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The emerging role of peptidyl‐prolyl isomerase chaperones in tau oligomerization, amyloid processing, and Alzheimer's disease

Journal of neurochemistry, 2015-04, Vol.133 (1), p.1-13

2015

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Hsp90 activator Aha1 drives production of pathological tau aggregates

Proceedings of the National Academy of Sciences - PNAS, 2017-09, Vol.114 (36), p.9707-9712

2017

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Age-associated epigenetic upregulation of the FKBP5 gene selectively impairs stress resiliency

PloS one, 2014-09, Vol.9 (9), p.e107241-e107241

2014

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Human cyclophilin 40 unravels neurotoxic amyloids

PLoS biology, 2017-06, Vol.15 (6), p.e2001336

2017

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Cellular factors modulating the mechanism of tau protein aggregation

Cellular and Molecular Life Sciences, 2015-05, Vol.72 (10), p.1863-1879

2015

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The Metamorphic Nature of the Tau Protein: Dynamic Flexibility Comes at a Cost

Frontiers in neuroscience, 2016-01, Vol.10, p.3-3

2016

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Alzheimer's disease biomarkers: Correspondence between human studies and animal models

Neurobiology of disease, 2013-08, Vol.56, p.116-130

2013

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Hippocampal Neurogenesis Is Enhanced in Adult Tau Deficient Mice

Cells (Basel, Switzerland), 2020-01, Vol.9 (1), p.210

2020

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Chronic ketamine produces altered distribution of parvalbumin-positive cells in the hippocampus of adult rats

Neuroscience letters, 2013-08, Vol.550, p.69-74

2013

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DnaJ/Hsc70 chaperone complexes control the extracellular release of neurodegenerative-associated proteins

The EMBO journal, 2016-07, Vol.35 (14), p.1537-1549

2016

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Targeting Hsp90 and its co-chaperones to treat Alzheimer's disease

Expert opinion on therapeutic targets, 2014-10, Vol.18 (10), p.1219-1232

2014

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MicroRNA-511 Binds to FKBP5 mRNA, Which Encodes a Chaperone Protein, and Regulates Neuronal Differentiation

The Journal of biological chemistry, 2016-08, Vol.291 (34), p.17897-17906

2016

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Animal systems in the development of treatments for Alzheimer's disease: challenges, methods, and implications

Neurobiology of aging, 2013, Vol.34 (1), p.169-183

2013

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Targeting the ER-autophagy system in the trabecular meshwork to treat glaucoma

Experimental eye research, 2016-03, Vol.144, p.38-45

2016

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Tau depletion prevents progressive blood-brain barrier damage in a mouse model of tauopathy

Acta neuropathologica communications, 2015-01, Vol.3 (1), p.8-8, Article 8

2015

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Targeting the FKBP51/GR/Hsp90 Complex to Identify Functionally Relevant Treatments for Depression and PTSD

ACS chemical biology, 2018-08, Vol.13 (8), p.2288-2299

2018

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Torpor Does Not Influence Spatial Memory in Hibernating Golden-Mantled Ground Squirrels ( Spermophilus [Callospermophilus] lateralis )

Physiological and biochemical zoology, 2022-09, Vol.95 (5), p.390-399

2022

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Isoform-selective Genetic Inhibition of Constitutive Cytosolic Hsp70 Activity Promotes Client Tau Degradation Using an Altered Co-chaperone Complement

The Journal of biological chemistry, 2015-05, Vol.290 (21), p.13115-13127

2015

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The active Hsc70/tau complex can be exploited to enhance tau turnover without damaging microtubule dynamics

Human molecular genetics, 2015-07, Vol.24 (14), p.3971-3981

2015

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Effect of acute lipopolysaccharide-induced inflammation in intracerebroventricular-streptozotocin injected rats

Neuropharmacology, 2016-02, Vol.101, p.110-122

2016

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Deficits in emotional learning and memory in an animal model of schizophrenia

Behavioural brain research, 2012-07, Vol.233 (1), p.35-44

2012

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Inhibition of Both Hsp70 Activity and Tau Aggregation in Vitro Best Predicts Tau Lowering Activity of Small Molecules

ACS chemical biology, 2016-07, Vol.11 (7), p.2041-2048

2016

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Noncontact Rotational Head Injury Produces Transient Cognitive Deficits but Lasting Neuropathological Changes

Journal of neurotrauma, 2016-10, Vol.33 (19), p.1751-1760

2016

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Postnatal alterations in GABAB receptor tone produce sensorimotor gating deficits and protein level differences in adulthood

International journal of developmental neuroscience, 2015-04, Vol.41 (1), p.17-27

2015

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Examination of ketamine-induced deficits in sensorimotor gating and spatial learning

Physiology & behavior, 2012-10, Vol.107 (3), p.355-363

2012

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The emerging role of peptidyl‐prolyl isomerase chaperones in tau oligomerization, amyloid processing, and Alzheimer's disease

Hsp90 activator Aha1 drives production of pathological tau aggregates

Age-associated epigenetic upregulation of the FKBP5 gene selectively impairs stress resiliency

Human cyclophilin 40 unravels neurotoxic amyloids

Cellular factors modulating the mechanism of tau protein aggregation

The Metamorphic Nature of the Tau Protein: Dynamic Flexibility Comes at a Cost

Alzheimer's disease biomarkers: Correspondence between human studies and animal models

Hippocampal Neurogenesis Is Enhanced in Adult Tau Deficient Mice

Chronic ketamine produces altered distribution of parvalbumin-positive cells in the hippocampus of adult rats

DnaJ/Hsc70 chaperone complexes control the extracellular release of neurodegenerative-associated proteins

Targeting Hsp90 and its co-chaperones to treat Alzheimer's disease

MicroRNA-511 Binds to FKBP5 mRNA, Which Encodes a Chaperone Protein, and Regulates Neuronal Differentiation

Animal systems in the development of treatments for Alzheimer's disease: challenges, methods, and implications

Targeting the ER-autophagy system in the trabecular meshwork to treat glaucoma

Tau depletion prevents progressive blood-brain barrier damage in a mouse model of tauopathy

Targeting the FKBP51/GR/Hsp90 Complex to Identify Functionally Relevant Treatments for Depression and PTSD

Torpor Does Not Influence Spatial Memory in Hibernating Golden-Mantled Ground Squirrels ( Spermophilus [Callospermophilus] lateralis )

Isoform-selective Genetic Inhibition of Constitutive Cytosolic Hsp70 Activity Promotes Client Tau Degradation Using an Altered Co-chaperone Complement

The active Hsc70/tau complex can be exploited to enhance tau turnover without damaging microtubule dynamics

Effect of acute lipopolysaccharide-induced inflammation in intracerebroventricular-streptozotocin injected rats

Deficits in emotional learning and memory in an animal model of schizophrenia

Inhibition of Both Hsp70 Activity and Tau Aggregation in Vitro Best Predicts Tau Lowering Activity of Small Molecules

Noncontact Rotational Head Injury Produces Transient Cognitive Deficits but Lasting Neuropathological Changes

Postnatal alterations in GABAB receptor tone produce sensorimotor gating deficits and protein level differences in adulthood

Examination of ketamine-induced deficits in sensorimotor gating and spatial learning

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