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The quiescent endothelium: signalling pathways regulating organ-specific endothelial normalcy

Nature reviews cardiology, 2021-08, Vol.18 (8), p.565-580

2021

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Deciphering the complex role of thrombospondin-1 in glioblastoma development

Nature communications, 2019-03, Vol.10 (1), p.1146-1146, Article 1146

2019

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Bone Morphogenetic Proteins in Vascular Homeostasis and Disease

Cold Spring Harbor perspectives in biology, 2018-02, Vol.10 (2), p.a031989

2018

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Identification of BMP9 and BMP10 as functional activators of the orphan activin receptor-like kinase 1 (ALK1) in endothelial cells

Blood, 2007-03, Vol.109 (5), p.1953-1961

2007

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Future treatments for hereditary hemorrhagic telangiectasia

Orphanet journal of rare diseases, 2020-01, Vol.15 (1), p.4-4, Article 4

2020

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Selective BMP-9 Inhibition Partially Protects Against Experimental Pulmonary Hypertension

Circulation research, 2019-03, Vol.124 (6), p.846-855

2019

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Bone Morphogenetic Protein 9 Is a Paracrine Factor Controlling Liver Sinusoidal Endothelial Cell Fenestration and Protecting Against Hepatic Fibrosis

Hepatology (Baltimore, Md.), 2019-10, Vol.70 (4), p.1392-1408

2019

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Restoring BMPRII functions in pulmonary arterial hypertension: opportunities, challenges and limitations

Expert opinion on therapeutic targets, 2017-02, Vol.21 (2), p.181-190

2017

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BMP9 and BMP10 are critical for postnatal retinal vascular remodeling

Blood, 2012-06, Vol.119 (25), p.6162-6171

2012

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Warning regarding hematological toxicity of tamoxifen activated CreERT2 in young Rosa26CreERT2 mice

Scientific reports, 2023-04, Vol.13 (1), p.5976-5976, Article 5976

2023

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Different cardiovascular and pulmonary phenotypes for single- and double-knock-out mice deficient in BMP9 and BMP10

Cardiovascular research, 2022-06, Vol.118 (7), p.1805-1820

2022

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Bone morphogenetic protein 9 (BMP9) controls lymphatic vessel maturation and valve formation

Blood, 2013-07, Vol.122 (4), p.598-607

2013

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Bone Morphogenetic Protein-9 Is a Circulating Vascular Quiescence Factor

Circulation research, 2008-04, Vol.102 (8), p.914-922

2008

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BMP9 is produced by hepatocytes and circulates mainly in an active mature form complexed to its prodomain

Cellular and molecular life sciences : CMLS, 2012-01, Vol.69 (2), p.313-324

2012

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TGF-β inhibitor therapy decreases fibrosis and stimulates cardiac improvement in a pre-clinical study of chronic Chagas' heart disease

PLoS neglected tropical diseases, 2019-07, Vol.13 (7), p.e0007602-e0007602

2019

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BMP9 and BMP10 are necessary for proper closure of the ductus arteriosus

Proceedings of the National Academy of Sciences - PNAS, 2015-06, Vol.112 (25), p.E3207-E3215

2015

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BMP9, but not BMP10, acts as a quiescence factor on tumor growth, vessel normalization and metastasis in a mouse model of breast cancer

Journal of experimental & clinical cancer research, 2018-08, Vol.37 (1), p.209-209, Article 209

2018

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Large-scale phosphoproteomics reveals activation of the MAPK/GADD45β/P38 axis and cell cycle inhibition in response to BMP9 and BMP10 stimulation in endothelial cells

Cell communication and signaling, 2024-03, Vol.22 (1), p.158-158, Article 158

2024

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Transforming growth factor-ß as a therapeutic target for the cardiac damage of Chagas disease

Memórias do Instituto Oswaldo Cruz, 2022, Vol.117, p.e210395-e210395

2022

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The Search for Biomarkers and Treatments in Chagas Disease: Insights From TGF-Beta Studies and Immunogenetics

Frontiers in cellular and infection microbiology, 2022-02, Vol.11, p.767576

2022

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Functional analysis of the BMP9 response of ALK1 mutants from HHT2 patients: a diagnostic tool for novel ACVRL1 mutations

Blood, 2010-09, Vol.116 (9), p.1604-1612

2010

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Differential Consequences of Bmp9 Deletion on Sinusoidal Endothelial Cell Differentiation and Liver Fibrosis in 129/Ola and C57BL/6 Mice

Cells (Basel, Switzerland), 2019-09, Vol.8 (9), p.1079

2019

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Bone Morphogenetic Protein 9 Regulates Early Lymphatic-Specified Endothelial Cell Expansion during Mouse Embryonic Stem Cell Differentiation

Stem cell reports, 2019-01, Vol.12 (1), p.98-111

2019

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Functional and splicing defect analysis of 23 ACVRL1 mutations in a cohort of patients affected by Hereditary Hemorrhagic Telangiectasia

PloS one, 2015-07, Vol.10 (7), p.e0132111-e0132111

2015

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Cruzipain Activates Latent TGF-β from Host Cells during T. cruzi Invasion

PloS one, 2015-05, Vol.10 (5), p.e0124832-e0124832

2015

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The quiescent endothelium: signalling pathways regulating organ-specific endothelial normalcy

Deciphering the complex role of thrombospondin-1 in glioblastoma development

Bone Morphogenetic Proteins in Vascular Homeostasis and Disease

Identification of BMP9 and BMP10 as functional activators of the orphan activin receptor-like kinase 1 (ALK1) in endothelial cells

Future treatments for hereditary hemorrhagic telangiectasia

Selective BMP-9 Inhibition Partially Protects Against Experimental Pulmonary Hypertension

Bone Morphogenetic Protein 9 Is a Paracrine Factor Controlling Liver Sinusoidal Endothelial Cell Fenestration and Protecting Against Hepatic Fibrosis

Restoring BMPRII functions in pulmonary arterial hypertension: opportunities, challenges and limitations

BMP9 and BMP10 are critical for postnatal retinal vascular remodeling

Warning regarding hematological toxicity of tamoxifen activated CreERT2 in young Rosa26CreERT2 mice

Different cardiovascular and pulmonary phenotypes for single- and double-knock-out mice deficient in BMP9 and BMP10

Bone morphogenetic protein 9 (BMP9) controls lymphatic vessel maturation and valve formation

Bone Morphogenetic Protein-9 Is a Circulating Vascular Quiescence Factor

BMP9 is produced by hepatocytes and circulates mainly in an active mature form complexed to its prodomain

TGF-β inhibitor therapy decreases fibrosis and stimulates cardiac improvement in a pre-clinical study of chronic Chagas' heart disease

BMP9 and BMP10 are necessary for proper closure of the ductus arteriosus

BMP9, but not BMP10, acts as a quiescence factor on tumor growth, vessel normalization and metastasis in a mouse model of breast cancer

Large-scale phosphoproteomics reveals activation of the MAPK/GADD45β/P38 axis and cell cycle inhibition in response to BMP9 and BMP10 stimulation in endothelial cells

Transforming growth factor-ß as a therapeutic target for the cardiac damage of Chagas disease

The Search for Biomarkers and Treatments in Chagas Disease: Insights From TGF-Beta Studies and Immunogenetics

Functional analysis of the BMP9 response of ALK1 mutants from HHT2 patients: a diagnostic tool for novel ACVRL1 mutations

Differential Consequences of Bmp9 Deletion on Sinusoidal Endothelial Cell Differentiation and Liver Fibrosis in 129/Ola and C57BL/6 Mice

Bone Morphogenetic Protein 9 Regulates Early Lymphatic-Specified Endothelial Cell Expansion during Mouse Embryonic Stem Cell Differentiation

Functional and splicing defect analysis of 23 ACVRL1 mutations in a cohort of patients affected by Hereditary Hemorrhagic Telangiectasia

Cruzipain Activates Latent TGF-β from Host Cells during T. cruzi Invasion

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