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Improving Immunotherapy Through Glycodesign

Frontiers in immunology, 2018-11, Vol.9, p.2485-2485

2018

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Exploiting metabolic glycoengineering to advance healthcare

Nature reviews. Chemistry, 2019-10, Vol.3 (10), p.605-620

2019

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Integration of genetic and metabolic features related to sialic acid metabolism distinguishes human breast cell subtypes

PloS one, 2018-05, Vol.13 (5), p.e0195812-e0195812

2018

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Determination of absolute expression profiles using multiplexed miRNA analysis

PloS one, 2017-07, Vol.12 (7), p.e0180988-e0180988

2017

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Improving the Pharmacodynamics and In Vivo Activity of ENPP1‐Fc Through Protein and Glycosylation Engineering

Clinical and translational science, 2021-01, Vol.14 (1), p.362-372

2021

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Glycoengineering Human Neural and Adipose Stem Cells with Novel Thiol-Modified N -Acetylmannosamine (ManNAc) Analogs

Cells (Basel, Switzerland), 2021-02, Vol.10 (2), p.377

2021

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Cell Line-, Protein-, and Sialoglycosite-Specific Control of Flux-Based Sialylation in Human Breast Cells: Implications for Cancer Progression

Frontiers in chemistry, 2020-02, Vol.8, p.13-13

2020

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Cell Surface and Membrane Engineering: Emerging Technologies and Applications

Journal of Functional Biomaterials, 2015-06, Vol.6 (2), p.454-485

2015

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Anticancer Properties of Hexosamine Analogs Designed to Attenuate Metabolic Flux through the Hexosamine Biosynthetic Pathway

ACS chemical biology, 2023-01, Vol.18 (1), p.151-165

2023

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Metabolic glycoengineering sensitizes drug-resistant pancreatic cancer cells to tyrosine kinase inhibitors erlotinib and gefitinib

Bioorganic & medicinal chemistry letters, 2015-03, Vol.25 (6), p.1223-1227

2015

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Metabolic flux-driven sialylation alters internalization, recycling, and drug sensitivity of the epidermal growth factor receptor (EGFR) in SW1990 pancreatic cancer cells

Oncotarget, 2016-10, Vol.7 (41), p.66491-66511

2016

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Pharmacological, Physiochemical, and Drug-Relevant Biological Properties of Short Chain Fatty Acid Hexosamine Analogues Used in Metabolic Glycoengineering

Molecular pharmaceutics, 2018-03, Vol.15 (3), p.705-720

2018

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Harnessing cancer cell metabolism for theranostic applications using metabolic glycoengineering of sialic acid in breast cancer as a pioneering example

Biomaterials, 2017-02, Vol.116, p.158-173

2017

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Combining Butyrated ManNAc with Glycoengineered CHO Cells Improves EPO Glycan Quality and Production

Biotechnology journal, 2019-04, Vol.14 (4), p.e1800186-n/a

2019

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Glycoengineering of Esterase Activity through Metabolic Flux‐Based Modulation of Sialic Acid

Chembiochem : a European journal of chemical biology, 2017-07, Vol.18 (13), p.1204-1215

2017

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Metabolic glycoengineering bacteria for therapeutic, recombinant protein, and metabolite production applications

Glycoconjugate journal, 2015-10, Vol.32 (7), p.425-441

2015

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General and efficient synthetic approach to novel tricyclic spiroketones

Tetrahedron, 2009-07, Vol.65 (27), p.5161-5167

2009

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Novel pyridine derivatives as potent and selective CB2 cannabinoid receptor agonists

Bioorganic & medicinal chemistry letters, 2009-10, Vol.19 (20), p.5931-5935

2009

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Abstract LB-054: Small molecule inhibitors of the hexosamine biosynthetic pathway and the cancer O-GlcNAcome

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.LB-054-LB-054

2016

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Novel sulfamoyl benzamides as selective CB2 agonists with improved in vitro metabolic stability

Bioorganic & medicinal chemistry letters, 2010, Vol.20 (1), p.387-391

2010

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Sulfamoyl benzamides as novel CB2 cannabinoid receptor ligands

Bioorganic & medicinal chemistry letters, 2008-05, Vol.18 (9), p.2830-2835

2008

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Discovery of N-(3-(morpholinomethyl)-phenyl)-amides as potent and selective CB2 agonists

Bioorganic & medicinal chemistry letters, 2009-09, Vol.19 (17), p.5004-5008

2009

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Novel pyridine derivatives as potent and selective CB sub(2) cannabinoid receptor agonists

Bioorganic & medicinal chemistry letters, 2009-10, Vol.19 (20), p.5931-5935

2009

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Discovery of N-(3-(morpholinomethyl)-phenyl)-amides as potent and selective CB sub(2) agonists

Bioorganic & medicinal chemistry letters, 2009-09, Vol.19 (17), p.5004-5008

2009

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Novel sulfamoyl benzamides as selective CB sub(2) agonists with improved in vitro metabolic stability

Bioorganic & medicinal chemistry letters, 2010-01, Vol.20 (1), p.387-391

2010

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Improving Immunotherapy Through Glycodesign

Exploiting metabolic glycoengineering to advance healthcare

Integration of genetic and metabolic features related to sialic acid metabolism distinguishes human breast cell subtypes

Determination of absolute expression profiles using multiplexed miRNA analysis

Improving the Pharmacodynamics and In Vivo Activity of ENPP1‐Fc Through Protein and Glycosylation Engineering

Glycoengineering Human Neural and Adipose Stem Cells with Novel Thiol-Modified N -Acetylmannosamine (ManNAc) Analogs

Cell Line-, Protein-, and Sialoglycosite-Specific Control of Flux-Based Sialylation in Human Breast Cells: Implications for Cancer Progression

Cell Surface and Membrane Engineering: Emerging Technologies and Applications

Anticancer Properties of Hexosamine Analogs Designed to Attenuate Metabolic Flux through the Hexosamine Biosynthetic Pathway

Metabolic glycoengineering sensitizes drug-resistant pancreatic cancer cells to tyrosine kinase inhibitors erlotinib and gefitinib

Metabolic flux-driven sialylation alters internalization, recycling, and drug sensitivity of the epidermal growth factor receptor (EGFR) in SW1990 pancreatic cancer cells

Pharmacological, Physiochemical, and Drug-Relevant Biological Properties of Short Chain Fatty Acid Hexosamine Analogues Used in Metabolic Glycoengineering

Harnessing cancer cell metabolism for theranostic applications using metabolic glycoengineering of sialic acid in breast cancer as a pioneering example

Combining Butyrated ManNAc with Glycoengineered CHO Cells Improves EPO Glycan Quality and Production

Glycoengineering of Esterase Activity through Metabolic Flux‐Based Modulation of Sialic Acid

Metabolic glycoengineering bacteria for therapeutic, recombinant protein, and metabolite production applications

General and efficient synthetic approach to novel tricyclic spiroketones

Novel pyridine derivatives as potent and selective CB2 cannabinoid receptor agonists

Abstract LB-054: Small molecule inhibitors of the hexosamine biosynthetic pathway and the cancer O-GlcNAcome

Novel sulfamoyl benzamides as selective CB2 agonists with improved in vitro metabolic stability

Sulfamoyl benzamides as novel CB2 cannabinoid receptor ligands

Discovery of N-(3-(morpholinomethyl)-phenyl)-amides as potent and selective CB2 agonists

Novel pyridine derivatives as potent and selective CB sub(2) cannabinoid receptor agonists

Discovery of N-(3-(morpholinomethyl)-phenyl)-amides as potent and selective CB sub(2) agonists

Novel sulfamoyl benzamides as selective CB sub(2) agonists with improved in vitro metabolic stability

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