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Suppression of c‐Myc using 10058‐F4 exerts caspase‐3‐dependent apoptosis and intensifies the antileukemic effect of vincristine in pre‐B acute lymphoblastic leukemia cells

Journal of cellular biochemistry, 2019-08, Vol.120 (8), p.14004-14016

2019

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The PI3K/Akt/mTORC signaling axis in head and neck squamous cell carcinoma: Possibilities for therapeutic interventions either as single agents or in combination with conventional therapies

IUBMB life, 2021-04, Vol.73 (4), p.618-642

2021

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Anti‐leukemic effect of PI3K inhibition on chronic myeloid leukemia (CML) cells: shedding new light on the mitigating effect of c‐Myc and autophagy on BKM120 cytotoxicity

Cell biology international, 2020-05, Vol.44 (5), p.1212-1223

2020

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The PI3K/Akt signaling axis in Alzheimer’s disease: a valuable target to stimulate or suppress?

Cell stress & chaperones, 2021-11, Vol.26 (6), p.871-887

2021

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Small molecule inhibitor of c-Myc 10058-F4 inhibits proliferation and induces apoptosis in acute leukemia cells, irrespective of PTEN status

The international journal of biochemistry & cell biology, 2019-03, Vol.108, p.7-16

2019

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PI3K Abrogation Using Pan-PI3K Inhibitor BKM120 Gives Rise to a Significant Anticancer Effect on AML-Derived KG-1 Cells by Inducing Apoptosis and G2/M Arrest

Turkish journal of haematology, 2020-01, Vol.37 (3), p.167-176

2020

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Melatonin, an inhibitory agent in breast cancer

Breast cancer (Tokyo, Japan), 2017, Vol.24 (1), p.42-51

2017

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C-Myc inhibition sensitizes pre-B ALL cells to the anti-tumor effect of vincristine by altering apoptosis and autophagy: Proposing a probable mechanism of action for 10058-F4

European journal of pharmacology, 2020-03, Vol.870, p.172821-172821, Article 172821

2020

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ZnO/CNT@Fe3O4 induces ROS-mediated apoptosis in chronic myeloid leukemia (CML) cells: an emerging prospective for nanoparticles in leukemia treatment

Artificial cells, nanomedicine, and biotechnology, 2020-01, Vol.48 (1), p.735-745

2020

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Evaluation of hTERT, KRT7, and survivin in urine for noninvasive detection of bladder cancer using real-time PCR

BMC urology, 2021-04, Vol.21 (1), p.64-64, Article 64

2021

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Apoptin Overexpression Efficiently Amplified Cytotoxic Effects of PI3K Inhibition Using BKM120 in Lymphoblastic Leukemia Cell Lines

Advanced pharmaceutical bulletin, 2022-05, Vol.12 (3), p.613-622

2022

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Suppression of proteasome induces apoptosis in APL cells and increases chemo-sensitivity to arsenic trioxide: Proposing a perception in APL treatment

Cancer treatment and research communications, 2021, Vol.26, p.100284-100284, Article 100284

2021

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Pan-HDAC inhibitor panobinostat, as a single agent or in combination with PI3K inhibitor, induces apoptosis in APL cells: An emerging approach to overcome MSC-induced resistance

The international journal of biochemistry & cell biology, 2020-05, Vol.122, p.105734-105734, Article 105734

2020

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Stimulatory Effect of Indolic Hormone on As2O3 Cytotoxicity in Breast Cancer Cells: NF-κB-dependent Mechanism of Action of Melatonin

International journal of molecular and cellular medicine, 2018-01, Vol.7 (3), p.158-168

2018

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Phosphoinositide 3-kinase (PI3K) classes: From cell signaling to endocytic recycling and autophagy

European journal of pharmacology, 2023-08, Vol.953, p.175827-175827, Article 175827

2023

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The contributory role of lymphocyte subsets, pathophysiology of lymphopenia and its implication as prognostic and therapeutic opportunity in COVID-19

International immunopharmacology, 2021-06, Vol.95, p.107586-107586, Article 107586

2021

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Platelets in the perspective of COVID-19; pathophysiology of thrombocytopenia and its implication as prognostic and therapeutic opportunity

International immunopharmacology, 2021-10, Vol.99, p.107995-107995, Article 107995

2021

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The PI3K/Akt/mTOR signaling pathway in gastric cancer; from oncogenic variations to the possibilities for pharmacologic interventions

European journal of pharmacology, 2021-05, Vol.898, p.173983-173983, Article 173983

2021

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Kinase inhibitors: Opportunities for small molecule anticancer immunotherapies

Drug discovery today, 2023-05, Vol.28 (5), p.103525-103525, Article 103525

2023

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Inhibition of PI3K pathway using BKM120 intensified the chemo-sensitivity of breast cancer cells to arsenic trioxide (ATO)

The international journal of biochemistry & cell biology, 2019-11, Vol.116, p.105615-105615, Article 105615

2019

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Anticancer effect of pan-PI3K inhibitor on multiple myeloma cells: Shedding new light on the mechanisms involved in BKM120 resistance

European journal of pharmacology, 2019-01, Vol.842, p.89-98

2019

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Anti-leukemic effects of histone deacetylase (HDAC) inhibition in acute lymphoblastic leukemia (ALL) cells: Shedding light on mitigating effects of NF-κB and autophagy on panobinostat cytotoxicity

European journal of pharmacology, 2020-05, Vol.875, p.173050, Article 173050

2020

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Activation of PPARγ intensified the effects of arsenic trioxide in acute promyelocytic leukemia through the suppression of PI3K/Akt pathway: Proposing a novel anticancer effect for pioglitazone

The international journal of biochemistry & cell biology, 2020-05, Vol.122, p.105739-105739, Article 105739

2020

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c-Myc Inhibition Using 10058-F4 Increased the Sensitivity of Acute Promyelocytic Leukemia Cells to Arsenic Trioxide Via Blunting PI3K/NF-κB Axis

Archives of medical research, 2020-10, Vol.51 (7), p.636-644

2020

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Inhibition of PI3K signaling pathway enhances the chemosensitivity of APL cells to ATO: Proposing novel therapeutic potential for BKM120

European journal of pharmacology, 2018-12, Vol.841, p.10-18

2018

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Suppression of c‐Myc using 10058‐F4 exerts caspase‐3‐dependent apoptosis and intensifies the antileukemic effect of vincristine in pre‐B acute lymphoblastic leukemia cells

The PI3K/Akt/mTORC signaling axis in head and neck squamous cell carcinoma: Possibilities for therapeutic interventions either as single agents or in combination with conventional therapies

Anti‐leukemic effect of PI3K inhibition on chronic myeloid leukemia (CML) cells: shedding new light on the mitigating effect of c‐Myc and autophagy on BKM120 cytotoxicity

The PI3K/Akt signaling axis in Alzheimer’s disease: a valuable target to stimulate or suppress?

Small molecule inhibitor of c-Myc 10058-F4 inhibits proliferation and induces apoptosis in acute leukemia cells, irrespective of PTEN status

PI3K Abrogation Using Pan-PI3K Inhibitor BKM120 Gives Rise to a Significant Anticancer Effect on AML-Derived KG-1 Cells by Inducing Apoptosis and G2/M Arrest

Melatonin, an inhibitory agent in breast cancer

C-Myc inhibition sensitizes pre-B ALL cells to the anti-tumor effect of vincristine by altering apoptosis and autophagy: Proposing a probable mechanism of action for 10058-F4

ZnO/CNT@Fe3O4 induces ROS-mediated apoptosis in chronic myeloid leukemia (CML) cells: an emerging prospective for nanoparticles in leukemia treatment

Evaluation of hTERT, KRT7, and survivin in urine for noninvasive detection of bladder cancer using real-time PCR

Apoptin Overexpression Efficiently Amplified Cytotoxic Effects of PI3K Inhibition Using BKM120 in Lymphoblastic Leukemia Cell Lines

Suppression of proteasome induces apoptosis in APL cells and increases chemo-sensitivity to arsenic trioxide: Proposing a perception in APL treatment

Pan-HDAC inhibitor panobinostat, as a single agent or in combination with PI3K inhibitor, induces apoptosis in APL cells: An emerging approach to overcome MSC-induced resistance

Stimulatory Effect of Indolic Hormone on As2O3 Cytotoxicity in Breast Cancer Cells: NF-κB-dependent Mechanism of Action of Melatonin

Phosphoinositide 3-kinase (PI3K) classes: From cell signaling to endocytic recycling and autophagy

The contributory role of lymphocyte subsets, pathophysiology of lymphopenia and its implication as prognostic and therapeutic opportunity in COVID-19

Platelets in the perspective of COVID-19; pathophysiology of thrombocytopenia and its implication as prognostic and therapeutic opportunity

The PI3K/Akt/mTOR signaling pathway in gastric cancer; from oncogenic variations to the possibilities for pharmacologic interventions

Kinase inhibitors: Opportunities for small molecule anticancer immunotherapies

Inhibition of PI3K pathway using BKM120 intensified the chemo-sensitivity of breast cancer cells to arsenic trioxide (ATO)

Anticancer effect of pan-PI3K inhibitor on multiple myeloma cells: Shedding new light on the mechanisms involved in BKM120 resistance

Anti-leukemic effects of histone deacetylase (HDAC) inhibition in acute lymphoblastic leukemia (ALL) cells: Shedding light on mitigating effects of NF-κB and autophagy on panobinostat cytotoxicity

Activation of PPARγ intensified the effects of arsenic trioxide in acute promyelocytic leukemia through the suppression of PI3K/Akt pathway: Proposing a novel anticancer effect for pioglitazone

c-Myc Inhibition Using 10058-F4 Increased the Sensitivity of Acute Promyelocytic Leukemia Cells to Arsenic Trioxide Via Blunting PI3K/NF-κB Axis

Inhibition of PI3K signaling pathway enhances the chemosensitivity of APL cells to ATO: Proposing novel therapeutic potential for BKM120

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