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Intravital imaging of SRF and Notch signalling identifies a key role for EZH2 in invasive melanoma cells

Oncogene, 2015-08, Vol.34 (33), p.4320-4332

2015

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A chemical biology screen reveals a role for Rab21-mediated control of actomyosin contractility in fibroblast-driven cancer invasion

British journal of cancer, 2010-01, Vol.102 (2), p.392-402

2010

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Imaging amoeboid cancer cell motility in vivo

Journal of microscopy (Oxford), 2008-09, Vol.231 (3), p.441-445

2008

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Development of an organotypic system for the study of cancer dormancy

European journal of cancer (1990), 2016-07, Vol.61, p.S109-S109

2016

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Mechanisms of cancer cell invasion

Current opinion in genetics & development, 2005-02, Vol.15 (1), p.87-96

Sahai, Erik

2005

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Autocrine IL-1β-TRAF6 signalling promotes squamous cell carcinoma invasion through paracrine TNFα signalling to carcinoma-associated fibroblasts

Oncogene, 2013-02, Vol.32 (6), p.747-758

2013

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YAP, Cdc42EP3 and septins modulate mechano-transduction and the emergence of cancer-associated fibroblasts

European journal of cancer (1990), 2016-07, Vol.61, p.S69-S70

2016

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Interaction between cancer associated fibroblasts and cancer cells influence immune infiltrate and is modulated by therapeutic agents

Annals of oncology, 2018-10, Vol.29, p.viii657-viii657

2018

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Cross-talk between Ras and Rho signalling pathways in transformation favours proliferation and increased motility

The EMBO journal, 2001-02, Vol.20 (4), p.755-766

2001

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Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I

Nature cell biology, 2001-04, Vol.3 (4), p.339-345

2001

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RhoA effector mutants reveal distinct effector pathways for cytoskeletal reorganization, SRF activation and transformation

The EMBO journal, 1998-03, Vol.17 (5), p.1350-1361

1998

Volltextzugriff (PDF)

Extracellular matrix anisotropy in breast cancer invasion and metastasis

European journal of cancer (1990), 2016-07, Vol.61, p.S102-S102

2016

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p120-catenin is required for the collective invasion of squamous cell carcinoma cells via a phosphorylation-independent mechanism

Oncogene, 2007-08, Vol.26 (36), p.5214-5228

2007

Volltextzugriff (PDF)

506 - Development of an organotypic system for the study of cancer dormancy

European journal of cancer (1990), 2016-07, Vol.61, p.S109-S109

2016

Volltextzugriff (PDF)

Integrin β1 is required for the invasive behaviour but not proliferation of squamous cell carcinoma cells in vivo

British journal of cancer, 2004-12, Vol.92 (1), p.102-112

2004

Volltextzugriff (PDF)

Rac Activation and Inactivation Control Plasticity of Tumor Cell Movement

Cell, 2008-10, Vol.135 (3), p.510-523

2008

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Regulation of Mitogen-Activated Protein Kinases in Cardiac Myocytes through the Small G Protein Rac1

Molecular and Cellular Biology, 2001-02, Vol.21 (4), p.1173-1184

2001

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Integrin signalling regulates YAP and TAZ to control skin homeostasis

Development (Cambridge), 2016-05, Vol.143 (10), p.1674-1687

2016

Volltextzugriff (PDF)

200 Breast Cancer-associated Fibroblasts Activated State is Regulated by Yes-associated Protein Activation Induced by Matrix Stiffness and Cytoskeletal Contractility

European journal of cancer (1990), 2012-07, Vol.48, p.S49-S49

2012

Volltextzugriff (PDF)

Differing modes of tumour cell invasion have distinct requirements for Rho/ROCK signalling and extracellular proteolysis

Nature cell biology, 2003-08, Vol.5 (8), p.711-719

2003

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1678P The interaction between cancer cells and cancer-associated fibroblasts promotes RAS signalling in squamous cell carcinoma, resulting in an immune-suppressive tumour microenvironment and poorer survival outcomes

Annals of oncology, 2022-09, Vol.33, p.S1309-S1310

2022

Volltextzugriff (PDF)

Understanding the microenvironment and how this controls cell fate

Developmental cell, 2023-12, Vol.58 (24), p.2819-2821

2023

Volltextzugriff (PDF)

RHO-GTPases and cancer

Nature reviews. Cancer, 2002-02, Vol.2 (2), p.133-142

2002

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ROCK and Dia have opposing effects on adherens junctions downstream of Rho

Nature cell biology, 2002-06, Vol.4 (6), p.408-415

2002

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35P Targeting the secreted gelsolin-DNGR-1 dendritic cell axis to enhance anti-cancer therapies

Annals of oncology, 2022-09, Vol.33, p.S557

2022

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Intravital imaging of SRF and Notch signalling identifies a key role for EZH2 in invasive melanoma cells

A chemical biology screen reveals a role for Rab21-mediated control of actomyosin contractility in fibroblast-driven cancer invasion

Imaging amoeboid cancer cell motility in vivo

Development of an organotypic system for the study of cancer dormancy

Mechanisms of cancer cell invasion

Autocrine IL-1β-TRAF6 signalling promotes squamous cell carcinoma invasion through paracrine TNFα signalling to carcinoma-associated fibroblasts

YAP, Cdc42EP3 and septins modulate mechano-transduction and the emergence of cancer-associated fibroblasts

Interaction between cancer associated fibroblasts and cancer cells influence immune infiltrate and is modulated by therapeutic agents

Cross-talk between Ras and Rho signalling pathways in transformation favours proliferation and increased motility

Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I

RhoA effector mutants reveal distinct effector pathways for cytoskeletal reorganization, SRF activation and transformation

Extracellular matrix anisotropy in breast cancer invasion and metastasis

p120-catenin is required for the collective invasion of squamous cell carcinoma cells via a phosphorylation-independent mechanism

506 - Development of an organotypic system for the study of cancer dormancy

Integrin β1 is required for the invasive behaviour but not proliferation of squamous cell carcinoma cells in vivo

Rac Activation and Inactivation Control Plasticity of Tumor Cell Movement

Regulation of Mitogen-Activated Protein Kinases in Cardiac Myocytes through the Small G Protein Rac1

Integrin signalling regulates YAP and TAZ to control skin homeostasis

200 Breast Cancer-associated Fibroblasts Activated State is Regulated by Yes-associated Protein Activation Induced by Matrix Stiffness and Cytoskeletal Contractility

Differing modes of tumour cell invasion have distinct requirements for Rho/ROCK signalling and extracellular proteolysis

1678P The interaction between cancer cells and cancer-associated fibroblasts promotes RAS signalling in squamous cell carcinoma, resulting in an immune-suppressive tumour microenvironment and poorer survival outcomes

Understanding the microenvironment and how this controls cell fate

RHO-GTPases and cancer

ROCK and Dia have opposing effects on adherens junctions downstream of Rho

35P Targeting the secreted gelsolin-DNGR-1 dendritic cell axis to enhance anti-cancer therapies

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