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Reproductive and developmental toxicity assessment of palbociclib, a CDK4/6 inhibitor, in Sprague-Dawley rats and New Zealand White rabbits

Reproductive toxicology (Elmsford, N.Y.), 2019-09, Vol.88, p.76-84

2019

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2-Methyl-6-(phenylethynyl)-pyridine (MPEP), a potent, selective and systemically active mGlu5 receptor antagonist

Neuropharmacology, 1999-10, Vol.38 (10), p.1493-1503

1999

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Pharmacological characterization of neuronal acetylcholine gated ion channel receptor-mediated hippocampal norepinephrine and striatal dopamine release from rat brain slices

The Journal of pharmacology and experimental therapeutics, 1995-07, Vol.274 (1), p.224

1995

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354P Synergistic preclinical efficacy through combination of the CDK4 and CDK2 selective inhibitors, PF-07220060 and PF-07104091, respectively, in HR+ HER2- breast cancer

Annals of oncology, 2024-09, Vol.35, p.S365-S365

2024

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Activation of hippocampal metabotropic excitatory amino acid receptors leads to seizures and neuronal damage

Neuroscience letters, 1992-05, Vol.139 (1), p.77-82

1992

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Developmental and reproductive toxicity studies in Sprague-Dawley rats and New Zealand white rabbits with palbociclib

Reproductive toxicology (Elmsford, N.Y.), 2019-09, Vol.88, p.29-29

2019

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Cloning and stable expression of the mGluR1b subtype of human metabotropic receptors and pharmacological comparison with the mGluR5a subtype

Neuropharmacology, 1997-07, Vol.36 (7), p.917-931

1997

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Metabotropic Glutamate Receptor Activation Produces Extrapyramidal Motor System Activation That Is Mediated by Striatal Dopamine

Journal of neurochemistry, 1992-07, Vol.59 (1), p.245-251

1992

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4-[[2-(1-Methyl-2-pyrrolidinyl)ethyl]thio]- phenol Hydrochloride (SIB-1553A): A Novel Cognitive Enhancer with Selectivity for Neuronal Nicotinic Acetylcholine Receptors

Journal of medicinal chemistry, 1999-05, Vol.42 (10), p.1684-1686

1999

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Intrastriatal injection of a selective metabotropic excitatory amino acid receptor agonist induces contralateral turning in the rat

The Journal of pharmacology and experimental therapeutics, 1991-12, Vol.259 (3), p.1366

1991

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Molecular and functional characterization of recombinant human metabotropic glutamate receptor subtype 5

Neuropharmacology, 1995-08, Vol.34 (8), p.871-886

1995

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The potential of subtype-selective neuronal nicotinic acetylcholine receptor agonists as therapeutic agents

Life sciences (1973), 1998, Vol.62 (17), p.1601-1606

1998

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Spermine enhances binding to the glycine site associated with the N-methyl-D-aspartate receptor complex

Molecular pharmacology, 1989-12, Vol.36 (6), p.836-839

1989

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Characterization of the stimulatory and inhibitory effects of polyamines on [3H]N-(1-[thienyl]cyclohexyl) piperidine binding to the N-methyl-D-aspartate receptor ionophore complex

Molecular pharmacology, 1990-04, Vol.37 (4), p.572-577

1990

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Conformationally restricted analogues of nicotine and anabasine

Bioorganic & medicinal chemistry letters, 1998-08, Vol.8 (16), p.2173-2178

1998

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(S)-4-carboxy-3-hydroxyphenylglycine activates phosphatidyl inositol linked metabotropic glutamate receptors in different brain regions of the neonatal rat

Neurochemistry international, 1998, Vol.32 (1), p.77-85

1998

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Epibatidine: a nicotinic acetylcholine receptor agonist releases monoaminergic neurotransmitters: in vitro and in vivo evidence in rats

The Journal of pharmacology and experimental therapeutics, 1996-02, Vol.276 (2), p.509

1996

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(S)-(−)-5-Ethynyl-3-(1-methyl-2-pyrroli- dinyl)pyridine Maleate (SIB-1508Y): A Novel Anti-Parkinsonian Agent with Selectivity for Neuronal Nicotinic Acetylcholine Receptors

Journal of medicinal chemistry, 1996-08, Vol.39 (17), p.3235-3237

1996

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Pharmacological profile of NPC 12626, a novel, competitive N-methyl-D-aspartate receptor antagonist

The Journal of pharmacology and experimental therapeutics, 1989-07, Vol.250 (1), p.100

1989

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Spermidine reverses arcaine's inhibition of N-methyl-D-aspartate-induced hippocampal [3H]norepinephrine release

The Journal of pharmacology and experimental therapeutics, 1990-12, Vol.255 (3), p.1060

1990

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Competitive inhibition of magnesium-induced [3H]N-(1-[thienyl] cyclohexyl)piperidine binding by arcaine: evidence for a shared spermidine-magnesium binding site

Molecular pharmacology, 1990-11, Vol.38 (5), p.705-710

1990

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Metabotropic glutamate receptors and neuronal degenerative disorders

Neurobiology of aging, 1994-03, Vol.15 (2), p.261-263

1994

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SIB-1757 and SIB-1893: selective, noncompetitive antagonists of metabotropic glutamate receptor type 5

The Journal of pharmacology and experimental therapeutics, 1999-07, Vol.290 (1), p.170

1999

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D,L-(Tetrazol-5-yl) glycine: a novel and highly potent NMDA receptor agonist

European journal of pharmacology, 1991-10, Vol.203 (2), p.237-243

1991

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Pharmacological characterization of SIB-1765F: a novel cholinergic ion channel agonist

The Journal of pharmacology and experimental therapeutics, 1997-01, Vol.280 (1), p.373

1997

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Reproductive and developmental toxicity assessment of palbociclib, a CDK4/6 inhibitor, in Sprague-Dawley rats and New Zealand White rabbits

2-Methyl-6-(phenylethynyl)-pyridine (MPEP), a potent, selective and systemically active mGlu5 receptor antagonist

Pharmacological characterization of neuronal acetylcholine gated ion channel receptor-mediated hippocampal norepinephrine and striatal dopamine release from rat brain slices

354P Synergistic preclinical efficacy through combination of the CDK4 and CDK2 selective inhibitors, PF-07220060 and PF-07104091, respectively, in HR+ HER2- breast cancer

Activation of hippocampal metabotropic excitatory amino acid receptors leads to seizures and neuronal damage

Developmental and reproductive toxicity studies in Sprague-Dawley rats and New Zealand white rabbits with palbociclib

Cloning and stable expression of the mGluR1b subtype of human metabotropic receptors and pharmacological comparison with the mGluR5a subtype

Metabotropic Glutamate Receptor Activation Produces Extrapyramidal Motor System Activation That Is Mediated by Striatal Dopamine

4-[[2-(1-Methyl-2-pyrrolidinyl)ethyl]thio]- phenol Hydrochloride (SIB-1553A): A Novel Cognitive Enhancer with Selectivity for Neuronal Nicotinic Acetylcholine Receptors

Intrastriatal injection of a selective metabotropic excitatory amino acid receptor agonist induces contralateral turning in the rat

Molecular and functional characterization of recombinant human metabotropic glutamate receptor subtype 5

The potential of subtype-selective neuronal nicotinic acetylcholine receptor agonists as therapeutic agents

Spermine enhances binding to the glycine site associated with the N-methyl-D-aspartate receptor complex

Characterization of the stimulatory and inhibitory effects of polyamines on [3H]N-(1-[thienyl]cyclohexyl) piperidine binding to the N-methyl-D-aspartate receptor ionophore complex

Conformationally restricted analogues of nicotine and anabasine

(S)-4-carboxy-3-hydroxyphenylglycine activates phosphatidyl inositol linked metabotropic glutamate receptors in different brain regions of the neonatal rat

Epibatidine: a nicotinic acetylcholine receptor agonist releases monoaminergic neurotransmitters: in vitro and in vivo evidence in rats

(S)-(−)-5-Ethynyl-3-(1-methyl-2-pyrroli- dinyl)pyridine Maleate (SIB-1508Y): A Novel Anti-Parkinsonian Agent with Selectivity for Neuronal Nicotinic Acetylcholine Receptors

Pharmacological profile of NPC 12626, a novel, competitive N-methyl-D-aspartate receptor antagonist

Spermidine reverses arcaine's inhibition of N-methyl-D-aspartate-induced hippocampal [3H]norepinephrine release

Competitive inhibition of magnesium-induced [3H]N-(1-[thienyl] cyclohexyl)piperidine binding by arcaine: evidence for a shared spermidine-magnesium binding site

Metabotropic glutamate receptors and neuronal degenerative disorders

SIB-1757 and SIB-1893: selective, noncompetitive antagonists of metabotropic glutamate receptor type 5

D,L-(Tetrazol-5-yl) glycine: a novel and highly potent NMDA receptor agonist

Pharmacological characterization of SIB-1765F: a novel cholinergic ion channel agonist

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