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TIGIT Marks Exhausted T Cells, Correlates with Disease Progression, and Serves as a Target for Immune Restoration in HIV and SIV Infection

PLoS pathogens, 2016-01, Vol.12 (1), p.e1005349-e1005349

2016

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Human Galectin-9 Is a Potent Mediator of HIV Transcription and Reactivation

PLoS pathogens, 2016-06, Vol.12 (6), p.e1005677-e1005677

2016

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CCR5 inhibition in critical COVID-19 patients decreases inflammatory cytokines, increases CD8 T-cells, and decreases SARS-CoV2 RNA in plasma by day 14

International journal of infectious diseases, 2021-02, Vol.103, p.25-32

2021

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Improved delivery of broadly neutralizing antibodies by nanocapsules suppresses SHIV infection in the CNS of infant rhesus macaques

PLoS pathogens, 2021-07, Vol.17 (7), p.e1009738-e1009738

2021

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The human IL-15 superagonist N-803 promotes migration of virus-specific CD8+ T and NK cells to B cell follicles but does not reverse latency in ART-suppressed, SHIV-infected macaques

PLoS pathogens, 2020-03, Vol.16 (3), p.e1008339-e1008339

2020

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Comparison of the Superagonist Complex, ALT-803, to IL15 as Cancer Immunotherapeutics in Animal Models

Cancer immunology research, 2016-01, Vol.4 (1), p.49-60

2016

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Single-dose bNAb cocktail or abbreviated ART post-exposure regimens achieve tight SHIV control without adaptive immunity

Nature communications, 2020-01, Vol.11 (1), p.70-70, Article 70

2020

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Long-term hepatitis B virus infection of rhesus macaques requires suppression of host immunity

Nature communications, 2022-05, Vol.13 (1), p.2995-2995, Article 2995

2022

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Hepatocytic expression of human sodium-taurocholate cotransporting polypeptide enables hepatitis B virus infection of macaques

Nature communications, 2017-12, Vol.8 (1), p.2146-10, Article 2146

2017

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Cross-Species Rhesus Cytomegalovirus Infection of Cynomolgus Macaques

PLoS pathogens, 2016-11, Vol.12 (11), p.e1006014-e1006014

2016

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Natural Killer Cell Evasion Is Essential for Infection by Rhesus Cytomegalovirus

PLoS pathogens, 2016-08, Vol.12 (8), p.e1005868-e1005868

2016

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CCR5 Receptor Occupancy Analysis Reveals Increased Peripheral Blood CCR5+CD4+ T Cells Following Treatment With the Anti-CCR5 Antibody Leronlimab

Frontiers in immunology, 2021-11, Vol.12, p.794638-794638

2021

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Disruption of CCR5 signaling to treat COVID-19-associated cytokine storm: Case series of four critically ill patients treated with leronlimab

Journal of translational autoimmunity (Online), 2021-01, Vol.4, p.100083-100083, Article 100083

2021

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Rhesus Cytomegalovirus-Specific CD8 + Cytotoxic T Lymphocytes Do Not Become Functionally Exhausted in Chronic SIVmac239 Infection

Frontiers in immunology, 2020-08, Vol.11, p.1960

2020

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Efficacious Early Antiviral Activity of HIV Gag- and Pol-Specific HLA-B2705-Restricted CD8+ T Cells

Journal of Virology, 2010-10, Vol.84 (20), p.10543-10557

2010

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T cell inactivation by poxviral B22 family proteins increases viral virulence

PLoS pathogens, 2014-05, Vol.10 (5), p.e1004123-e1004123

2014

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Early Antigen Presentation of Protective HIV-1 KF11Gag and KK10Gag Epitopes from Incoming Viral Particles Facilitates Rapid Recognition of Infected Cells by Specific CD8+ T Cells

Journal of Virology, 2013-03, Vol.87 (5), p.2628-2638

2013

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Rapid Induction of Multifunctional Antibodies in Rabbits and Macaques by Clade C HIV-1 CAP257 Envelopes Circulating During Epitope-Specific Neutralization Breadth Development

Frontiers in immunology, 2020-06, Vol.11, p.984-984

2020

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Synchronous infection of SIV and HIV in vitro for virology, immunology and vaccine-related studies

Nature protocols, 2010-02, Vol.5 (2), p.239-246

2010

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Gag- and Nef-Specific CD4⁺ T Cells Recognize and Inhibit SIV Replication in Infected Macrophages Early after Infection

Proceedings of the National Academy of Sciences - PNAS, 2009-06, Vol.106 (24), p.9791-9796

2009

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The TRIM5α Genotype of Rhesus Macaques Affects Acquisition of Simian Immunodeficiency Virus SIVsmE660 Infection after Repeated Limiting-Dose Intrarectal Challenge

Journal of Virology, 2011-09, Vol.85 (18), p.9637-9640

2011

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Modified Adenovirus Prime-Protein Boost Clade C HIV Vaccine Strategy Results in Reduced Viral DNA in Blood and Tissues Following Tier 2 SHIV Challenge

Frontiers in immunology, 2021-02, Vol.11, p.626464-626464

2021

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TIGIT Marks Exhausted T Cells, Correlates with Disease Progression, and Serves as a Target for Immune Restoration in HIV and SIV Infection

Human Galectin-9 Is a Potent Mediator of HIV Transcription and Reactivation

CCR5 inhibition in critical COVID-19 patients decreases inflammatory cytokines, increases CD8 T-cells, and decreases SARS-CoV2 RNA in plasma by day 14

Improved delivery of broadly neutralizing antibodies by nanocapsules suppresses SHIV infection in the CNS of infant rhesus macaques

The human IL-15 superagonist N-803 promotes migration of virus-specific CD8+ T and NK cells to B cell follicles but does not reverse latency in ART-suppressed, SHIV-infected macaques

Comparison of the Superagonist Complex, ALT-803, to IL15 as Cancer Immunotherapeutics in Animal Models

Single-dose bNAb cocktail or abbreviated ART post-exposure regimens achieve tight SHIV control without adaptive immunity

Long-term hepatitis B virus infection of rhesus macaques requires suppression of host immunity

Hepatocytic expression of human sodium-taurocholate cotransporting polypeptide enables hepatitis B virus infection of macaques

Cytomegalovirus vaccine vector-induced effector memory CD4 + T cells protect cynomolgus macaques from lethal aerosolized heterologous avian influenza challenge

Suppression of human and simian immunodeficiency virus replication with the CCR5-specific antibody Leronlimab in two species

Cross-Species Rhesus Cytomegalovirus Infection of Cynomolgus Macaques

Natural Killer Cell Evasion Is Essential for Infection by Rhesus Cytomegalovirus

CCR5 Receptor Occupancy Analysis Reveals Increased Peripheral Blood CCR5+CD4+ T Cells Following Treatment With the Anti-CCR5 Antibody Leronlimab

Microbial Translocation and Inflammation Occur in Hyperacute Immunodeficiency Virus Infection and Compromise Host Control of Virus Replication

Disruption of CCR5 signaling to treat COVID-19-associated cytokine storm: Case series of four critically ill patients treated with leronlimab

Rhesus Cytomegalovirus-Specific CD8 + Cytotoxic T Lymphocytes Do Not Become Functionally Exhausted in Chronic SIVmac239 Infection

Efficacious Early Antiviral Activity of HIV Gag- and Pol-Specific HLA-B2705-Restricted CD8+ T Cells

T cell inactivation by poxviral B22 family proteins increases viral virulence

Early Antigen Presentation of Protective HIV-1 KF11Gag and KK10Gag Epitopes from Incoming Viral Particles Facilitates Rapid Recognition of Infected Cells by Specific CD8+ T Cells

Rapid Induction of Multifunctional Antibodies in Rabbits and Macaques by Clade C HIV-1 CAP257 Envelopes Circulating During Epitope-Specific Neutralization Breadth Development

Synchronous infection of SIV and HIV in vitro for virology, immunology and vaccine-related studies

Gag- and Nef-Specific CD4⁺ T Cells Recognize and Inhibit SIV Replication in Infected Macrophages Early after Infection

The TRIM5α Genotype of Rhesus Macaques Affects Acquisition of Simian Immunodeficiency Virus SIVsmE660 Infection after Repeated Limiting-Dose Intrarectal Challenge

Modified Adenovirus Prime-Protein Boost Clade C HIV Vaccine Strategy Results in Reduced Viral DNA in Blood and Tissues Following Tier 2 SHIV Challenge

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