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Lantibiotics: mode of action, biosynthesis and bioengineering

Current pharmaceutical biotechnology, 2009-01, Vol.10 (1), p.2-18

2009

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Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry for Fast and Reliable Identification of Clinical Yeast Isolates

Journal of Clinical Microbiology, 2009-09, Vol.47 (9), p.2912-2917

2009

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The Lipopeptide Antibiotic Friulimicin B Inhibits Cell Wall Biosynthesis through Complex Formation with Bactoprenol Phosphate

Antimicrobial Agents and Chemotherapy, 2009-04, Vol.53 (4), p.1610-1618

2009

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Use of the Cell Wall Precursor Lipid II by a Pore-Forming Peptide Antibiotic

Science (American Association for the Advancement of Science), 1999-12, Vol.286 (5448), p.2361-2364

1999

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Naturally Processed Dermcidin-Derived Peptides Do Not Permeabilize Bacterial Membranes and Kill Microorganisms Irrespective of Their Charge

Antimicrobial Agents and Chemotherapy, 2006-08, Vol.50 (8), p.2608-2620

2006

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Analysis of in vitro activities and modes of action of synthetic antimicrobial peptides derived from an α-helical ‘sequence template’

Journal of antimicrobial chemotherapy, 2008-02, Vol.61 (2), p.341-352

2008

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LANTIBIOTICS: Biosynthesis and Biological Activities of Uniquely Modified Peptides from Gram-Positive Bacteria

Annual review of microbiology, 1998-01, Vol.52 (1), p.41-79

1998

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Mechanism of Action and Limited Cross-Resistance of New Lipopeptide MX-2401

Antimicrobial Agents and Chemotherapy, 2011-06, Vol.55 (6), p.2743-2754

2011

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In vitro activity and mode of action of diastereomeric antimicrobial peptides against bacterial clinical isolates

Journal of antimicrobial chemotherapy, 2004-02, Vol.53 (2), p.230-239

2004

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Influence of Ca²⁺ Ions on the Activity of Lantibiotics Containing a Mersacidin-Like Lipid II Binding Motif

Applied and Environmental Microbiology, 2009-07, Vol.75 (13), p.4427-4434

2009

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Multiple activities in lantibiotics--models for the design of novel antibiotics?

Current pharmaceutical design, 2002-01, Vol.8 (9), p.815-833

2002

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The Lantibiotic Mersacidin Inhibits Peptidoglycan Synthesis by Targeting Lipid II

Antimicrobial Agents and Chemotherapy, 1998-01, Vol.42 (1), p.154-160

1998

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Role of lipid‐bound peptidoglycan precursors in the formation of pores by nisin, epidermin and other lantibiotics

Molecular microbiology, 1998-10, Vol.30 (2), p.317-327

1998

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Presence of Staphylococcus aureus with reduced susceptibility to vancomycin in Germany

European journal of clinical microbiology & infectious diseases, 1999-10, Vol.18 (10), p.691-696

1999

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Differential expression of α- and β-defensins in human peripheral blood

European journal of clinical investigation, 2003-01, Vol.33 (1), p.82-87

2003

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Purification and Partial Characterization of a Murein Hydrolase, Millericin B, Produced by Streptococcus milleri NMSCC 061

Applied and Environmental Microbiology, 2000-01, Vol.66 (1), p.23-28

2000

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Two-component anti-Staphylococcus aureus lantibiotic activity produced by Staphylococcus aureus C55

Applied and environmental microbiology, 1998-12, Vol.64 (12), p.4803-4808

1998

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Isolation, Characterization, and Heterologous Expression of the Novel Lantibiotic Epicidin 280 and Analysis of Its Biosynthetic Gene Cluster

Applied and Environmental Microbiology, 1998-09, Vol.64 (9), p.3140-3146

1998

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Identification of antibacterial peptides from endophytic microbiome

Applied microbiology and biotechnology, 2016-11, Vol.100 (21), p.9283-9293

2016

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Mode of action of the lantibiotic mersacidin: inhibition of peptidoglycan biosynthesis via a novel mechanism?

Antimicrobial Agents and Chemotherapy, 1995-03, Vol.39 (3), p.714-719

1995

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New insights into the mechanism of action of lantibiotics—diverse biological effects by binding to the same molecular target

Journal of antimicrobial chemotherapy, 2000-07, Vol.46 (1), p.1-6

2000

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Mammalian defensins: structures and mechanism of antibiotic activity

Journal of leukocyte biology, 2005-04, Vol.77 (4), p.466-475

2005

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Specific Binding of Nisin to the Peptidoglycan Precursor Lipid II Combines Pore Formation and Inhibition of Cell Wall Biosynthesis for Potent Antibiotic Activity

The Journal of biological chemistry, 2001-01, Vol.276 (3), p.1772-1779

2001

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Engineering of a novel thioether bridge and role of modified residues in the lantibiotic Pep5

Applied and Environmental Microbiology, 1996-02, Vol.62 (2), p.385-392

1996

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Lipid II-Mediated Pore Formation by the Peptide Antibiotic Nisin: a Black Lipid Membrane Study

Journal of Bacteriology, 2004-05, Vol.186 (10), p.3259-3261

2004

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Lantibiotics: mode of action, biosynthesis and bioengineering

Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry for Fast and Reliable Identification of Clinical Yeast Isolates

The Lipopeptide Antibiotic Friulimicin B Inhibits Cell Wall Biosynthesis through Complex Formation with Bactoprenol Phosphate

Use of the Cell Wall Precursor Lipid II by a Pore-Forming Peptide Antibiotic

Naturally Processed Dermcidin-Derived Peptides Do Not Permeabilize Bacterial Membranes and Kill Microorganisms Irrespective of Their Charge

Analysis of in vitro activities and modes of action of synthetic antimicrobial peptides derived from an α-helical ‘sequence template’

LANTIBIOTICS: Biosynthesis and Biological Activities of Uniquely Modified Peptides from Gram-Positive Bacteria

Mechanism of Action and Limited Cross-Resistance of New Lipopeptide MX-2401

In vitro activity and mode of action of diastereomeric antimicrobial peptides against bacterial clinical isolates

Influence of Ca²⁺ Ions on the Activity of Lantibiotics Containing a Mersacidin-Like Lipid II Binding Motif

Multiple activities in lantibiotics--models for the design of novel antibiotics?

The Lantibiotic Mersacidin Inhibits Peptidoglycan Synthesis by Targeting Lipid II

Role of lipid‐bound peptidoglycan precursors in the formation of pores by nisin, epidermin and other lantibiotics

Presence of Staphylococcus aureus with reduced susceptibility to vancomycin in Germany

Differential expression of α- and β-defensins in human peripheral blood

Purification and Partial Characterization of a Murein Hydrolase, Millericin B, Produced by Streptococcus milleri NMSCC 061

Two-component anti-Staphylococcus aureus lantibiotic activity produced by Staphylococcus aureus C55

Isolation, Characterization, and Heterologous Expression of the Novel Lantibiotic Epicidin 280 and Analysis of Its Biosynthetic Gene Cluster

Identification of antibacterial peptides from endophytic microbiome

Mode of action of the lantibiotic mersacidin: inhibition of peptidoglycan biosynthesis via a novel mechanism?

New insights into the mechanism of action of lantibiotics—diverse biological effects by binding to the same molecular target

Mammalian defensins: structures and mechanism of antibiotic activity

Specific Binding of Nisin to the Peptidoglycan Precursor Lipid II Combines Pore Formation and Inhibition of Cell Wall Biosynthesis for Potent Antibiotic Activity

Engineering of a novel thioether bridge and role of modified residues in the lantibiotic Pep5

Lipid II-Mediated Pore Formation by the Peptide Antibiotic Nisin: a Black Lipid Membrane Study

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