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The edge effect: A global problem. The trouble with culturing cells in 96-well plates

Biochemistry and biophysics reports, 2021-07, Vol.26, p.100987-100987, Article 100987

2021

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Simple ammonium salts acting on sigma-1 receptors yield potential treatments for cancer and depression

Scientific reports, 2020-06, Vol.10 (1), p.9251-9251, Article 9251

2020

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Hazards of Using Masking Protocols When Performing Ligand Binding Assays: Lessons From the Sigma-1 and Sigma-2 Receptors

Frontiers in pharmacology, 2020-03, Vol.11, p.309-309

2020

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Editorial: Sigma Receptors

Frontiers in pharmacology, 2020-08, Vol.11, p.590519-590519

2020

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A cell-permeable tool for analysing APP intracellular domain function and manipulation of PIKfyve activity

Bioscience reports, 2016-04, Vol.36 (2)

2016

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An investigation of Sigma-1 receptor expression and ligand-induced endoplasmic reticulum stress in breast cancer

Cancer gene therapy, 2023-02, Vol.30 (2), p.368-374

2023

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Correction to: An investigation of Sigma-1 receptor expression and ligand-induced endoplasmic reticulum stress in breast cancer

Cancer gene therapy, 2023-02, Vol.30 (2), p.389-389

2023

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Dipentylammonium Binds to the Sigma-1 Receptor and Protects Against Glutamate Toxicity, Attenuates Dopamine Toxicity and Potentiates Neurite Outgrowth in Various Cultured Cell Lines

Neurotoxicity research, 2018-08, Vol.34 (2), p.263-272

2018

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A novel mechanism for the anticancer activity of aspirin and salicylates

International journal of oncology, 2019-04, Vol.54 (4), p.1256-1270

2019

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Characterizing Enzymes of the Diphosphoinositol Polyphosphate Phosphohydrolase (DIPP) Family

Methods in molecular biology (Clifton, N.J.), 2020, Vol.2091, p.75

2020

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Understanding inositol pyrophosphate metabolism and function: Kinetic characterization of the DIPPs

FEBS letters, 2013-11, Vol.587 (21), p.3464-3470

2013

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Nudix Hydrolases That Degrade Dinucleoside and Diphosphoinositol Polyphosphates Also Have 5-Phosphoribosyl 1-Pyrophosphate (PRPP) Pyrophosphatase Activity That Generates the Glycolytic Activator Ribose 1,5-Bisphosphate

The Journal of biological chemistry, 2002-12, Vol.277 (49), p.47313-47317

2002

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Sigma Receptors

2020

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Differential redox regulation within the PTP superfamily

Cellular signalling, 2007-07, Vol.19 (7), p.1521-1530

2007

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The g5R (D250) Gene of African Swine Fever Virus Encodes a Nudix Hydrolase That Preferentially Degrades Diphosphoinositol Polyphosphates

Journal of Virology, 2002-02, Vol.76 (3), p.1415-1421

2002

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Structural insights into the regulation of PDK1 by phosphoinositides and inositol phosphates

The EMBO journal, 2004-10, Vol.23 (20), p.3918-3928

2004

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Small molecule antagonists of the σ-1 receptor cause selective release of the death program in tumor and self-reliant cells and inhibit tumor growth in vitro and in vivo

Cancer research (Chicago, Ill.), 2004-07, Vol.64 (14), p.4875-4886

2004

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The Cytotoxicity and Synergistic Potential of Aspirin and Aspirin Analogues Towards Oesophageal and Colorectal Cancer

Current clinical pharmacology, 2019-01, Vol.14 (2), p.141-151

2019

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Visualization of inositol phosphate-dependent mobility of Ku: depletion of the DNA-PK cofactor InsP6 inhibits Ku mobility

Nucleic acids research, 2004, Vol.32 (9), p.2776-2784

2004

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Oxidation of the diphosphoinositol polyphosphate phosphohydrolase-like Nudix hydrolase Aps from Drosophila melanogaster induces thermolability—A possible regulatory switch?

The international journal of biochemistry & cell biology, 2010-07, Vol.42 (7), p.1174-1181

2010

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A novel context for the 'MutT' module, a guardian of cell integrity, in a diphosphoinositol polyphosphate phosphohydrolase

The EMBO journal, 1998-11, Vol.17 (22), p.6599-6607

1998

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Benzene Polyphosphates as Tools for Cell Signalling: Inhibition of Inositol 1,4,5-Trisphosphate 5-Phosphatase and Interaction with the PH Domain of Protein Kinase Bα

Chembiochem : a European journal of chemical biology, 2008-07, Vol.9 (11), p.1757-1766

2008

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PTEN M-CBR3, a versatile and selective regulator of inositol 1,3,4,5,6-pentakisphosphate (Ins(1,3,4,5,6)P5). Evidence for Ins(1,3,4,5,6)P5 as a proliferative signal

The Journal of biological chemistry, 2004-01, Vol.279 (2), p.1116-1122

2004

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Novel Inositol Phospholipid Headgroup Surrogate Crystallized in the Pleckstrin Homology Domain of Protein Kinase Bα

ACS chemical biology, 2007-04, Vol.2 (4), p.242-246

2007

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Characterisation of a bis(5′-nucleosyl)-tetraphosphatase (asymmetrical) from Drosophila melanogaster

The international journal of biochemistry & cell biology, 2007, Vol.39 (5), p.943-954

2007

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Inositol Phosphates - Metabolism
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The edge effect: A global problem. The trouble with culturing cells in 96-well plates

Simple ammonium salts acting on sigma-1 receptors yield potential treatments for cancer and depression

Hazards of Using Masking Protocols When Performing Ligand Binding Assays: Lessons From the Sigma-1 and Sigma-2 Receptors

Editorial: Sigma Receptors

A cell-permeable tool for analysing APP intracellular domain function and manipulation of PIKfyve activity

An investigation of Sigma-1 receptor expression and ligand-induced endoplasmic reticulum stress in breast cancer

Correction to: An investigation of Sigma-1 receptor expression and ligand-induced endoplasmic reticulum stress in breast cancer

Dipentylammonium Binds to the Sigma-1 Receptor and Protects Against Glutamate Toxicity, Attenuates Dopamine Toxicity and Potentiates Neurite Outgrowth in Various Cultured Cell Lines

A novel mechanism for the anticancer activity of aspirin and salicylates

Characterizing Enzymes of the Diphosphoinositol Polyphosphate Phosphohydrolase (DIPP) Family

Understanding inositol pyrophosphate metabolism and function: Kinetic characterization of the DIPPs

Nudix Hydrolases That Degrade Dinucleoside and Diphosphoinositol Polyphosphates Also Have 5-Phosphoribosyl 1-Pyrophosphate (PRPP) Pyrophosphatase Activity That Generates the Glycolytic Activator Ribose 1,5-Bisphosphate

Sigma Receptors

Differential redox regulation within the PTP superfamily

The g5R (D250) Gene of African Swine Fever Virus Encodes a Nudix Hydrolase That Preferentially Degrades Diphosphoinositol Polyphosphates

Structural insights into the regulation of PDK1 by phosphoinositides and inositol phosphates

Small molecule antagonists of the σ-1 receptor cause selective release of the death program in tumor and self-reliant cells and inhibit tumor growth in vitro and in vivo

The Cytotoxicity and Synergistic Potential of Aspirin and Aspirin Analogues Towards Oesophageal and Colorectal Cancer

Visualization of inositol phosphate-dependent mobility of Ku: depletion of the DNA-PK cofactor InsP6 inhibits Ku mobility

Oxidation of the diphosphoinositol polyphosphate phosphohydrolase-like Nudix hydrolase Aps from Drosophila melanogaster induces thermolability—A possible regulatory switch?

A novel context for the 'MutT' module, a guardian of cell integrity, in a diphosphoinositol polyphosphate phosphohydrolase

Benzene Polyphosphates as Tools for Cell Signalling: Inhibition of Inositol 1,4,5-Trisphosphate 5-Phosphatase and Interaction with the PH Domain of Protein Kinase Bα

PTEN M-CBR3, a versatile and selective regulator of inositol 1,3,4,5,6-pentakisphosphate (Ins(1,3,4,5,6)P5). Evidence for Ins(1,3,4,5,6)P5 as a proliferative signal

Novel Inositol Phospholipid Headgroup Surrogate Crystallized in the Pleckstrin Homology Domain of Protein Kinase Bα

Characterisation of a bis(5′-nucleosyl)-tetraphosphatase (asymmetrical) from Drosophila melanogaster

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