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Resistance to Cell Death and Its Modulation in Cancer Stem Cells

Critical reviews in oncogenesis, 2016, Vol.21 (3-4), p.203-219

Safa, Ahmad R

2016

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Targeting the Anti-Apoptotic Protein c-FLIP for Cancer Therapy

Cancers, 2011-06, Vol.3 (2), p.1639-1671

2011

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c-FLIP knockdown induces ligand-independent DR5-, FADD-, caspase-8-, and caspase-9-dependent apoptosis in breast cancer cells

Biochemical pharmacology, 2008-12, Vol.76 (12), p.1694-1704

2008

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Taxol Induces Caspase-10-dependent Apoptosis

The Journal of biological chemistry, 2004-12, Vol.279 (49), p.51057-51067

2004

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Drug and apoptosis resistance in cancer stem cells (CSCs): A puzzle with many pieces

Cancer drug resistance, 2022-01, Vol.5 (4), p.850-72

Safa, Ahmad R.

2022

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Epithelial-mesenchymal transition: a hallmark in pancreatic cancer stem cell migration, metastasis formation, and drug resistance

Journal of cancer metastasis and treatment, 2020-01, Vol.2020

Safa, Ahmad R.

2020

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Glioblastoma stem cells (GSCs) epigenetic plasticity and interconversion between differentiated non-GSCs and GSCs

Genes & diseases, 2015-06, Vol.2 (2), p.152-163

2015

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Dynamic assessment of mitoxantrone resistance and modulation of multidrug resistance by valspodar (PSC833) in multidrug resistance human cancer cells

The Journal of pharmacology and experimental therapeutics, 2009-08, Vol.330 (2), p.423-429

2009

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Resistance to drugs and cell death in cancer stem cells (CSCs)

Journal of translational science, 2020-06, Vol.6 (3)

R Safa, Ahmad

2020

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RNA Helicase A in the MEF1 Transcription Factor Complex Up-regulates the MDR1 Gene in Multidrug-resistant Cancer Cells

The Journal of biological chemistry, 2004-04, Vol.279 (17), p.17134-17141

2004

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Roles of c-FLIP in Apoptosis, Necroptosis, and Autophagy

Journal of carcinogenesis & mutagenesis, 2013

R Safa, Ahmad

2013

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Cellular FLICE-like inhibitory protein (C-FLIP): a novel target for cancer therapy

Current cancer drug targets, 2008-02, Vol.8 (1), p.37-46

2008

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Sulforaphane suppresses the growth of glioblastoma cells, glioblastoma stem cell-like spheroids, and tumor xenografts through multiple cell signaling pathways

Journal of neurosurgery, 2017-12, Vol.127 (6), p.1219-1230

2017

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A Dose-escalation Study of Recombinant Human Interleukin-18 in Combination With Ofatumumab After Autologous Peripheral Blood Stem Cell Transplantation for Lymphoma

Journal of immunotherapy (1997), 2018-04, Vol.41 (3), p.151-157

2018

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c-FLIP Gene Silencing Eliminates Tumor Cells in Breast Cancer Xenografts Without Affecting Stromal Cells

Anticancer research, 2009-10, Vol.29 (10), p.3883-3886

2009

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Expression of the mutated p53 tumor suppressor protein and its molecular and biochemical characterization in multidrug resistant MCF-7/Adr human breast cancer cells

Oncogene, 1997-01, Vol.14 (4), p.499-506

1997

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Microarray Analysis Gene Expression Profiles in Laryngeal Muscle After Recurrent Laryngeal Nerve Injury

Annals of otology, rhinology & laryngology, 2016-03, Vol.125 (3), p.247-256

2016

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Identification and Characterization of the MDR1 Promoter-Enhancing Factor 1 (MEF1) in the Multidrug Resistant HL60/VCR Human Acute Myeloid Leukemia Cell Line

Biochemistry (Easton), 2000-01, Vol.39 (1), p.194-204

2000

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Potentiation of Carboplatin-Mediated DNA Damage by the Mdm2 Modulator Nutlin-3a in a Humanized Orthotopic Breast-to-Lung Metastatic Model

Molecular cancer therapeutics, 2015-12, Vol.14 (12), p.2850-2863

2015

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Emerging targets for glioblastoma stem cell therapy

Journal of biomedical research, 2016-01, Vol.30 (1), p.19-31

2016

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4-(4-Chloro-2-methylphenoxy)-N-hydroxybutanamide (CMH) targets mRNA of the c-FLIP variants and induces apoptosis in MCF-7 human breast cancer cells

Molecular and cellular biochemistry, 2010-09, Vol.342 (1-2), p.133-142

2010

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Human β-galactoside α-2,3-sialyltransferase (ST3Gal III) attenuated Taxol-induced apoptosis in ovarian cancer cells by downregulating caspase-8 activity

Molecular and cellular biochemistry, 2009-11, Vol.331 (1-2), p.81-88

2009

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A P-glycoprotein- and MRP1-independent Doxorubicin-resistant Variant of the MCF-7 Breast Cancer Cell Line with Defects in Caspase-6, -7, -8, -9 and -10 Activation Pathways

Anticancer research, 2004-01, Vol.24 (1), p.123-131

2004

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RNA interference in cancer: targeting the anti-apoptotic protein c-FLIP for drug discovery

Mini reviews in medicinal chemistry, 2009-06, Vol.9 (6), p.741-748

2009

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Cellular FLICE-like inhibitory protein (c-FLIP): A novel target for Taxol-induced apoptosis

Biochemical pharmacology, 2006-05, Vol.71 (11), p.1551-1561

2006

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Resistance to Cell Death and Its Modulation in Cancer Stem Cells

Targeting the Anti-Apoptotic Protein c-FLIP for Cancer Therapy

c-FLIP knockdown induces ligand-independent DR5-, FADD-, caspase-8-, and caspase-9-dependent apoptosis in breast cancer cells

Taxol Induces Caspase-10-dependent Apoptosis

Drug and apoptosis resistance in cancer stem cells (CSCs): A puzzle with many pieces

Epithelial-mesenchymal transition: a hallmark in pancreatic cancer stem cell migration, metastasis formation, and drug resistance

Glioblastoma stem cells (GSCs) epigenetic plasticity and interconversion between differentiated non-GSCs and GSCs

Dynamic assessment of mitoxantrone resistance and modulation of multidrug resistance by valspodar (PSC833) in multidrug resistance human cancer cells

Resistance to drugs and cell death in cancer stem cells (CSCs)

RNA Helicase A in the MEF1 Transcription Factor Complex Up-regulates the MDR1 Gene in Multidrug-resistant Cancer Cells

Roles of c-FLIP in Apoptosis, Necroptosis, and Autophagy

Cellular FLICE-like inhibitory protein (C-FLIP): a novel target for cancer therapy

Sulforaphane suppresses the growth of glioblastoma cells, glioblastoma stem cell-like spheroids, and tumor xenografts through multiple cell signaling pathways

A Dose-escalation Study of Recombinant Human Interleukin-18 in Combination With Ofatumumab After Autologous Peripheral Blood Stem Cell Transplantation for Lymphoma

c-FLIP Gene Silencing Eliminates Tumor Cells in Breast Cancer Xenografts Without Affecting Stromal Cells

Expression of the mutated p53 tumor suppressor protein and its molecular and biochemical characterization in multidrug resistant MCF-7/Adr human breast cancer cells

Microarray Analysis Gene Expression Profiles in Laryngeal Muscle After Recurrent Laryngeal Nerve Injury

Identification and Characterization of the MDR1 Promoter-Enhancing Factor 1 (MEF1) in the Multidrug Resistant HL60/VCR Human Acute Myeloid Leukemia Cell Line

Potentiation of Carboplatin-Mediated DNA Damage by the Mdm2 Modulator Nutlin-3a in a Humanized Orthotopic Breast-to-Lung Metastatic Model

Emerging targets for glioblastoma stem cell therapy

4-(4-Chloro-2-methylphenoxy)-N-hydroxybutanamide (CMH) targets mRNA of the c-FLIP variants and induces apoptosis in MCF-7 human breast cancer cells

Human β-galactoside α-2,3-sialyltransferase (ST3Gal III) attenuated Taxol-induced apoptosis in ovarian cancer cells by downregulating caspase-8 activity

A P-glycoprotein- and MRP1-independent Doxorubicin-resistant Variant of the MCF-7 Breast Cancer Cell Line with Defects in Caspase-6, -7, -8, -9 and -10 Activation Pathways

RNA interference in cancer: targeting the anti-apoptotic protein c-FLIP for drug discovery

Cellular FLICE-like inhibitory protein (c-FLIP): A novel target for Taxol-induced apoptosis

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