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Ketamine: A Review of Clinical Pharmacokinetics and Pharmacodynamics in Anesthesia and Pain Therapy

Clinical pharmacokinetics, 2016-09, Vol.55 (9), p.1059-1077

2016

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A Physiologically Based Pharmacokinetic Model of Voriconazole Integrating Time-Dependent Inhibition of CYP3A4, Genetic Polymorphisms of CYP2C19 and Predictions of Drug–Drug Interactions

Clinical pharmacokinetics, 2020-06, Vol.59 (6), p.781-808

2020

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S-ketamine in patient-controlled analgesia reduces opioid consumption in a dose-dependent manner after major lumbar fusion surgery: A randomized, double-blind, placebo-controlled clinical trial

PloS one, 2021-06, Vol.16 (6), p.e0252626-e0252626

2021

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Enhancement of GABAergic activity: neuropharmacological effects of benzodiazepines and therapeutic use in anesthesiology

Pharmacological reviews, 2011-03, Vol.63 (1), p.243-267

2011

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Does the pharmacology of oxycodone justify its increasing use as an analgesic?

Trends in pharmacological sciences (Regular ed.), 2013-04, Vol.34 (4), p.206-214

2013

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Clinical Pharmacokinetics and Pharmacodynamics of Naloxone

Clinical pharmacokinetics, 2024-04, Vol.63 (4), p.397-422

2024

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Rifampin Greatly Reduces the Plasma Concentrations of Intravenous and Oral Oxycodone

Anesthesiology (Philadelphia), 2009-06, Vol.110 (6), p.1371-1378

2009

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Voriconazole greatly increases the exposure to oral buprenorphine

European journal of clinical pharmacology, 2018-12, Vol.74 (12), p.1615-1622

2018

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A Semiphysiological Population Pharmacokinetic Model for Dynamic Inhibition of Liver and Gut Wall Cytochrome P450 3A by Voriconazole

Clinical pharmacokinetics, 2013-09, Vol.52 (9), p.763-781

2013

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Effects of terbinafine and itraconazole on the pharmacokinetics of orally administered tramadol

European journal of clinical pharmacology, 2015-03, Vol.71 (3), p.321-327

2015

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Voriconazole more likely than posaconazole increases plasma exposure to sublingual buprenorphine causing a risk of a clinically important interaction

European journal of clinical pharmacology, 2016-11, Vol.72 (11), p.1363-1371

2016

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Premedication with intranasal dexmedetomidine decreases barbiturate requirement in pediatric patients sedated for magnetic resonance imaging: a retrospective study

BMC anesthesiology, 2019-02, Vol.19 (1), p.22-22, Article 22

2019

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Pharmacokinetics and Sedative Effects of Intranasal Dexmedetomidine in Ambulatory Pediatric Patients

Anesthesia and analgesia, 2020-04, Vol.130 (4), p.949-957

2020

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Determination of total and unbound sufentanil in human plasma by ultrafiltration and LC–MS/MS: Application to clinical pharmacokinetic study

Journal of pharmaceutical and biomedical analysis, 2012-07, Vol.66, p.306-313

2012

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Effects of itraconazole on the pharmacokinetics and pharmacodynamics of intravenously and orally administered oxycodone

European journal of clinical pharmacology, 2010-04, Vol.66 (4), p.387-397

2010

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Miconazole Oral Gel Increases Exposure to Oral Oxycodone by Inhibition of CYP2D6 and CYP3A4

Antimicrobial Agents and Chemotherapy, 2011-03, Vol.55 (3), p.1063-1067

2011

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Population Modelling of Dexmedetomidine Pharmacokinetics and Haemodynamic Effects After Intravenous and Subcutaneous Administration

Clinical pharmacokinetics, 2020-11, Vol.59 (11), p.1467-1482

2020

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Intranasal Low-Dose Dexmedetomidine Reduces Postoperative Opioid Requirement in Patients Undergoing Hip Arthroplasty Under General Anesthesia

The Journal of arthroplasty, 2019-04, Vol.34 (4), p.686-692.e2

2019

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Intranasal Dexmedetomidine Reduces Postoperative Opioid Requirement in Patients Undergoing Total Knee Arthroplasty Under General Anesthesia

The Journal of arthroplasty, 2021-03, Vol.36 (3), p.978-985.e1

2021

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Absorption pharmacokinetics and feasibility of intranasal dexmedetomidine in patients under general anaesthesia

Acta anaesthesiologica Scandinavica, 2024-06, Vol.68 (9), p.1182-1191

2024

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Rifampicin decreases exposure to sublingual buprenorphine in healthy subjects

Pharmacology research & perspectives, 2016-12, Vol.4 (6), p.e00271-n/a

2016

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Ketamine Pharmacokinetics: A Systematic Review of the Literature, Meta-analysis, and Population Analysis

Anesthesiology (Philadelphia), 2020-12, Vol.133 (6), p.1192-1213

2020

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Cerebral autoregulation after aneurysmal subarachnoid haemorrhage. A preliminary study comparing dexmedetomidine to propofol and/or midazolam

Acta anaesthesiologica Scandinavica, 2020-10, Vol.64 (9), p.1278-1286

2020

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Relationship of Edoxaban Plasma Concentration and Blood Coagulation in Healthy Volunteers Using Standard Laboratory Tests and Viscoelastic Analysis

Journal of clinical pharmacology, 2021-04, Vol.61 (4), p.522-530

2021

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Ketamine: A Review of Clinical Pharmacokinetics and Pharmacodynamics in Anesthesia and Pain Therapy

A Physiologically Based Pharmacokinetic Model of Voriconazole Integrating Time-Dependent Inhibition of CYP3A4, Genetic Polymorphisms of CYP2C19 and Predictions of Drug–Drug Interactions

S-ketamine in patient-controlled analgesia reduces opioid consumption in a dose-dependent manner after major lumbar fusion surgery: A randomized, double-blind, placebo-controlled clinical trial

Enhancement of GABAergic activity: neuropharmacological effects of benzodiazepines and therapeutic use in anesthesiology

Effect of xenon on brain injury, neurological outcome, and survival in patients after aneurysmal subarachnoid hemorrhage-study protocol for a randomized clinical trial

Does the pharmacology of oxycodone justify its increasing use as an analgesic?

Clinical Pharmacokinetics and Pharmacodynamics of Naloxone

Rifampin Greatly Reduces the Plasma Concentrations of Intravenous and Oral Oxycodone

Voriconazole greatly increases the exposure to oral buprenorphine

A Semiphysiological Population Pharmacokinetic Model for Dynamic Inhibition of Liver and Gut Wall Cytochrome P450 3A by Voriconazole

Effects of terbinafine and itraconazole on the pharmacokinetics of orally administered tramadol

Voriconazole more likely than posaconazole increases plasma exposure to sublingual buprenorphine causing a risk of a clinically important interaction

Premedication with intranasal dexmedetomidine decreases barbiturate requirement in pediatric patients sedated for magnetic resonance imaging: a retrospective study

Pharmacokinetics and Sedative Effects of Intranasal Dexmedetomidine in Ambulatory Pediatric Patients

Determination of total and unbound sufentanil in human plasma by ultrafiltration and LC–MS/MS: Application to clinical pharmacokinetic study

Effects of itraconazole on the pharmacokinetics and pharmacodynamics of intravenously and orally administered oxycodone

Miconazole Oral Gel Increases Exposure to Oral Oxycodone by Inhibition of CYP2D6 and CYP3A4

Population Modelling of Dexmedetomidine Pharmacokinetics and Haemodynamic Effects After Intravenous and Subcutaneous Administration

Intranasal Low-Dose Dexmedetomidine Reduces Postoperative Opioid Requirement in Patients Undergoing Hip Arthroplasty Under General Anesthesia

Intranasal Dexmedetomidine Reduces Postoperative Opioid Requirement in Patients Undergoing Total Knee Arthroplasty Under General Anesthesia

Absorption pharmacokinetics and feasibility of intranasal dexmedetomidine in patients under general anaesthesia

Rifampicin decreases exposure to sublingual buprenorphine in healthy subjects

Ketamine Pharmacokinetics: A Systematic Review of the Literature, Meta-analysis, and Population Analysis

Cerebral autoregulation after aneurysmal subarachnoid haemorrhage. A preliminary study comparing dexmedetomidine to propofol and/or midazolam

Relationship of Edoxaban Plasma Concentration and Blood Coagulation in Healthy Volunteers Using Standard Laboratory Tests and Viscoelastic Analysis

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