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Mitochondrial ROS in cancer: initiators, amplifiers or an Achilles' heel?

Nature reviews. Cancer, 2014-11, Vol.14 (11), p.709

2014

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Peroxiredoxin-5 targeted to the mitochondrial intermembrane space attenuates hypoxia-induced reactive oxygen species signalling

Biochemical journal, 2013-12, Vol.456 (3), p.337-346

2013

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Synthesis enables identification of the cellular target of leucascandrolide A and neopeltolide

Nature chemical biology, 2008-07, Vol.4 (7), p.418-424

2008

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H2O2 transit through the mitochondrial intermembrane space promotes tumor cell growth in vitro and in vivo

The Journal of biological chemistry, 2023-05, Vol.299 (5), p.104624-104624, Article 104624

2023

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GITR Agonism Enhances Cellular Metabolism to Support CD8 + T-cell Proliferation and Effector Cytokine Production in a Mouse Tumor Model

Cancer immunology research, 2018-10, Vol.6 (10), p.1199-1211

2018

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The Selective Protein Kinase C β Inhibitor Enzastaurin Induces Apoptosis in Cutaneous T-Cell Lymphoma Cell Lines through the AKT Pathway

Journal of investigative dermatology, 2006-07, Vol.126 (7), p.1641-1647

2006

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H 2 O 2 transit through the mitochondrial intermembrane space promotes tumor cell growth in vitro and in vivo

The Journal of biological chemistry, 2023-05, Vol.299 (5), p.104624

2023

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The Selective Protein Kinase C Inhibitor Enzastaurin Induces Apoptosis in Cutaneous T-Cell Lymphoma Cell Lines through the AKT Pathway

Journal of investigative dermatology, 2006-07, Vol.126 (7), p.1641-1647

2006

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Amaranthus crop for food security and sustainable food systems

Planta, 2024-09, Vol.260 (3), p.59, Article 59

2024

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Ransomware Attack: India Issues Red Alert

Emerging Technology in Modelling and Graphics, 2019, Vol.937, p.471-484

2019

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16 Tumor growth inhibition mediated by a single dose of intratumoral TransCon™ TLR7/8 agonist was associated with activated circulating T and B cells and sustained low levels of systemic cytokines

Journal for immunotherapy of cancer, 2021-11, Vol.9 (Suppl 2), p.A18-A18

2021

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769 A single dose of intratumoral TransCon™ TLR7/8 agonist monotherapy promoted sustained activation of antigen presenting cells resulting in CD4+ and CD8+ T cell activation and tumor growth inhibition

Journal for immunotherapy of cancer, 2021-11, Vol.9 (Suppl 2), p.A804-A804

2021

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TransCon IL-2 β/γ: a novel long-acting prodrug with sustained release of an IL-2Rβ/γ-selective IL-2 variant with improved pharmacokinetics and potent activation of cytotoxic immune cells for the treatment of cancer

Journal for immunotherapy of cancer, 2022-07, Vol.10 (7), p.e004991

2022

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Intratumoral delivery of TransCon™ TLR7/8 Agonist promotes sustained anti-tumor activity and local immune cell activation while minimizing systemic cytokine induction

Cancer cell international, 2022-09, Vol.22 (1), p.1-286, Article 286

2022

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Mitochondrial intermembrane space antioxidants attenuate hypoxia-induced reactive oxygen species signaling

Sabharwal, Simran Singh

2013

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Ransomware Attack : India issues Red Alert

International journal of engineering research & technology (Ahmedabad), 2018-02, Vol.7 (2)

2018

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Mitochondrial ROS in cancer: initiators, amplifiers or an Achilles' heel?

Peroxiredoxin-5 targeted to the mitochondrial intermembrane space attenuates hypoxia-induced reactive oxygen species signalling

Synthesis enables identification of the cellular target of leucascandrolide A and neopeltolide

H2O2 transit through the mitochondrial intermembrane space promotes tumor cell growth in vitro and in vivo

GITR Agonism Enhances Cellular Metabolism to Support CD8 + T-cell Proliferation and Effector Cytokine Production in a Mouse Tumor Model

The Selective Protein Kinase C β Inhibitor Enzastaurin Induces Apoptosis in Cutaneous T-Cell Lymphoma Cell Lines through the AKT Pathway

H 2 O 2 transit through the mitochondrial intermembrane space promotes tumor cell growth in vitro and in vivo

The Selective Protein Kinase C Inhibitor Enzastaurin Induces Apoptosis in Cutaneous T-Cell Lymphoma Cell Lines through the AKT Pathway

Amaranthus crop for food security and sustainable food systems

Ransomware Attack: India Issues Red Alert

16 Tumor growth inhibition mediated by a single dose of intratumoral TransCon™ TLR7/8 agonist was associated with activated circulating T and B cells and sustained low levels of systemic cytokines

769 A single dose of intratumoral TransCon™ TLR7/8 agonist monotherapy promoted sustained activation of antigen presenting cells resulting in CD4+ and CD8+ T cell activation and tumor growth inhibition

TransCon IL-2 β/γ: a novel long-acting prodrug with sustained release of an IL-2Rβ/γ-selective IL-2 variant with improved pharmacokinetics and potent activation of cytotoxic immune cells for the treatment of cancer

Intratumoral delivery of TransCon™ TLR7/8 Agonist promotes sustained anti-tumor activity and local immune cell activation while minimizing systemic cytokine induction

Mitochondrial intermembrane space antioxidants attenuate hypoxia-induced reactive oxygen species signaling

Ransomware Attack : India issues Red Alert

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