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WAY-163909 [(7bR,10aR)-1,2,3,4,8,9,10,10a-octahydro-7bH-cyclopenta-[b][1,4]diazepino[6,7,1hi]indole]: A novel 5-hydroxytryptamine 2C receptor-selective agonist with preclinical antipsychotic-like activity

The Journal of pharmacology and experimental therapeutics, 2007-01, Vol.320 (1), p.486-496

2007

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WAY-163909 [(7bR, 10aR)-1,2,3,4,8,9,10,10a-octahydro-7bH-cyclopenta-[b][1,4]diazepino[6,7,1hi]indole], a novel 5-hydroxytryptamine 2C receptor-selective agonist with anorectic activity

The Journal of pharmacology and experimental therapeutics, 2005-05, Vol.313 (2), p.862-869

2005

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First Scale-Up: Problems and Resolutions on the Synthesis of WAY-253752, a Novel, Dual-Acting SSRI/5HT1A Antagonist

Organic process research & development, 2008-01, Vol.12 (1), p.76-80

2008

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Cycloalkyl[b][1,4]benzodiazepinoindoles are agonists at the human 5-HT2C receptor

Bioorganic & medicinal chemistry letters, 2004-05, Vol.14 (10), p.2603-2607

2004

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The preclinical pharmacological profile of WAY-132983, a potent M1 preferring agonist

The Journal of pharmacology and experimental therapeutics, 2000-02, Vol.292 (2), p.584

2000

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1,2,5-Thiadiazole derivatives are potent and selective ligands at human 5-HT1A receptors

Bioorganic & medicinal chemistry letters, 2001-04, Vol.11 (8), p.1069-1071

2001

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Cycloalkyl[ b][1,4]benzodiazepinoindoles are agonists at the human 5-HT 2C receptor

Bioorganic & medicinal chemistry letters, 2004-05, Vol.14 (10), p.2603-2607

2004

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First Scale-Up: Problems and Resolutions on the Synthesis of WAY-253752, a Novel, Dual-Acting SSRI/5HT 1A Antagonist

Organic process research & development, 2008-01, Vol.12 (1), p.76-80

2008

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Studies on the molybdenum cofactor: model synthetic routes directed at Form B

Journal of organic chemistry, 1988-12, Vol.53 (25), p.5839-5847

1988

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Synthesis and 5-hydroxytryptamine (5-HT) activity of 2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5-(6H)ones and 2,3,4,4a, 5,6-hexahydro-1H-pyrazino[1,2-a]quinoxalines

Bioorganic & medicinal chemistry letters, 2000-09, Vol.10 (17), p.1991-1994

2000

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1,2,5-Thiadiazole derivatives are potent and selective ligands at human 5-HT 1A receptors

Bioorganic & medicinal chemistry letters, 2001, Vol.11 (8), p.1069-1071

2001

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Discovery of a highly potent, functionally-selective muscarinic M1 agonist, way-132983 using rational drug design and receptor modelling

Bioorganic & medicinal chemistry letters, 1999-07, Vol.9 (14), p.1895-1900

1999

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Discovery of a highly potent, functionally-selective muscarinic M 1 agonist,WAY-132983 using rational drug design and receptor modelling

Bioorganic & medicinal chemistry letters, 1999-07, Vol.9 (14), p.1895-1900

1999

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Synthesis and 5-Hydroxytryptamine (5-HT) activity of 2,3,4,4a-Tetrahydro-1 H-pyrazino[1,2- a]quinoxalin-5-(6 H)ones and 2,3,4,4a,5,6-Hexahydro-1 H-pyrazino[1,2- a]quinoxalines

Bioorganic & medicinal chemistry letters, 2000, Vol.10 (17), p.1991-1994

2000

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WAY-131256 is an orally active, efficacious, and in vivo functionally selective M1 agonist

Drug development research, 1997-02, Vol.40 (2), p.185-192

1997

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A Convenient Synthesis of t-butyl p-Aminobenzoate

Synthetic communications, 1984-08, Vol.14 (10), p.921-924

1984

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Cycloalkyl[b][1,4]benzodiazepinoindoles Are Agonists at the Human 5‐HT 2C Receptor

ChemInform, 2004-09, Vol.35 (38)

2004

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Cycloalkyl[b][1,4]benzodiazepinoindoles Are Agonists at the Human 5-HT2C Receptor

ChemInform, 2004-09, Vol.35 (38), p.no-no

2004

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ChemInform Abstract: 1,2,5-Thiadiazole Derivatives Are Potent and Selective Ligands at Human 5-HT1A Receptors

ChemInform, 2001-08, Vol.32 (33), p.no-no

2001

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ChemInform Abstract: 1,2,5‐Thiadiazole Derivatives Are Potent and Selective Ligands at Human 5‐HT 1A Receptors

ChemInform, 2001-08, Vol.32 (33)

2001

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ChemInform Abstract: Discovery of a Highly Potent, Functionally‐Selective Muscarinic M 1 Agonist, WAY‐132983 Using Rational Drug Design and Receptor Modeling

ChemInform, 1999-10, Vol.30 (43)

1999

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ChemInform Abstract: Discovery of a Highly Potent, Functionally-Selective Muscarinic M1 Agonist, WAY-132983 Using Rational Drug Design and Receptor Modeling

ChemInform, 1999-10, Vol.30 (43), p.no-no

1999

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Antidepressant-like effects of the novel, selective, 5-HT2C receptor agonist WAY-163909 in rodents

Psychopharmacologia, 2007-06, Vol.192 (2), p.159-170

2007

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WAY-163909 [(7bR,10aR)-1,2,3,4,8,9,10,10a-octahydro-7bH-cyclopenta-[b][1,4]diazepino[6,7,1hi]indole]: A novel 5-hydroxytryptamine 2C receptor-selective agonist with preclinical antipsychotic-like activity

WAY-163909 [(7bR, 10aR)-1,2,3,4,8,9,10,10a-octahydro-7bH-cyclopenta-[b][1,4]diazepino[6,7,1hi]indole], a novel 5-hydroxytryptamine 2C receptor-selective agonist with anorectic activity

The Synthesis and Biological Evaluation of Quinolyl-piperazinyl Piperidines as Potent Serotonin 5-HT1A Antagonists

First Scale-Up: Problems and Resolutions on the Synthesis of WAY-253752, a Novel, Dual-Acting SSRI/5HT1A Antagonist

Cycloalkyl[b][1,4]benzodiazepinoindoles are agonists at the human 5-HT2C receptor

The preclinical pharmacological profile of WAY-132983, a potent M1 preferring agonist

1,2,5-Thiadiazole derivatives are potent and selective ligands at human 5-HT1A receptors

Cycloalkyl[ b][1,4]benzodiazepinoindoles are agonists at the human 5-HT 2C receptor

The Synthesis and Biological Evaluation of Quinolyl-piperazinyl Piperidines as Potent Serotonin 5-HT 1A Antagonists

First Scale-Up: Problems and Resolutions on the Synthesis of WAY-253752, a Novel, Dual-Acting SSRI/5HT 1A Antagonist

Studies on the molybdenum cofactor: model synthetic routes directed at Form B

Synthesis and 5-hydroxytryptamine (5-HT) activity of 2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5-(6H)ones and 2,3,4,4a, 5,6-hexahydro-1H-pyrazino[1,2-a]quinoxalines

1,2,5-Thiadiazole derivatives are potent and selective ligands at human 5-HT 1A receptors

Discovery of a highly potent, functionally-selective muscarinic M1 agonist, way-132983 using rational drug design and receptor modelling

Discovery of a highly potent, functionally-selective muscarinic M 1 agonist,WAY-132983 using rational drug design and receptor modelling

Synthesis and 5-Hydroxytryptamine (5-HT) activity of 2,3,4,4a-Tetrahydro-1 H-pyrazino[1,2- a]quinoxalin-5-(6 H)ones and 2,3,4,4a,5,6-Hexahydro-1 H-pyrazino[1,2- a]quinoxalines

WAY-131256 is an orally active, efficacious, and in vivo functionally selective M1 agonist

A Convenient Synthesis of t-butyl p-Aminobenzoate

Cycloalkyl[b][1,4]benzodiazepinoindoles Are Agonists at the Human 5‐HT 2C Receptor

Cycloalkyl[b][1,4]benzodiazepinoindoles Are Agonists at the Human 5-HT2C Receptor

ChemInform Abstract: 1,2,5-Thiadiazole Derivatives Are Potent and Selective Ligands at Human 5-HT1A Receptors

ChemInform Abstract: 1,2,5‐Thiadiazole Derivatives Are Potent and Selective Ligands at Human 5‐HT 1A Receptors

ChemInform Abstract: Discovery of a Highly Potent, Functionally‐Selective Muscarinic M 1 Agonist, WAY‐132983 Using Rational Drug Design and Receptor Modeling

ChemInform Abstract: Discovery of a Highly Potent, Functionally-Selective Muscarinic M1 Agonist, WAY-132983 Using Rational Drug Design and Receptor Modeling

Antidepressant-like effects of the novel, selective, 5-HT2C receptor agonist WAY-163909 in rodents

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