribose) polymerase 1 (PARP-1)

Biochemical pharmacology, 2016-03, Vol.103, p.140-150

2016

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Synthesis, molecular modelling and QSAR study of new N-phenylacetamide-2-oxoindole benzensulfonamide conjugates as carbonic anhydrase inhibitors with antiproliferative activity

Journal of enzyme inhibition and medicinal chemistry, 2022-12, Vol.37 (1), p.701-717

2022

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New NSAID Conjugates as Potent and Selective COX-2 Inhibitors: Synthesis, Molecular Modeling and Biological Investigation

Molecules (Basel, Switzerland), 2023-02, Vol.28 (4), p.1945

2023

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Insight on development of oxazole and imidazole derivatives as COX inhibitors with anti-inflammatory effects

Journal of molecular structure, 2025-02, Vol.1321, p.140148, Article 140148

2025

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Assessment of heavy metals contamination of sediments and surface waters of Bitter lake, Suez Canal, Egypt: Ecological risks and human health

Marine pollution bulletin, 2023-07, Vol.192, p.115096-115096, Article 115096

2023

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Synthesis and selective inhibitory effects of some 2-oxindole benzenesulfonamide conjugates on human carbonic anhydrase isoforms CA I, CA II, CA IX and CAXII

Bioorganic chemistry, 2020-01, Vol.95, p.103514, Article 103514

2020

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Investigations of new N1-substituted pyrazoles as anti-inflammatory and analgesic agents having COX inhibitory activity

Future medicinal chemistry, 2024-02, Vol.16 (4), p.349-368

2024

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Exploring of novel oxazolones and imidazolones as anti-inflammatory and analgesic candidates with cyclooxygenase inhibitory action

Future medicinal chemistry, 2024, Vol.16 (10), p.963-981

2024

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The tyrosine kinase inhibitor, sunitinib malate, induces cognitive impairment in vivo via dysregulating VEGFR signaling, apoptotic and autophagic machineries

Experimental neurology, 2016-09, Vol.283 (Pt A), p.129-141

2016

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Validation of FIB-6 score in assessment of liver fibrosis in chronic hepatitis B

Saudi journal of gastroenterology, 2024-05, Vol.30 (3), p.138-144

2024

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Simulating spatial–temporal urban growth of a Moroccan metropolitan using CA–Markov model

Spatial Information Research, 2020, 28(5), 116, pp.609-621

2020

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Mechanistic approach of the inhibitory effect of chrysin on inflammatory and apoptotic events implicated in radiation-induced premature ovarian failure: Emphasis on TGF-β/MAPKs signaling pathway

Coenzyme Q10 mitigates ionizing radiation-induced testicular damage in rats through inhibition of oxidative stress and mitochondria-mediated apoptotic cell death

Mechanistic perspective of protective effects of resveratrol against cisplatin-induced ovarian injury in rats: emphasis on anti-inflammatory and anti-apoptotic effects

Bone Marrow-Derived Mesenchymal Stem Cells Reverse Radiotherapy-Induced Premature Ovarian Failure: Emphasis on Signal Integration of TGF-β, Wnt/β-Catenin and Hippo Pathways

Sodium selenite improves folliculogenesis in radiation-induced ovarian failure: a mechanistic approach

Protective effects of Brownea grandiceps (Jacq.) against ϒ-radiation-induced enteritis in rats in relation to its secondary metabolome fingerprint

Coenzyme Q10 attenuates inflammation and fibrosis implicated in radiation enteropathy through suppression of NF-kB/TGF-β/MMP-9 pathways

Neuroprotective effects of saxagliptin against radiation-induced cognitive impairment: Insights on Akt/CREB/SIRT1/BDNF signaling pathway

Hesperidin attenuates radiation-induced ovarian failure in rats: Emphasis on TLR-4/NF-ĸB signaling pathway

Phytoestrogen genistein hinders ovarian oxidative damage and apoptotic cell death-induced by ionizing radiation: co-operative role of ER-β, TGF-β, and FOXL-2

Novel molecular mechanisms underlying the ameliorative effect of N-acetyl-L-cysteine against ϒ-radiation-induced premature ovarian failure in rats

Promising drug repurposing approach targeted for cytokine storm implicated in SARS-CoV-2 complications

Hibiscus schizopetalus boosts wound healing via restoring redox balance and hindering inflammatory responses in rats: Insights on metabolome profiling and molecular docking

Chemical constituents and gastro-protective potential of Pachira glabra leaves against ethanol-induced gastric ulcer in experimental rat model

Resveratrol inhibits inflammatory signaling implicated in ionizing radiation-induced premature ovarian failure through antagonistic crosstalk between silencing information regulator 1 (SIRT1) and poly(ADP-ribose) polymerase 1 (PARP-1)

Synthesis, molecular modelling and QSAR study of new N-phenylacetamide-2-oxoindole benzensulfonamide conjugates as carbonic anhydrase inhibitors with antiproliferative activity

New NSAID Conjugates as Potent and Selective COX-2 Inhibitors: Synthesis, Molecular Modeling and Biological Investigation

Insight on development of oxazole and imidazole derivatives as COX inhibitors with anti-inflammatory effects

Assessment of heavy metals contamination of sediments and surface waters of Bitter lake, Suez Canal, Egypt: Ecological risks and human health

Synthesis and selective inhibitory effects of some 2-oxindole benzenesulfonamide conjugates on human carbonic anhydrase isoforms CA I, CA II, CA IX and CAXII

Investigations of new N1-substituted pyrazoles as anti-inflammatory and analgesic agents having COX inhibitory activity

Exploring of novel oxazolones and imidazolones as anti-inflammatory and analgesic candidates with cyclooxygenase inhibitory action

The tyrosine kinase inhibitor, sunitinib malate, induces cognitive impairment in vivo via dysregulating VEGFR signaling, apoptotic and autophagic machineries

Validation of FIB-6 score in assessment of liver fibrosis in chronic hepatitis B

Simulating spatial–temporal urban growth of a Moroccan metropolitan using CA–Markov model

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