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Suppression of the Epithelial–Mesenchymal Transition and Maintenance of the Liver Functions in Primary Hepatocytes through Dispersion Culture within a Dome-Shaped Collagen Matrix

Biological and Pharmaceutical Bulletin, 2024/07/01, Vol.47(7), pp.1241-1247

2024

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Comparative hepatotoxicity of a herbicide, epyrifenacil, in humans and rodents by comparing the dynamics and kinetics of its causal metabolite

Journal of Pesticide Science, 2021-11, Vol.46 (4), p.333-341, Article D21-026

2021

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Lack of human relevance for rat developmental toxicity of flumioxazin is revealed by comparative heme synthesis assay using embryonic erythroid cells derived from human and rat pluripotent stem cells

The Journal of Toxicological Sciences, 2022, Vol.47(4), pp.125-138

2022

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Elucidation of the species differences of epyrifenacil-induced hepatotoxicity between mice and humans by mass spectrometry imaging analysis in chimeric mice with humanized liver

The Journal of Toxicological Sciences, 2021, Vol.46(12), pp.601-609

2021

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Identification of the organic anion transporting polypeptides responsible for the hepatic uptake of the major metabolite of epyrifenacil, S‐3100‐CA, in mice

Pharmacology research & perspectives, 2021-10, Vol.9 (5), p.e00877-n/a

2021

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JaCVAM-organized international validation study of the in vivo rodent alkaline comet assay for detection of genotoxic carcinogens: II. Summary of definitive validation study results

Mutation research. Genetic toxicology and environmental mutagenesis, 2015-07, Vol.786-788, p.45-76

2015

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Increased susceptibility to hepatocarcinogenicity of Nrf2‐deficient mice exposed to 2‐amino‐3‐methylimidazo[4,5‐f]quinoline

Cancer science, 2007-01, Vol.98 (1), p.19-24

2007

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Enhanced sensitivity of chimeric insect olfactory co-receptors for detecting odorant molecules

Biochemical and biophysical research communications, 2024-09, Vol.726, p.150273, Article 150273

2024

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Absorption, Distribution, Metabolism, and Excretion of a New Herbicide, Epyrifenacil, in Rats

Journal of agricultural and food chemistry, 2021-11, Vol.69 (44), p.13190-13199

2021

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Novel approach for verification of a human PBPK modeling strategy using chimeric mice in the health risk assessment of epyrifenacil

Toxicology and applied pharmacology, 2023-04, Vol.465, p.116439-116439, Article 116439

2023

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Prediction of the human pharmacokinetics of epyrifenacil and its major metabolite, S-3100-CA, by a physiologically based pharmacokinetic modeling using chimeric mice with humanized liver

Toxicology and applied pharmacology, 2022-03, Vol.439, p.115912-115912, Article 115912

2022

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KOJIC ACID -ABSENCE OF TUMOR-INITIATING ACTIVITY IN RAT LIVER, AND OF CARCINOGENIC AND PHOTO-GENOTOXIC POTENTIAL IN MOUSE SKIN

The Journal of Toxicological Sciences, 2007, Vol.32(2), pp.143-159

2007

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Comparison of cytokine profiles in bronchoalveolar lavage fluid of mice exposed to respiratory and contact sensitizers

The Journal of Toxicological Sciences, 2012/04/01, Vol.37(2), pp.337-343

2012

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Lack of genotoxic potential of permethrin in mice evaluated by the comet assay and micronucleus test

Toxicological and environmental chemistry, 2018-01, Vol.100 (1), p.92-102

2018

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Club Cells Are the Primary Target for Permethrin-Induced Mouse Lung Tumor Formation

Toxicological sciences, 2021-10, Vol.184 (1), p.15-32

2021

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Assessment of the performance of the Ames MPF™ assay: A multicenter collaborative study with six coded chemicals

Mutation research. Genetic toxicology and environmental mutagenesis, 2024-01, Vol.893, p.503718-503718, Article 503718

2024

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Critical issues with the in vivo comet assay: A report of the comet assay working group in the 6th International Workshop on Genotoxicity Testing (IWGT)

Mutation research. Genetic toxicology and environmental mutagenesis, 2015-05, Vol.783, p.6-12

2015

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Genotoxicity evaluation of benzene, di(2-ethylhexyl) phthalate, and trisodium ethylenediamine tetraacetic acid monohydrate using a combined rat comet/micronucleus assays

Mutation research. Genetic toxicology and environmental mutagenesis, 2015-07, Vol.786-788, p.137-143

2015

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Optimal dose selection of N-methyl-N-nitrosourea for the rat comet assay to evaluate DNA damage in organs with different susceptibility to cytotoxicity

Mutation research. Genetic toxicology and environmental mutagenesis, 2015-07, Vol.786-788, p.129-136

2015

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Salmonella/human S9 mutagenicity test: a collaborative study with 58 compounds

Mutagenesis, 2005-05, Vol.20 (3), p.217-228

2005

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P-27. Development of a novel in vitro phototoxicity test method using human ES/iPS cells-derived retinal pigment epithelial cells for evaluation of UVB absorbers

Alternatives to Animal Testing and Experimentation, 2023-12, Vol.28 (suppl), p.126-126

2023

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Evaluation Report on Syrian Hamster Embryo Cell Transformation Assay

Alternatives to Animal Testing and Experimentation, 2023-09, Vol.28 (1), p.28-28

2023

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Evaluation Report on Syrian Hamster Embryo Cell Transformation Assay

Alternatives to Animal Testing and Experimentation, 2020-11, Vol.25 (1), p.34-35

2020

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Increased susceptibility to hepatocarcinogenicity of Nrf2-deficient mice exposed to 2-amino-3-methylimidazo4,5-fquinoline

Cancer science, 2007-01, Vol.98 (1), p.19

2007

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Suppression of the Epithelial–Mesenchymal Transition and Maintenance of the Liver Functions in Primary Hepatocytes through Dispersion Culture within a Dome-Shaped Collagen Matrix

Comparative hepatotoxicity of a herbicide, epyrifenacil, in humans and rodents by comparing the dynamics and kinetics of its causal metabolite

Lack of human relevance for rat developmental toxicity of flumioxazin is revealed by comparative heme synthesis assay using embryonic erythroid cells derived from human and rat pluripotent stem cells

Elucidation of the species differences of epyrifenacil-induced hepatotoxicity between mice and humans by mass spectrometry imaging analysis in chimeric mice with humanized liver

Identification of the organic anion transporting polypeptides responsible for the hepatic uptake of the major metabolite of epyrifenacil, S‐3100‐CA, in mice

JaCVAM-organized international validation study of the in vivo rodent alkaline comet assay for detection of genotoxic carcinogens: II. Summary of definitive validation study results

Increased susceptibility to hepatocarcinogenicity of Nrf2‐deficient mice exposed to 2‐amino‐3‐methylimidazo[4,5‐f]quinoline

Enhanced sensitivity of chimeric insect olfactory co-receptors for detecting odorant molecules

Absorption, Distribution, Metabolism, and Excretion of a New Herbicide, Epyrifenacil, in Rats

Novel approach for verification of a human PBPK modeling strategy using chimeric mice in the health risk assessment of epyrifenacil

Prediction of the human pharmacokinetics of epyrifenacil and its major metabolite, S-3100-CA, by a physiologically based pharmacokinetic modeling using chimeric mice with humanized liver

KOJIC ACID -ABSENCE OF TUMOR-INITIATING ACTIVITY IN RAT LIVER, AND OF CARCINOGENIC AND PHOTO-GENOTOXIC POTENTIAL IN MOUSE SKIN

Comparison of cytokine profiles in bronchoalveolar lavage fluid of mice exposed to respiratory and contact sensitizers

Lack of genotoxic potential of permethrin in mice evaluated by the comet assay and micronucleus test

Club Cells Are the Primary Target for Permethrin-Induced Mouse Lung Tumor Formation

Assessment of the performance of the Ames MPF™ assay: A multicenter collaborative study with six coded chemicals

Critical issues with the in vivo comet assay: A report of the comet assay working group in the 6th International Workshop on Genotoxicity Testing (IWGT)

Genotoxicity evaluation of benzene, di(2-ethylhexyl) phthalate, and trisodium ethylenediamine tetraacetic acid monohydrate using a combined rat comet/micronucleus assays

Generation and purification of ACTH-secreting hPSC-derived pituitary cells for effective transplantation

Optimal dose selection of N-methyl-N-nitrosourea for the rat comet assay to evaluate DNA damage in organs with different susceptibility to cytotoxicity

Salmonella/human S9 mutagenicity test: a collaborative study with 58 compounds

P-27. Development of a novel in vitro phototoxicity test method using human ES/iPS cells-derived retinal pigment epithelial cells for evaluation of UVB absorbers

Evaluation Report on Syrian Hamster Embryo Cell Transformation Assay

Evaluation Report on Syrian Hamster Embryo Cell Transformation Assay

Increased susceptibility to hepatocarcinogenicity of Nrf2-deficient mice exposed to 2-amino-3-methylimidazo4,5-fquinoline

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