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Relationships between pazopanib exposure and clinical safety and efficacy in patients with advanced renal cell carcinoma

British journal of cancer, 2014-11, Vol.111 (10), p.1909-1916

2014

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A Phase I Study of the Pharmacokinetic and Safety Profiles of Oral Pazopanib With a High-Fat or Low-Fat Meal in Patients With Advanced Solid Tumors

Clinical pharmacology and therapeutics, 2010-12, Vol.88 (6), p.818-823

2010

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Phase I study of weekly paclitaxel in combination with pazopanib and lapatinib in advanced solid malignancies

British journal of cancer, 2014-05, Vol.110 (11), p.2647-2654

2014

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Pazopanib exposure decreases as a result of an ifosfamide-dependent drug–drug interaction: results of a phase I study

British journal of cancer, 2014-02, Vol.110 (4), p.888-893

2014

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Preclinical Modeling of Tumor Growth and Angiogenesis Inhibition to Describe Pazopanib Clinical Effects in Renal Cell Carcinoma

CPT: pharmacometrics and systems pharmacology, 2015-11, Vol.4 (11), p.660-668

2015

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An Evaluation of the Drug Interaction Potential of Pazopanib, an Oral Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Inhibitor, Using a Modified Cooperstown 5+1 Cocktail in Patients With Advanced Solid Tumors

Clinical pharmacology and therapeutics, 2010-11, Vol.88 (5), p.652-659

2010

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Relationships between pazopanib exposure and clinical safety and efficacy in patients with advanced renal cell carcinoma

British journal of cancer, 2014-12, Vol.111 (12), p.2383-2383

2014

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Bile flow but not enterohepatic recirculation influences the pharmacokinetics of ranitidine in the rat

Drug metabolism and disposition, 1994-03, Vol.22 (2), p.224

1994

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Comparison of zafirlukast (Accolate®) absorption after oral and colonic administration in humans

Pharmaceutical research, 2000-02, Vol.17 (2), p.154-159

2000

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Regional gastrointestinal absorption of ranitidine in the rat

Pharmaceutical research, 1995-09, Vol.12 (9), p.1311-1315

1995

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Gastrointestinal transit and distribution of ranitidine in the rat

Pharmaceutical research, 1995-09, Vol.12 (9), p.1316-1322

1995

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Use of a pharmacokinetic model incorporating discontinuous gastrointestinal absorption to examine the occurrence of double peaks in oral concentration-time profiles

Pharmaceutical research, 1992-03, Vol.9 (3), p.350-356

1992

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Erratum: Relationships between pazopanib exposure and clinical safety and efficacy in patients with advanced renal cell carcinoma

British journal of cancer, 2014-12, Vol.111 (12), p.2383-2383

2014

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Changes in polyvinylpyrrolidone coil dimensions by complexation with organic anions : effect of chain length

Colloid and polymer science, 1991-07, Vol.269 (7), p.643-649

1991

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Pazopanib and lapatinib in patients with relapsed malignant glioma: Results of a phase I/II study

Journal of clinical oncology, 2009-05, Vol.27 (15_suppl), p.2040-2040

2009

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A phase I study of pazopanib in patients with advanced hepatocellular carcinoma

Journal of clinical oncology, 2009-05, Vol.27 (15_suppl), p.3561-3561

2009

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An Evaluation of the Drug Interaction Potential of Pazopanib, an Oral Vascular Endothelial Growth Factor ReceptorTyrosine Kinase Inhibitor, Using a Modified Cooperstown 5+1 Cocktail in Patients With Advanced Solid Tumors

Clinical pharmacology and therapeutics, 2010, Vol.88 (5), p.652-659

2010

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A phase I, open-label study of the safety and pharmacokinetics (PK) of pazopanib (P) and lapatinib (L) administered concurrently

Journal of clinical oncology, 2006-06, Vol.24 (18_suppl), p.3088-3088

2006

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Pharmacokinetics (PK) and tolerability of GW786034, a VEGFR tyrosine kinase inhibitor, after daily oral administration to patients with solid tumors

Journal of clinical oncology, 2004-07, Vol.22 (14_suppl), p.3054-3054

2004

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Pharmacokinetics (PK) and tolerability of GW786034, a VEGFR tyrosine kinase inhibitor, after daily oral administration to patients with solid tumors

Journal of clinical oncology, 2004-07, Vol.22 (14_suppl), p.3054-3054

2004

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The absolute bioavailability of oral vinorelbine in patients with solid tumors

Cancer chemotherapy and pharmacology, 2005-12, Vol.56 (6), p.578-584

2005

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Ranitidine does not alter adinazolam pharmacokinetics or pharmacodynamics

Journal of clinical psychopharmacology, 1992-08, Vol.12 (4), p.282-287

1992

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A study to evaluate the pharmacokinetics of oral 5-fluorouracil and eniluracil after concurrent administration to patients with refractory solid tumours and varying degrees of renal impairment (FUMA1005)

Cancer chemotherapy and pharmacology, 2003, Vol.51 (1), p.58-66

2003

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Biodiversity and Resilience of Ecosystem Functions

Trends in ecology & evolution (Amsterdam), 2015-11, Vol.30 (11), p.673-684

2015

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Species Interactions Reverse Grassland Responses to Changing Climate

Science (American Association for the Advancement of Science), 2007-02, Vol.315 (5812), p.640-642

2007

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Relationships between pazopanib exposure and clinical safety and efficacy in patients with advanced renal cell carcinoma

A Phase I Study of the Pharmacokinetic and Safety Profiles of Oral Pazopanib With a High-Fat or Low-Fat Meal in Patients With Advanced Solid Tumors

Phase I study of weekly paclitaxel in combination with pazopanib and lapatinib in advanced solid malignancies

Pazopanib exposure decreases as a result of an ifosfamide-dependent drug–drug interaction: results of a phase I study

Preclinical Modeling of Tumor Growth and Angiogenesis Inhibition to Describe Pazopanib Clinical Effects in Renal Cell Carcinoma

An Evaluation of the Drug Interaction Potential of Pazopanib, an Oral Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Inhibitor, Using a Modified Cooperstown 5+1 Cocktail in Patients With Advanced Solid Tumors

Relationships between pazopanib exposure and clinical safety and efficacy in patients with advanced renal cell carcinoma

Bile flow but not enterohepatic recirculation influences the pharmacokinetics of ranitidine in the rat

Comparison of zafirlukast (Accolate®) absorption after oral and colonic administration in humans

Regional gastrointestinal absorption of ranitidine in the rat

Gastrointestinal transit and distribution of ranitidine in the rat

Use of a pharmacokinetic model incorporating discontinuous gastrointestinal absorption to examine the occurrence of double peaks in oral concentration-time profiles

Erratum: Relationships between pazopanib exposure and clinical safety and efficacy in patients with advanced renal cell carcinoma

Changes in polyvinylpyrrolidone coil dimensions by complexation with organic anions : effect of chain length

Pazopanib and lapatinib in patients with relapsed malignant glioma: Results of a phase I/II study

A phase I study of pazopanib in patients with advanced hepatocellular carcinoma

An Evaluation of the Drug Interaction Potential of Pazopanib, an Oral Vascular Endothelial Growth Factor ReceptorTyrosine Kinase Inhibitor, Using a Modified Cooperstown 5+1 Cocktail in Patients With Advanced Solid Tumors

A phase I, open-label study of the safety and pharmacokinetics (PK) of pazopanib (P) and lapatinib (L) administered concurrently

Pharmacokinetics (PK) and tolerability of GW786034, a VEGFR tyrosine kinase inhibitor, after daily oral administration to patients with solid tumors

Pharmacokinetics (PK) and tolerability of GW786034, a VEGFR tyrosine kinase inhibitor, after daily oral administration to patients with solid tumors

The absolute bioavailability of oral vinorelbine in patients with solid tumors

Ranitidine does not alter adinazolam pharmacokinetics or pharmacodynamics

A study to evaluate the pharmacokinetics of oral 5-fluorouracil and eniluracil after concurrent administration to patients with refractory solid tumours and varying degrees of renal impairment (FUMA1005)

Biodiversity and Resilience of Ecosystem Functions

Species Interactions Reverse Grassland Responses to Changing Climate

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