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Synthesis of spirocyclic tetrahydroisoquinolines (spiroTHIQs) via the Castagnoli-Cushman reaction

Tetrahedron letters, 2020-10, Vol.61 (42), p.152408, Article 152408

2020

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Three-component Castagnoli-Cushman reaction with ammonium acetate delivers 2-unsubstituted isoquinol-1-ones as potent inhibitors of poly(ADP-ribose) polymerase (PARP)

Journal of enzyme inhibition and medicinal chemistry, 2021-01, Vol.36 (1), p.1916-1921

2021

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1-Oxo-3,4-dihydroisoquinoline-4-carboxamides as novel druglike inhibitors of poly(ADP-ribose) polymerase (PARP) with favourable ADME characteristics

Journal of enzyme inhibition and medicinal chemistry, 2021-01, Vol.36 (1), p.1968-1983

2021

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Synthesis and chemical properties of 2-acylchromones

Russian chemical reviews, 2017-01, Vol.86 (4), p.318-338

2017

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One-Pot Domino Synthesis of Polyfunctionalized Benzophenones, Dihydroxanthones, and m-Terphenyls from 2-(Polyfluoroalkyl)chromones

European journal of organic chemistry, 2015-03, Vol.2015 (9), p.1932-1944

2015

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Self-condensation of 2-(ethoxalylmethyl)chromones into new derivatives of isotetronic acid

Mendeleev communications, 2018-07, Vol.28 (4), p.434-436

2018

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Synthesis of electron-deficient dienes bearing a chromonyl moiety via the reaction of 3-formylchromones with ylidenemalononitriles and ethyl α-cyano-β-methylcinnamate

Tetrahedron, 2014-06, Vol.70 (22), p.3584-3589

2014

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Novel method for the synthesis of 3-[(3-arylpyrazol-5-yl)methylidene]-quinoxalin-2-ones on the basis of 2-methylchromones

Chemistry of heterocyclic compounds (New York, N.Y. 1965), 2016-12, Vol.52 (12), p.1035-1041

2016

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Reactions of 2-(trifluoromethyl)chromones with cyanoacetamides, ethyl cyanoacetate and diethyl malonate. Unexpected synthesis of benzo[ c]coumarin derivatives

Tetrahedron letters, 2011-11, Vol.52 (47), p.6271-6274

2011

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Reactions of 2-(trifluoroacetyl)chromones with aromatic amines

Chemistry of heterocyclic compounds (New York, N.Y. 1965), 2017-12, Vol.53 (12), p.1362-1364

2017

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Synthesis of 4-arylamino-3-(trifluoromethyl)pyridazines and pyridazino[3,4-b]quinoxalines (as by-products) from 3-aroylmethyl-2-(trifluoromethyl)quinoxalines and hydrazine hydrate

RSC advances, 2016-01, Vol.6 (36), p.30056-30069

2016

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The reaction of ethyl 2-oxo-3-(4-oxo-4Н-chromen-2-yl)propanoates with S-methylisothiosemicarbazide hydroiodide

Chemistry of heterocyclic compounds (New York, N.Y. 1965), 2018-07, Vol.54 (7), p.696-699

2018

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α‐Diazo‐β‐oxosulfones as Partners in the Wolff 1,2,3‐Triazole Synthesis and the Wolff Rearrangement in the Presence of Aromatic Amines

European journal of organic chemistry, 2019-08, Vol.2019 (29), p.4721-4724

2019

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Reactions of 2-Methylchromones with Cyanoacetamides and Ethyl Cyanoacetate. Synthesis of 6-(2-Hydroxyaryl)-4-methyl-2-oxo-1,2-dihydropyridine-3-carbonitriles and 7-Hydroxy-6-imino-9-methyl-6H-benzo[c]chromene-8-carbonitriles

Journal of heterocyclic chemistry, 2013-09, Vol.50 (5), p.1005-1008

2013

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Zn(OTf)2-catalyzed, microwave-promoted synthesis of 2-substituted 5-methyloxazoles from propargylic amides

Tetrahedron letters, 2019-03, Vol.60 (11), p.777-779

2019

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Erratum to “Zn(OTf)2-catalyzed, microwave-promoted synthesis of 2-substituted 5-methyloxazoles from propargylic amides” [Tetrahedron Lett. 60 (2019) 777–779]

Tetrahedron letters, 2019-05, Vol.60 (20), p.1397-1398

2019

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Synthesis of a new class of carbinol linked bis-heterocycles via the reaction of 2-(trifluoroacetyl)chromones with indoles and pyrroles

Tetrahedron, 2016-01, Vol.72 (1), p.227-233

2016

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Exploration of the nitrogen heterocyclic periphery around the core of the advanced FFA1 agonist fasiglifam (TAK‐875)

Archiv der Pharmazie (Weinheim), 2021-04, Vol.354 (4), p.e2000275-n/a

2021

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Synthesis of 5-aryl-2-hydroxy-2-(trifluoromethyl)furan-3(2H)-ones and their reactions with aromatic 1,2-diamines, hydrazine and hydroxylamine

Tetrahedron, 2015-11, Vol.71 (45), p.8535-8543

2015

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Synthesis of 2-(trifluoroacetyl)chromones and their reactions with 1,2-diamines

Tetrahedron, 2015-03, Vol.71 (12), p.1822-1830

2015

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One-pot synthesis of functionalized benzo[c]coumarins and their precursors via the reaction of 2-(polyfluoroalkyl)chromones with 4-alkyl-3-cyanocoumarins

RSC advances, 2016, Vol.6 (63), p.58188-58202

2016

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Synthesis and reactivity of 8-aza-5,7-dimethyl-2-trifluoroacetylchromone

Chemistry of heterocyclic compounds (New York, N.Y. 1965), 2015-09, Vol.51 (9), p.838-844

2015

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Reactions of 2‐Methylchromones with Cyanoacetamides and Ethyl Cyanoacetate. Synthesis of 6‐(2‐Hydroxyaryl)‐4‐methyl‐2‐oxo‐1,2‐dihydropyridine‐3‐carbonitriles and 7‐Hydroxy‐6‐imino‐9‐methyl‐6 H ‐benzo[ c ]chromene‐8‐carbonitriles

Journal of heterocyclic chemistry, 2013-09, Vol.50 (5), p.1005-1008

2013

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One-pot synthesis of functionalized benzo[c]coumarins and their precursors via the reaction of 2-(polyfluoroalkyl)chromones with 4-alkyl-3-cyanocoumarinsElectronic supplementary information (ESI) available: Copies of 1H, 19F, and 13C NMR spectra of compounds obtained. CCDC 1465050, 1465067 and 1465073-1465075. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c6ra12492e

2016-06

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One-pot synthesis of functionalized benzo[c]coumarins and their precursors viathe reaction of 2-(polyfluoroalkyl)chromones with 4-alkyl-3-cyanocoumarins

RSC advances, 2016-06, Vol.6 (63), p.58188-58202

2016

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Synthesis of spirocyclic tetrahydroisoquinolines (spiroTHIQs) via the Castagnoli-Cushman reaction

Three-component Castagnoli-Cushman reaction with ammonium acetate delivers 2-unsubstituted isoquinol-1-ones as potent inhibitors of poly(ADP-ribose) polymerase (PARP)

1-Oxo-3,4-dihydroisoquinoline-4-carboxamides as novel druglike inhibitors of poly(ADP-ribose) polymerase (PARP) with favourable ADME characteristics

Synthesis and chemical properties of 2-acylchromones

One-Pot Domino Synthesis of Polyfunctionalized Benzophenones, Dihydroxanthones, and m-Terphenyls from 2-(Polyfluoroalkyl)chromones

Self-condensation of 2-(ethoxalylmethyl)chromones into new derivatives of isotetronic acid

Synthesis of electron-deficient dienes bearing a chromonyl moiety via the reaction of 3-formylchromones with ylidenemalononitriles and ethyl α-cyano-β-methylcinnamate

Novel method for the synthesis of 3-[(3-arylpyrazol-5-yl)methylidene]-quinoxalin-2-ones on the basis of 2-methylchromones

Reactions of 2-(trifluoromethyl)chromones with cyanoacetamides, ethyl cyanoacetate and diethyl malonate. Unexpected synthesis of benzo[ c]coumarin derivatives

Reactions of 2-(trifluoroacetyl)chromones with aromatic amines

Synthesis of 4-arylamino-3-(trifluoromethyl)pyridazines and pyridazino[3,4-b]quinoxalines (as by-products) from 3-aroylmethyl-2-(trifluoromethyl)quinoxalines and hydrazine hydrate

The reaction of ethyl 2-oxo-3-(4-oxo-4Н-chromen-2-yl)propanoates with S-methylisothiosemicarbazide hydroiodide

α‐Diazo‐β‐oxosulfones as Partners in the Wolff 1,2,3‐Triazole Synthesis and the Wolff Rearrangement in the Presence of Aromatic Amines

Reactions of 2-Methylchromones with Cyanoacetamides and Ethyl Cyanoacetate. Synthesis of 6-(2-Hydroxyaryl)-4-methyl-2-oxo-1,2-dihydropyridine-3-carbonitriles and 7-Hydroxy-6-imino-9-methyl-6H-benzo[c]chromene-8-carbonitriles

Zn(OTf)2-catalyzed, microwave-promoted synthesis of 2-substituted 5-methyloxazoles from propargylic amides

Erratum to “Zn(OTf)2-catalyzed, microwave-promoted synthesis of 2-substituted 5-methyloxazoles from propargylic amides” [Tetrahedron Lett. 60 (2019) 777–779]

Synthesis of a new class of carbinol linked bis-heterocycles via the reaction of 2-(trifluoroacetyl)chromones with indoles and pyrroles

Exploration of the nitrogen heterocyclic periphery around the core of the advanced FFA1 agonist fasiglifam (TAK‐875)

Synthesis of 5-aryl-2-hydroxy-2-(trifluoromethyl)furan-3(2H)-ones and their reactions with aromatic 1,2-diamines, hydrazine and hydroxylamine

Synthesis of 2-(trifluoroacetyl)chromones and their reactions with 1,2-diamines

One-pot synthesis of functionalized benzo[c]coumarins and their precursors via the reaction of 2-(polyfluoroalkyl)chromones with 4-alkyl-3-cyanocoumarins

Synthesis and reactivity of 8-aza-5,7-dimethyl-2-trifluoroacetylchromone

Reactions of 2‐Methylchromones with Cyanoacetamides and Ethyl Cyanoacetate. Synthesis of 6‐(2‐Hydroxyaryl)‐4‐methyl‐2‐oxo‐1,2‐dihydropyridine‐3‐carbonitriles and 7‐Hydroxy‐6‐imino‐9‐methyl‐6 H ‐benzo[ c ]chromene‐8‐carbonitriles

One-pot synthesis of functionalized benzo[c]coumarins and their precursors viathe reaction of 2-(polyfluoroalkyl)chromones with 4-alkyl-3-cyanocoumarins

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