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Small Molecule Inhibitors Targeting the Achilles' Heel of Androgen Receptor Activity

Cancer research (Chicago, Ill.), 2011-02, Vol.71 (4), p.1208-1213

SADAR, Marianne D

2011

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Discovery of drugs that directly target the intrinsically disordered region of the androgen receptor

Expert opinion on drug discovery, 2020-05, Vol.15 (5), p.551-560

Sadar, Marianne D.

2020

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Drugging the Undruggable: Targeting the N-Terminal Domain of Nuclear Hormone Receptors

Advances in experimental medicine and biology, 2022, Vol.1390, p.311-326

2022

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Androgen receptor targeted therapies in castration-resistant prostate cancer: Bench to clinic

International journal of urology, 2016-08, Vol.23 (8), p.654-665

2016

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Non-Genomic Actions of the Androgen Receptor in Prostate Cancer

Frontiers in endocrinology (Lausanne), 2017-01, Vol.8, p.2-2

2017

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Treatments Targeting the Androgen Receptor and Its Splice Variants in Breast Cancer

International journal of molecular sciences, 2024-02, Vol.25 (3), p.1817

2024

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Androgen receptor and its splice variants in prostate cancer

Cellular and molecular life sciences : CMLS, 2011-12, Vol.68 (24), p.3971-3981

2011

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Cyclin-dependent Kinase 4/6 Inhibitor Palbociclib in Combination with Ralaniten Analogs for the Treatment of Androgen Receptor-positive Prostate and Breast Cancers

Molecular cancer therapeutics, 2022-02, Vol.21 (2), p.294-309

2022

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Crosstalk between the androgen receptor and beta-catenin in castrate-resistant prostate cancer

Cancer research (Chicago, Ill.), 2008-12, Vol.68 (23), p.9918-9927

2008

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An androgen receptor N-terminal domain antagonist for treating prostate cancer

The Journal of clinical investigation, 2013-07, Vol.123 (7), p.2948-2960

2013

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Targeting the N‐Terminal Domain of the Androgen Receptor: A New Approach for the Treatment of Advanced Prostate Cancer

The oncologist (Dayton, Ohio), 2016-12, Vol.21 (12), p.1427-1435

2016

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Keys to unlock androgen receptor translocation

The Journal of biological chemistry, 2019-05, Vol.294 (22), p.8711-8712

2019

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Regression of Castrate-Recurrent Prostate Cancer by a Small-Molecule Inhibitor of the Amino-Terminus Domain of the Androgen Receptor

Cancer cell, 2010-06, Vol.17 (6), p.535-546

2010

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Combination therapy with androgen receptor N‐terminal domain antagonist EPI‐7170 and enzalutamide yields synergistic activity in AR‐V7‐positive prostate cancer

Molecular oncology, 2020-10, Vol.14 (10), p.2455-2470

2020

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Targeting Androgen Receptor Activation Function-1 with EPI to Overcome Resistance Mechanisms in Castration-Resistant Prostate Cancer

Clinical cancer research, 2016-09, Vol.22 (17), p.4466-4477

2016

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Cotargeting Androgen Receptor Splice Variants and mTOR Signaling Pathway for the Treatment of Castration-Resistant Prostate Cancer

Clinical cancer research, 2016-06, Vol.22 (11), p.2744-2754

2016

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Enzalutamide and blocking androgen receptor in advanced prostate cancer: lessons learnt from the history of drug development of antiandrogens

Research and reports in urology, 2018-01, Vol.10, p.23-32

2018

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LNCaP Atlas: gene expression associated with in vivo progression to castration-recurrent prostate cancer

BMC genomics, 2010-09, Vol.3 (1), p.43-43

2010

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Isolation and characterization of castration-resistant prostate cancer LNCaP95 clones

Human cell : official journal of Human Cell Research Society, 2021-01, Vol.34 (1), p.211-218

2021

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Identification of novel androgen-responsive genes by sequencing of LongSAGE libraries

BMC genomics, 2009-10, Vol.10 (1), p.476-476, Article 476

2009

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Inhibitors of the transactivation domain of androgen receptor as a therapy for prostate cancer

Steroids, 2024-10, Vol.210, p.109482, Article 109482

2024

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Advances in small molecule inhibitors of androgen receptor for the treatment of advanced prostate cancer

World journal of urology, 2012-06, Vol.30 (3), p.311-318

Sadar, Marianne D.

2012

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Order within a Disordered Structure

Structure (London), 2018-01, Vol.26 (1), p.4-6

2018

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Activation of the Androgen Receptor N-terminal Domain by Interleukin-6 via MAPK and STAT3 Signal Transduction Pathways

The Journal of biological chemistry, 2002-03, Vol.277 (9), p.7076-7085

2002

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Piperazate-Guided Isolation of Caveamides A and B, Cyclohexenylalanine-Containing Nonribosomal Peptides from a Cave Actinomycete

Organic letters, 2024-05, Vol.26 (19), p.4127-4131

2024

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Small Molecule Inhibitors Targeting the Achilles' Heel of Androgen Receptor Activity

Discovery of drugs that directly target the intrinsically disordered region of the androgen receptor

Drugging the Undruggable: Targeting the N-Terminal Domain of Nuclear Hormone Receptors

Androgen receptor targeted therapies in castration-resistant prostate cancer: Bench to clinic

Non-Genomic Actions of the Androgen Receptor in Prostate Cancer

Treatments Targeting the Androgen Receptor and Its Splice Variants in Breast Cancer

Androgen receptor and its splice variants in prostate cancer

Cyclin-dependent Kinase 4/6 Inhibitor Palbociclib in Combination with Ralaniten Analogs for the Treatment of Androgen Receptor-positive Prostate and Breast Cancers

Crosstalk between the androgen receptor and beta-catenin in castrate-resistant prostate cancer

An androgen receptor N-terminal domain antagonist for treating prostate cancer

Targeting the N‐Terminal Domain of the Androgen Receptor: A New Approach for the Treatment of Advanced Prostate Cancer

Keys to unlock androgen receptor translocation

Regression of Castrate-Recurrent Prostate Cancer by a Small-Molecule Inhibitor of the Amino-Terminus Domain of the Androgen Receptor

Combination therapy with androgen receptor N‐terminal domain antagonist EPI‐7170 and enzalutamide yields synergistic activity in AR‐V7‐positive prostate cancer

Targeting Androgen Receptor Activation Function-1 with EPI to Overcome Resistance Mechanisms in Castration-Resistant Prostate Cancer

Cotargeting Androgen Receptor Splice Variants and mTOR Signaling Pathway for the Treatment of Castration-Resistant Prostate Cancer

Enzalutamide and blocking androgen receptor in advanced prostate cancer: lessons learnt from the history of drug development of antiandrogens

LNCaP Atlas: gene expression associated with in vivo progression to castration-recurrent prostate cancer

Isolation and characterization of castration-resistant prostate cancer LNCaP95 clones

Identification of novel androgen-responsive genes by sequencing of LongSAGE libraries

Inhibitors of the transactivation domain of androgen receptor as a therapy for prostate cancer

Advances in small molecule inhibitors of androgen receptor for the treatment of advanced prostate cancer

Order within a Disordered Structure

Activation of the Androgen Receptor N-terminal Domain by Interleukin-6 via MAPK and STAT3 Signal Transduction Pathways

Piperazate-Guided Isolation of Caveamides A and B, Cyclohexenylalanine-Containing Nonribosomal Peptides from a Cave Actinomycete

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