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Selective Intracellular Activation of a Novel Prodrug of the Human Immunodeficiency Virus Reverse Transcriptase Inhibitor Tenofovir Leads to Preferential Distribution and Accumulation in Lymphatic Tissue

Antimicrobial Agents and Chemotherapy, 2005-05, Vol.49 (5), p.1898-1906

2005

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Cathepsin A Is the Major Hydrolase Catalyzing the Intracellular Hydrolysis of the Antiretroviral Nucleotide Phosphonoamidate Prodrugs GS-7340 and GS-9131

Antimicrobial Agents and Chemotherapy, 2007-02, Vol.51 (2), p.543-550

2007

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Discovery and development of oseltamivir at Gilead Sciences

Antiviral Therapy, 2022-04, Vol.27 (2), p.13596535211067598-13596535211067598

2022

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Small Molecules VP-14637 and JNJ-2408068 Inhibit Respiratory Syncytial Virus Fusion by Similar Mechanisms

Antimicrobial Agents and Chemotherapy, 2005-06, Vol.49 (6), p.2460-2466

2005

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In Vitro Characterization of GS-8374, a Novel Phosphonate-Containing Inhibitor of HIV-1 Protease with a Favorable Resistance Profile

Antimicrobial Agents and Chemotherapy, 2011-04, Vol.55 (4), p.1366-1376

2011

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Inhibition of Respiratory Syncytial Virus Fusion by the Small Molecule VP-14637 via Specific Interactions with F Protein

Journal of Virology, 2003-05, Vol.77 (9), p.5054-5064

2003

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Suppression of HIV-1 Protease Inhibitor Resistance by Phosphonate-mediated Solvent Anchoring

Journal of molecular biology, 2006-10, Vol.363 (3), p.635-647

2006

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Disability Design and Innovation in Low Resource Settings: Addressing Inequality Through HCI

Extended Abstracts of the 2021 CHI Conference on Human Factors in Computing Systems, 2021, p.1-5

2021

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Discovery of β-d-2′-deoxy-2′-α-fluoro-4′-α-cyano-5-aza-7,9-dideaza adenosine as a potent nucleoside inhibitor of respiratory syncytial virus with excellent selectivity over mitochondrial RNA and DNA polymerases

Bioorganic & medicinal chemistry letters, 2015-06, Vol.25 (12), p.2484-2487

2015

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Delivery of digital video and other multimedia services (>1 Gb/s bandwidth) in passband above the 155 Mb/s baseband services on a FTTx full service access network

Journal of lightwave technology, 1999-12, Vol.17 (12), p.2449-2460

1999

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IEEE_Xplore

Structure–activity relationships of diamine inhibitors of cytochrome P450 (CYP) 3A as novel pharmacoenhancers. Part II: P2/P3 region and discovery of cobicistat (GS-9350)

Bioorganic & medicinal chemistry letters, 2014-02, Vol.24 (3), p.995-999

2014

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Privacy Considerations of the Visually Impaired with Camera Based Assistive Technologies: Misrepresentation, Impropriety, and Fairness

Proceedings of the 22nd International ACM SIGACCESS Conference on Computers and Accessibility, 2020, p.1-14

2020

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Synthesis, anti-HIV activity, and resistance profile of thymidine phosphonomethoxy nucleosides and their bis-isopropyloxymethylcarbonyl (bisPOC) prodrugs

Bioorganic & medicinal chemistry, 2007-08, Vol.15 (16), p.5519-5528

2007

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Synthesis And Anti-Hiv Activity Of Cyclic Pyrimidine Phosphonomethoxy Nucleosides And Their Prodrugs: A Comparison Of Phosphonates And Corresponding Nucleosides

Nucleosides, nucleotides & nucleic acids, 2007-01, Vol.26 (6-7), p.573-577

2007

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LB-2Nucleotide Prodrug GS-5734 Is a Broad-Spectrum Filovirus Inhibitor That Provides Complete Therapeutic Protection Against the Development of Ebola Virus Disease (EVD) in Infected Non-human Primates

Open forum infectious diseases, 2015-12, Vol.2 (suppl_1), p.S67-S67

2015

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Erythrocyte creatine levels in hyperthyroidism

Pathology, 1994, Vol.26 (3), p.291-293

1994

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Erythrocyte Sodium-Lithium Countertransport Activity has no Predictive Value for Pregnancy-Induced Hypertension

Hypertension in pregnancy, 1994, Vol.13 (1), p.43-50

1994

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Effect of cyproheptadine and atropine on the diurnal prolactin responses to insulin-induced hypoglycemia in normal men

The journal of clinical endocrinology and metabolism, 1980-07, Vol.51 (1), p.90-92

1980

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Selective Intracellular Activation of a Novel Prodrug of the Human Immunodeficiency Virus Reverse Transcriptase Inhibitor Tenofovir Leads to Preferential Distribution and Accumulation in Lymphatic Tissue

Cathepsin A Is the Major Hydrolase Catalyzing the Intracellular Hydrolysis of the Antiretroviral Nucleotide Phosphonoamidate Prodrugs GS-7340 and GS-9131

Discovery and development of oseltamivir at Gilead Sciences

Small Molecules VP-14637 and JNJ-2408068 Inhibit Respiratory Syncytial Virus Fusion by Similar Mechanisms

In Vitro Characterization of GS-8374, a Novel Phosphonate-Containing Inhibitor of HIV-1 Protease with a Favorable Resistance Profile

Inhibition of Respiratory Syncytial Virus Fusion by the Small Molecule VP-14637 via Specific Interactions with F Protein

Suppression of HIV-1 Protease Inhibitor Resistance by Phosphonate-mediated Solvent Anchoring

Discovery and Synthesis of a Phosphoramidate Prodrug of a Pyrrolo[2,1‑f][triazin-4-amino] Adenine C‑Nucleoside (GS-5734) for the Treatment of Ebola and Emerging Viruses

Disability Design and Innovation in Low Resource Settings: Addressing Inequality Through HCI

Discovery of β-d-2′-deoxy-2′-α-fluoro-4′-α-cyano-5-aza-7,9-dideaza adenosine as a potent nucleoside inhibitor of respiratory syncytial virus with excellent selectivity over mitochondrial RNA and DNA polymerases

Delivery of digital video and other multimedia services (>1 Gb/s bandwidth) in passband above the 155 Mb/s baseband services on a FTTx full service access network

Structure–activity relationships of diamine inhibitors of cytochrome P450 (CYP) 3A as novel pharmacoenhancers. Part II: P2/P3 region and discovery of cobicistat (GS-9350)

Privacy Considerations of the Visually Impaired with Camera Based Assistive Technologies: Misrepresentation, Impropriety, and Fairness

Synthesis, anti-HIV activity, and resistance profile of thymidine phosphonomethoxy nucleosides and their bis-isopropyloxymethylcarbonyl (bisPOC) prodrugs

Nucleotide Prodrug GS-5734 Is a Broad-Spectrum Filovirus Inhibitor That Provides Complete Therapeutic Protection Against the Development of Ebola Virus Disease (EVD) in Infected Non-human Primates

Discovery of GS-8374, a potent human immunodeficiency virus type 1 protease inhibitor with a superior resistance profile

Synthesis And Anti-Hiv Activity Of Cyclic Pyrimidine Phosphonomethoxy Nucleosides And Their Prodrugs: A Comparison Of Phosphonates And Corresponding Nucleosides

LB-2Nucleotide Prodrug GS-5734 Is a Broad-Spectrum Filovirus Inhibitor That Provides Complete Therapeutic Protection Against the Development of Ebola Virus Disease (EVD) in Infected Non-human Primates

Erythrocyte creatine levels in hyperthyroidism

Erythrocyte Sodium-Lithium Countertransport Activity has no Predictive Value for Pregnancy-Induced Hypertension

Effect of cyproheptadine and atropine on the diurnal prolactin responses to insulin-induced hypoglycemia in normal men

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