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Histamine H3 receptor as a potential target for cognitive symptoms in neuropsychiatric diseases

Behavioural brain research, 2016-10, Vol.312, p.415-430

2016

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mTOR Signaling Disruption and Its Association with the Development of Autism Spectrum Disorder

Molecules (Basel, Switzerland), 2023-02, Vol.28 (4), p.1889

2023

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Role of Neuroinflammation in Autism Spectrum Disorder and the Emergence of Brain Histaminergic System. Lessons Also for BPSD?

Frontiers in pharmacology, 2020-06, Vol.11, p.886-886

2020

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Current Enlightenment About Etiology and Pharmacological Treatment of Autism Spectrum Disorder

Frontiers in neuroscience, 2018-05, Vol.12, p.304

2018

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In Vitro and In Vivo Antidiabetic Potential of Monoterpenoids: An Update

Molecules (Basel, Switzerland), 2021-12, Vol.27 (1), p.182

2021

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Repurposing SGLT2 Inhibitors for Neurological Disorders: A Focus on the Autism Spectrum Disorder

Molecules (Basel, Switzerland), 2022-10, Vol.27 (21), p.7174

2022

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Pharmacological and Molecular Insight on the Cardioprotective Role of Apigenin

Nutrients, 2023-01, Vol.15 (2), p.385

2023

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Plant Extracts and Phytochemicals Targeting α -Synuclein Aggregation in Parkinson's Disease Models

Frontiers in pharmacology, 2019-03, Vol.9, p.1555-1555

2019

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Anticonvulsant and procognitive properties of the non-imidazole histamine H3 receptor antagonist DL77 in male adult rats

Neuropharmacology, 2016-07, Vol.106, p.46-55

2016

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The histamine H3R antagonist DL77 attenuates autistic behaviors in a prenatal valproic acid-induced mouse model of autism

Scientific reports, 2018-08, Vol.8 (1), p.13077-15, Article 13077

2018

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A focused review on CB2 receptor-selective pharmacological properties and therapeutic potential of β-caryophyllene, a dietary cannabinoid

Biomedicine & pharmacotherapy, 2021-08, Vol.140, p.111639-111639, Article 111639

2021

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Simultaneous Antagonism at H3R/D2R/D3R Reduces Autism-like Self-Grooming and Aggressive Behaviors by Mitigating MAPK Activation in Mice

International journal of molecular sciences, 2022-12, Vol.24 (1), p.526

2022

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The Multi-Targeting Ligand ST-2223 with Histamine H3 Receptor and Dopamine D2/D3 Receptor Antagonist Properties Mitigates Autism-Like Repetitive Behaviors and Brain Oxidative Stress in Mice

International journal of molecular sciences, 2021-02, Vol.22 (4), p.1947

2021

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Therapeutic Potential of β-Caryophyllene: A Dietary Cannabinoid in Diabetes and Associated Complications

Nutrients, 2020-09, Vol.12 (10), p.2963

2020

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Canagliflozin Ameliorates Oxidative Stress and Autistic-like Features in Valproic-Acid-Induced Autism in Rats: Comparison with Aripiprazole Action

Pharmaceuticals (Basel, Switzerland), 2023-05, Vol.16 (5), p.769

2023

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Curcumin Potentiates α7 Nicotinic Acetylcholine Receptors and Alleviates Autistic-Like Social Deficits and Brain Oxidative Stress Status in Mice

International journal of molecular sciences, 2021-07, Vol.22 (14), p.7251

2021

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The Dual-Active Histamine H3 Receptor Antagonist and Acetylcholine Esterase Inhibitor E100 Alleviates Autistic-Like Behaviors and Oxidative Stress in Valproic Acid Induced Autism in Mice

International journal of molecular sciences, 2020-06, Vol.21 (11), p.3996

2020

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Repurposing Dimethyl Fumarate for Cardiovascular Diseases: Pharmacological Effects, Molecular Mechanisms, and Therapeutic Promise

Pharmaceuticals (Basel, Switzerland), 2022-04, Vol.15 (5), p.497

2022

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Antagonism of Histamine H3 receptors Alleviates Pentylenetetrazole-Induced Kindling and Associated Memory Deficits by Mitigating Oxidative Stress, Central Neurotransmitters, and c-Fos Protein Expression in Rats

Molecules (Basel, Switzerland), 2020-03, Vol.25 (7), p.1575

2020

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The Potent and Selective Histamine H3 Receptor Antagonist E169 Counteracts Cognitive Deficits and Mitigates Disturbances in the PI3K/AKT/GSK-3β Signaling Pathway in MK801-Induced Amnesia in Mice

International journal of molecular sciences, 2023-08, Vol.24 (16), p.12719

2023

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Role of Brain Modulators in Neurodevelopment: Focus on Autism Spectrum Disorder and Associated Comorbidities

Pharmaceuticals (Basel, Switzerland), 2022-05, Vol.15 (5), p.612

2022

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Plant-Derived Agents for Counteracting Cisplatin-Induced Nephrotoxicity

Oxidative medicine and cellular longevity, 2016-01, Vol.2016 (1), p.4320374-4320374

2016

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Experimental Studies Indicate That ST-2223, the Antagonist of Histamine H3 and Dopamine D2/D3 Receptors, Restores Social Deficits and Neurotransmission Dysregulation in Mouse Model of Autism

Pharmaceuticals (Basel, Switzerland), 2022-07, Vol.15 (8), p.929

2022

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Targeting Microglia in Neuroinflammation: H3 Receptor Antagonists as a Novel Therapeutic Approach for Alzheimer’s Disease, Parkinson’s Disease, and Autism Spectrum Disorder

Pharmaceuticals (Basel, Switzerland), 2024-06, Vol.17 (7), p.831

2024

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Simultaneous Blockade of Histamine H3 Receptors and Inhibition of Acetylcholine Esterase Alleviate Autistic-Like Behaviors in BTBR T+ tf/J Mouse Model of Autism

Biomolecules (Basel, Switzerland), 2020-08, Vol.10 (9), p.1251

2020

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Histamine H3 receptor as a potential target for cognitive symptoms in neuropsychiatric diseases

mTOR Signaling Disruption and Its Association with the Development of Autism Spectrum Disorder

Role of Neuroinflammation in Autism Spectrum Disorder and the Emergence of Brain Histaminergic System. Lessons Also for BPSD?

Current Enlightenment About Etiology and Pharmacological Treatment of Autism Spectrum Disorder

In Vitro and In Vivo Antidiabetic Potential of Monoterpenoids: An Update

Repurposing SGLT2 Inhibitors for Neurological Disorders: A Focus on the Autism Spectrum Disorder

Pharmacological and Molecular Insight on the Cardioprotective Role of Apigenin

Plant Extracts and Phytochemicals Targeting α -Synuclein Aggregation in Parkinson's Disease Models

Anticonvulsant and procognitive properties of the non-imidazole histamine H3 receptor antagonist DL77 in male adult rats

The histamine H3R antagonist DL77 attenuates autistic behaviors in a prenatal valproic acid-induced mouse model of autism

A focused review on CB2 receptor-selective pharmacological properties and therapeutic potential of β-caryophyllene, a dietary cannabinoid

Simultaneous Antagonism at H3R/D2R/D3R Reduces Autism-like Self-Grooming and Aggressive Behaviors by Mitigating MAPK Activation in Mice

The Multi-Targeting Ligand ST-2223 with Histamine H3 Receptor and Dopamine D2/D3 Receptor Antagonist Properties Mitigates Autism-Like Repetitive Behaviors and Brain Oxidative Stress in Mice

Therapeutic Potential of β-Caryophyllene: A Dietary Cannabinoid in Diabetes and Associated Complications

Canagliflozin Ameliorates Oxidative Stress and Autistic-like Features in Valproic-Acid-Induced Autism in Rats: Comparison with Aripiprazole Action

Curcumin Potentiates α7 Nicotinic Acetylcholine Receptors and Alleviates Autistic-Like Social Deficits and Brain Oxidative Stress Status in Mice

The Dual-Active Histamine H3 Receptor Antagonist and Acetylcholine Esterase Inhibitor E100 Alleviates Autistic-Like Behaviors and Oxidative Stress in Valproic Acid Induced Autism in Mice

Repurposing Dimethyl Fumarate for Cardiovascular Diseases: Pharmacological Effects, Molecular Mechanisms, and Therapeutic Promise

Antagonism of Histamine H3 receptors Alleviates Pentylenetetrazole-Induced Kindling and Associated Memory Deficits by Mitigating Oxidative Stress, Central Neurotransmitters, and c-Fos Protein Expression in Rats

The Potent and Selective Histamine H3 Receptor Antagonist E169 Counteracts Cognitive Deficits and Mitigates Disturbances in the PI3K/AKT/GSK-3β Signaling Pathway in MK801-Induced Amnesia in Mice

Role of Brain Modulators in Neurodevelopment: Focus on Autism Spectrum Disorder and Associated Comorbidities

Plant-Derived Agents for Counteracting Cisplatin-Induced Nephrotoxicity

Experimental Studies Indicate That ST-2223, the Antagonist of Histamine H3 and Dopamine D2/D3 Receptors, Restores Social Deficits and Neurotransmission Dysregulation in Mouse Model of Autism

Targeting Microglia in Neuroinflammation: H3 Receptor Antagonists as a Novel Therapeutic Approach for Alzheimer’s Disease, Parkinson’s Disease, and Autism Spectrum Disorder

Simultaneous Blockade of Histamine H3 Receptors and Inhibition of Acetylcholine Esterase Alleviate Autistic-Like Behaviors in BTBR T+ tf/J Mouse Model of Autism

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