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Mechanistic Investigation of Bone Marrow Suppression Associated with Palbociclib and its Differentiation from Cytotoxic Chemotherapies

Clinical cancer research, 2016-04, Vol.22 (8), p.2000-2008

2016

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CDK4/6 Inhibition on Glucose and Pancreatic Beta Cell Homeostasis in Young and Aged Rats

Molecular cancer research, 2017-11, Vol.15 (11), p.1531-1541

2017

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2-Methyl-6-(phenylethynyl)-pyridine (MPEP), a potent, selective and systemically active mGlu5 receptor antagonist

Neuropharmacology, 1999-10, Vol.38 (10), p.1493-1503

1999

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Pharmacological characterization of dopamine, norepinephrine and serotonin release in the rat prefrontal cortex by neuronal nicotinic acetylcholine receptor agonists

Brain research, 2003-11, Vol.990 (1), p.203-208

2003

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Pharmacological characterization of (S)-(2)-5-ethynyl-3-(1-methyl-2-pyrrolidinyl)pyridine HCl (SIB-1508Y, Altinicline), a novel nicotinic acetylcholine receptor agonist

Brain research, 2008-10, Vol.1234, p.16-24

2008

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An Approach to Early-Phase Salt Selection: Application to NBI-75043

Organic process research & development, 2007-05, Vol.11 (3), p.365-377

2007

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Activation of hippocampal metabotropic excitatory amino acid receptors leads to seizures and neuronal damage

Neuroscience letters, 1992-05, Vol.139 (1), p.77-82

1992

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(S)-(−)-5-Ethynyl-3-(1-methyl-2-pyrroli- dinyl)pyridine Maleate (SIB-1508Y): A Novel Anti-Parkinsonian Agent with Selectivity for Neuronal Nicotinic Acetylcholine Receptors

Journal of medicinal chemistry, 1996-08, Vol.39 (17), p.3235-3237

1996

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In vitro pharmacological characterization of (±)-4-[2-(1-methyl-2-pyrrolidinyl)ethyl]thio]phenol hydrochloride (SIB-1553A), a nicotinic acetylcholine receptor ligand

Brain research, 2003-08, Vol.981 (1), p.85-98

2003

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In vivo pharmacological characterization of (±)-4-[2-(1-methyl-2-pyrrolidinyl)ethyl]thiophenol hydrochloride (SIB-1553A), a novel cholinergic ligand: microdialysis studies

Brain research, 2003-10, Vol.986 (1), p.71-81

2003

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Pharmacological characterization of SIB-1663, a conformationally rigid analog of nicotine

Brain research, 2004-04, Vol.1003 (1), p.42-53

2004

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4-[[2-(1-Methyl-2-pyrrolidinyl)ethyl]thio]- phenol Hydrochloride (SIB-1553A): A Novel Cognitive Enhancer with Selectivity for Neuronal Nicotinic Acetylcholine Receptors

Journal of medicinal chemistry, 1999-05, Vol.42 (10), p.1684-1686

1999

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Pharmacological characterization of SIB-1765F: a novel cholinergic ion channel agonist

The Journal of pharmacology and experimental therapeutics, 1997-01, Vol.280 (1), p.373

1997

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6-hydroxydopamine lesion of rat nigrostriatal dopaminergic neurons differentially affects nicotinic acetylcholine receptor subunit mRNA expression

Journal of molecular neuroscience, 1998-06, Vol.10 (3), p.251-260

1998

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Metabotropic Glutamate Receptor Activation Produces Extrapyramidal Motor System Activation That Is Mediated by Striatal Dopamine

Journal of neurochemistry, 1992-07, Vol.59 (1), p.245-251

1992

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Epibatidine: a nicotinic acetylcholine receptor agonist releases monoaminergic neurotransmitters: in vitro and in vivo evidence in rats

The Journal of pharmacology and experimental therapeutics, 1996-02, Vol.276 (2), p.509

1996

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Conformationally restricted analogues of nicotine and anabasine

Bioorganic & medicinal chemistry letters, 1998-08, Vol.8 (16), p.2173-2178

1998

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Characterization of the stimulatory and inhibitory effects of polyamines on [3H]N-(1-[thienyl]cyclohexyl) piperidine binding to the N-methyl-D-aspartate receptor ionophore complex

Molecular pharmacology, 1990-04, Vol.37 (4), p.572-577

1990

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(S)-4-carboxy-3-hydroxyphenylglycine activates phosphatidyl inositol linked metabotropic glutamate receptors in different brain regions of the neonatal rat

Neurochemistry international, 1998, Vol.32 (1), p.77-85

1998

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Metabotropic glutamate receptors and neuronal degenerative disorders

Neurobiology of aging, 1994-03, Vol.15 (2), p.261-263

1994

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D,L-(Tetrazol-5-yl) glycine: a novel and highly potent NMDA receptor agonist

European journal of pharmacology, 1991-10, Vol.203 (2), p.237-243

1991

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Competitive inhibition of magnesium-induced [3H]N-(1-[thienyl] cyclohexyl)piperidine binding by arcaine: evidence for a shared spermidine-magnesium binding site

Molecular pharmacology, 1990-11, Vol.38 (5), p.705-710

1990

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Regulation of polyamine and magnesium inhibition of the [formula omitted] (NMDA) receptor ionophore complex

Neuroscience letters, 1991, Vol.121 (1), p.219-222

1991

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Equilibrium analysis of [ 3H]TCP binding: effects of glycine, magnesium and N-methyl-D-aspartate agonists

European journal of pharmacology, 1988-07, Vol.152 (1), p.141-146

1988

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Regulation of polyamine and magnesium inhibition of the N-methyl-D-aspartate (NMDA) receptor ionophore complex

Neuroscience letters, 1991-01, Vol.121 (1-2), p.219-222

1991

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Mechanistic Investigation of Bone Marrow Suppression Associated with Palbociclib and its Differentiation from Cytotoxic Chemotherapies

CDK4/6 Inhibition on Glucose and Pancreatic Beta Cell Homeostasis in Young and Aged Rats

2-Methyl-6-(phenylethynyl)-pyridine (MPEP), a potent, selective and systemically active mGlu5 receptor antagonist

Pharmacological characterization of dopamine, norepinephrine and serotonin release in the rat prefrontal cortex by neuronal nicotinic acetylcholine receptor agonists

Pharmacological characterization of (S)-(2)-5-ethynyl-3-(1-methyl-2-pyrrolidinyl)pyridine HCl (SIB-1508Y, Altinicline), a novel nicotinic acetylcholine receptor agonist

An Approach to Early-Phase Salt Selection: Application to NBI-75043

Activation of hippocampal metabotropic excitatory amino acid receptors leads to seizures and neuronal damage

(S)-(−)-5-Ethynyl-3-(1-methyl-2-pyrroli- dinyl)pyridine Maleate (SIB-1508Y): A Novel Anti-Parkinsonian Agent with Selectivity for Neuronal Nicotinic Acetylcholine Receptors

In vitro pharmacological characterization of (±)-4-[2-(1-methyl-2-pyrrolidinyl)ethyl]thio]phenol hydrochloride (SIB-1553A), a nicotinic acetylcholine receptor ligand

In vivo pharmacological characterization of (±)-4-[2-(1-methyl-2-pyrrolidinyl)ethyl]thiophenol hydrochloride (SIB-1553A), a novel cholinergic ligand: microdialysis studies

Pharmacological characterization of SIB-1663, a conformationally rigid analog of nicotine

4-[[2-(1-Methyl-2-pyrrolidinyl)ethyl]thio]- phenol Hydrochloride (SIB-1553A): A Novel Cognitive Enhancer with Selectivity for Neuronal Nicotinic Acetylcholine Receptors

Pharmacological characterization of SIB-1765F: a novel cholinergic ion channel agonist

6-hydroxydopamine lesion of rat nigrostriatal dopaminergic neurons differentially affects nicotinic acetylcholine receptor subunit mRNA expression

Metabotropic Glutamate Receptor Activation Produces Extrapyramidal Motor System Activation That Is Mediated by Striatal Dopamine

Epibatidine: a nicotinic acetylcholine receptor agonist releases monoaminergic neurotransmitters: in vitro and in vivo evidence in rats

Conformationally restricted analogues of nicotine and anabasine

Characterization of the stimulatory and inhibitory effects of polyamines on [3H]N-(1-[thienyl]cyclohexyl) piperidine binding to the N-methyl-D-aspartate receptor ionophore complex

(S)-4-carboxy-3-hydroxyphenylglycine activates phosphatidyl inositol linked metabotropic glutamate receptors in different brain regions of the neonatal rat

Metabotropic glutamate receptors and neuronal degenerative disorders

D,L-(Tetrazol-5-yl) glycine: a novel and highly potent NMDA receptor agonist

Competitive inhibition of magnesium-induced [3H]N-(1-[thienyl] cyclohexyl)piperidine binding by arcaine: evidence for a shared spermidine-magnesium binding site

Regulation of polyamine and magnesium inhibition of the [formula omitted] (NMDA) receptor ionophore complex

Equilibrium analysis of [ 3H]TCP binding: effects of glycine, magnesium and N-methyl-D-aspartate agonists

Regulation of polyamine and magnesium inhibition of the N-methyl-D-aspartate (NMDA) receptor ionophore complex

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