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The NAD-dependent deacetylase SIRT2 is required for programmed necrosis

Nature (London), 2012-12, Vol.492 (7428), p.199-204

2012

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Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS)

The Journal of experimental medicine, 2011-03, Vol.208 (3), p.519-533

2011

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Characterization of the cardiac succinylome and its role in ischemia–reperfusion injury

Journal of molecular and cellular cardiology, 2015-11, Vol.88, p.73-81

2015

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Identification of a molecular component of the mitochondrial acetyltransferase programme: a novel role for GCN5L1

Biochemical journal, 2012-05, Vol.443 (3), p.655-661

2012

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Cysteine 203 of Cyclophilin D Is Critical for Cyclophilin D Activation of the Mitochondrial Permeability Transition Pore

The Journal of biological chemistry, 2011-11, Vol.286 (46), p.40184-40192

2011

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GCN5L1 modulates cross-talk between mitochondria and cell signaling to regulate FoxO1 stability and gluconeogenesis

Nature communications, 2017-09, Vol.8 (1), p.523-11, Article 523

2017

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Fasting and refeeding differentially regulate NLRP3 inflammasome activation in human subjects

The Journal of clinical investigation, 2015-12, Vol.125 (12), p.4592-4600

2015

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The Role of Mitochondria in the Pathophysiology of Skeletal Muscle Insulin Resistance

Endocrine reviews, 2010-02, Vol.31 (1), p.25-51

2010

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Fatty liver is associated with reduced SIRT3 activity and mitochondrial protein hyperacetylation

Biochemical journal, 2011-02, Vol.433 (3), p.505-514

2011

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Network Analysis and Transcriptome Profiling Identify Autophagic and Mitochondrial Dysfunctions in SARS-CoV-2 Infection

Frontiers in genetics, 2021-03, Vol.12, p.599261-599261

2021

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GCN5-like Protein 1 (GCN5L1) Controls Mitochondrial Content through Coordinated Regulation of Mitochondrial Biogenesis and Mitophagy

The Journal of biological chemistry, 2014-01, Vol.289 (5), p.2864-2872

2014

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Boosting NAD+ blunts TLR4-induced type I IFN in control and systemic lupus erythematosus monocytes

The Journal of clinical investigation, 2022-03, Vol.132 (5), p.1-14

2022

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Loss of GCN5L1 in cardiac cells disrupts glucose metabolism and promotes cell death via reduced Akt/mTORC2 signaling

Biochemical journal, 2019-06, Vol.476 (12), p.1713-1724

2019

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Immunometabolism at the Nexus of Cancer Therapeutic Efficacy and Resistance

Frontiers in immunology, 2021-05, Vol.12, p.657293-657293

2021

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Protein deacetylation by sirtuins: delineating a post-translational regulatory program responsive to nutrient and redox stressors

Cellular and molecular life sciences : CMLS, 2010-09, Vol.67 (18), p.3073-3087

2010

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Feeding-induced resistance to acute lethal sepsis is dependent on hepatic BMAL1 and FXR signalling

Nature communications, 2021-05, Vol.12 (1), p.2745-12, Article 2745

2021

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Nitrite augments tolerance to ischemia/reperfusion injury via the modulation of mitochondrial electron transfer

The Journal of experimental medicine, 2007-09, Vol.204 (9), p.2089-2102

2007

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Regulation of autophagy and mitophagy by nutrient availability and acetylation

Biochimica et biophysica acta, 2014-04, Vol.1841 (4), p.525-534

2014

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Allele-specific mitochondrial stress induced by Multiple Mitochondrial Dysfunctions Syndrome 1 pathogenic mutations modeled in Caenorhabditis elegans

PLoS genetics, 2021-08, Vol.17 (8), p.e1009771-e1009771

2021

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The complementary and divergent roles of uncoupling proteins 1 and 3 in thermoregulation

The Journal of physiology, 2016-12, Vol.594 (24), p.7455-7464

2016

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Cyclophilin D Modulates Mitochondrial Acetylome

Circulation research, 2013-12, Vol.113 (12), p.1308-1319

2013

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Restricted mitochondrial protein acetylation initiates mitochondrial autophagy

Journal of cell science, 2013-11, Vol.126 (Pt 21), p.4843-4849

2013

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Mitochondrial fidelity and metabolic agility control immune cell fate and function

The Journal of clinical investigation, 2018-09, Vol.128 (9), p.3651-3661

Sack, Michael N

2018

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Arachidonic acid inhibition of the NLRP3 inflammasome is a mechanism to explain the anti-inflammatory effects of fasting

Cell reports (Cambridge), 2024-02, Vol.43 (2), p.113700-113700, Article 113700

2024

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Targeting NAD+ Metabolism to Modulate Autoimmunity and Inflammation

The Journal of immunology (1950), 2024-04, Vol.212 (7), p.1043

2024

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The NAD-dependent deacetylase SIRT2 is required for programmed necrosis

Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS)

Characterization of the cardiac succinylome and its role in ischemia–reperfusion injury

Identification of a molecular component of the mitochondrial acetyltransferase programme: a novel role for GCN5L1

Cysteine 203 of Cyclophilin D Is Critical for Cyclophilin D Activation of the Mitochondrial Permeability Transition Pore

GCN5L1 modulates cross-talk between mitochondria and cell signaling to regulate FoxO1 stability and gluconeogenesis

Fasting and refeeding differentially regulate NLRP3 inflammasome activation in human subjects

The Role of Mitochondria in the Pathophysiology of Skeletal Muscle Insulin Resistance

Fatty liver is associated with reduced SIRT3 activity and mitochondrial protein hyperacetylation

Network Analysis and Transcriptome Profiling Identify Autophagic and Mitochondrial Dysfunctions in SARS-CoV-2 Infection

GCN5-like Protein 1 (GCN5L1) Controls Mitochondrial Content through Coordinated Regulation of Mitochondrial Biogenesis and Mitophagy

Boosting NAD+ blunts TLR4-induced type I IFN in control and systemic lupus erythematosus monocytes

Loss of GCN5L1 in cardiac cells disrupts glucose metabolism and promotes cell death via reduced Akt/mTORC2 signaling

Immunometabolism at the Nexus of Cancer Therapeutic Efficacy and Resistance

Protein deacetylation by sirtuins: delineating a post-translational regulatory program responsive to nutrient and redox stressors

Feeding-induced resistance to acute lethal sepsis is dependent on hepatic BMAL1 and FXR signalling

Nitrite augments tolerance to ischemia/reperfusion injury via the modulation of mitochondrial electron transfer

Regulation of autophagy and mitophagy by nutrient availability and acetylation

Allele-specific mitochondrial stress induced by Multiple Mitochondrial Dysfunctions Syndrome 1 pathogenic mutations modeled in Caenorhabditis elegans

The complementary and divergent roles of uncoupling proteins 1 and 3 in thermoregulation

Cyclophilin D Modulates Mitochondrial Acetylome

Restricted mitochondrial protein acetylation initiates mitochondrial autophagy

Mitochondrial fidelity and metabolic agility control immune cell fate and function

Arachidonic acid inhibition of the NLRP3 inflammasome is a mechanism to explain the anti-inflammatory effects of fasting

Targeting NAD+ Metabolism to Modulate Autoimmunity and Inflammation

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