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Targeting the sphingolipid metabolism to defeat pancreatic cancer cell resistance to the chemotherapeutic gemcitabine drug

Molecular cancer therapeutics, 2009-04, Vol.8 (4), p.809-820

2009

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The mucin MUC4 and its membrane partner ErbB2 regulate biological properties of human CAPAN-2 pancreatic cancer cells via different signalling pathways

PloS one, 2012-02, Vol.7 (2), p.e32232

2012

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Indium-111–Pentetreotide Scintigraphy and Somatostatin Receptor Subtype 2 Expression: New Prognostic Factors for Malignant Well-Differentiated Endocrine Tumors

Journal of clinical oncology, 2008-02, Vol.26 (6), p.963-970

2008

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Identification of biomarkers of human pancreatic adenocarcinomas by expression profiling and validation with gene expression analysis in endoscopic ultrasound-guided fine needle aspiration samples

World journal of gastroenterology : WJG, 2006-06, Vol.12 (21), p.3344

2006

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A Switch of G Protein-Coupled Receptor Binding Preference from Phosphoinositide 3-Kinase (PI3K)–p85 to Filamin A Negatively Controls the PI3K Pathway

Molecular and Cellular Biology, 2012-03, Vol.32 (5), p.1004-1016

2012

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NAD(P)H Quinone-Oxydoreductase 1 Protects Eukaryotic Translation Initiation Factor 4GI from Degradation by the Proteasome

Molecular and Cellular Biology, 2010-02, Vol.30 (4), p.1097-1105

2010

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sst2 Somatostatin Receptor Inhibits Cell Proliferation through Ras-, Rap1-, and B-Raf-dependent ERK2 Activation

The Journal of biological chemistry, 2003-10, Vol.278 (41), p.39356-39371

2003

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Control of contact-inhibition by 4E-BP1 upregulation

Cell cycle (Georgetown, Tex.), 2010-04, Vol.9 (7), p.1241-1245

2010

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Thrombospondin-1 is a critical effector of oncosuppressive activity of sst2 somatostatin receptor on pancreatic cancer

Proceedings of the National Academy of Sciences - PNAS, 2009-10, Vol.106 (42), p.17769-17774

2009

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Identification of an Upstream Promoter of the Human Somatostatin Receptor, hSSTR2, Which Is Controlled by Epigenetic Modifications

Endocrinology (Philadelphia), 2008-06, Vol.149 (6), p.3137-3147

2008

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Restoration of Functional Gap Junctions through Internal Ribosome Entry Site-Dependent Synthesis of Endogenous Connexins in Density-Inhibited Cancer Cells

Molecular and Cellular Biology, 2005-05, Vol.25 (10), p.4034-4045

2005

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Somatostatin Receptor Subtype 2 Sensitizes Human Pancreatic Cancer Cells to Death Ligand-Induced Apoptosis

Proceedings of the National Academy of Sciences - PNAS, 2003-01, Vol.100 (1), p.155-160

2003

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Inhibitory roles for SHP-1 and SOCS-3 following pituitary proopiomelanocortin induction by leukemia inhibitory factor

The Journal of clinical investigation, 1999-11, Vol.104 (9), p.1277-1285

1999

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The rat tyrosine phosphatase η increases cell adhesion by activating c-Src through dephosphorylation of its inhibitory phosphotyrosine residue

Oncogene, 2005-04, Vol.24 (19), p.3187-3195

2005

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Critical role of Src and SHP-2 in sst2 somatostatin receptor-mediated activation of SHP-1 and inhibition of cell proliferation

Molecular biology of the cell, 2003-09, Vol.14 (9), p.3911-3928

2003

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Angiotensin II type 2 receptors mediate inhibition of mitogen-activated protein kinase cascade and functional activation of SHP-1 tyrosine phosphatase

Biochemical journal, 1997-07, Vol.325 ( Pt 2) (2), p.449-454

1997

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A Novel Protein-Protein Interaction between a G Protein-coupled Receptor and the Phosphatase SHP-2 Is Involved in Bradykinin-induced Inhibition of Cell Proliferation

The Journal of biological chemistry, 2002-10, Vol.277 (43), p.40375-40383

2002

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Regulation of Neuronal Nitric-oxide Synthase Activity by Somatostatin Analogs following SST5 Somatostatin Receptor Activation

The Journal of biological chemistry, 2006-07, Vol.281 (28), p.19156-19171

2006

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Inhibition of Growth and Metastatic Progression of Pancreatic Carcinoma in Hamster after Somatostatin Receptor Subtype 2 (sst2) Gene Expression and Administration of Cytotoxic Somatostatin Analog AN-238

Proceedings of the National Academy of Sciences - PNAS, 2000-08, Vol.97 (16), p.9180-9185

2000

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The Tyrosine Phosphatase SHP-1 Associates with the sst2 Somatostatin Receptor and Is an Essential Component of sst2-mediated Inhibitory Growth Signaling

The Journal of biological chemistry, 1997-09, Vol.272 (39), p.24448-24454

1997

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Antiproliferative Effect of Somatostatin and Analogs

Chemotherapy (Basel), 2001, Vol.47 (2), p.30-39

2001

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Antitumor effects of somatostatin

Molecular and cellular endocrinology, 2008-05, Vol.286 (1), p.230-237

2008

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PNL2, a New Monoclonal Antibody Directed against a Fixative-Resistant Melanocyte Antigen

Modern pathology, 2003-05, Vol.16 (5), p.481-490

2003

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Characterization of the Antiproliferative Signal Mediated by the Somatostatin Receptor Subtype sst5

Proceedings of the National Academy of Sciences - PNAS, 1997-08, Vol.94 (17), p.9343-9348

1997

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sst2 Somatostatin Receptor Mediates Negative Regulation of Insulin Receptor Signaling through the Tyrosine Phosphatase SHP-1

The Journal of biological chemistry, 1998-03, Vol.273 (12), p.7099-7106

1998

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Targeting the sphingolipid metabolism to defeat pancreatic cancer cell resistance to the chemotherapeutic gemcitabine drug

The mucin MUC4 and its membrane partner ErbB2 regulate biological properties of human CAPAN-2 pancreatic cancer cells via different signalling pathways

Indium-111–Pentetreotide Scintigraphy and Somatostatin Receptor Subtype 2 Expression: New Prognostic Factors for Malignant Well-Differentiated Endocrine Tumors

Identification of biomarkers of human pancreatic adenocarcinomas by expression profiling and validation with gene expression analysis in endoscopic ultrasound-guided fine needle aspiration samples

A Switch of G Protein-Coupled Receptor Binding Preference from Phosphoinositide 3-Kinase (PI3K)–p85 to Filamin A Negatively Controls the PI3K Pathway

NAD(P)H Quinone-Oxydoreductase 1 Protects Eukaryotic Translation Initiation Factor 4GI from Degradation by the Proteasome

sst2 Somatostatin Receptor Inhibits Cell Proliferation through Ras-, Rap1-, and B-Raf-dependent ERK2 Activation

Control of contact-inhibition by 4E-BP1 upregulation

Thrombospondin-1 is a critical effector of oncosuppressive activity of sst2 somatostatin receptor on pancreatic cancer

Identification of an Upstream Promoter of the Human Somatostatin Receptor, hSSTR2, Which Is Controlled by Epigenetic Modifications

Restoration of Functional Gap Junctions through Internal Ribosome Entry Site-Dependent Synthesis of Endogenous Connexins in Density-Inhibited Cancer Cells

Somatostatin Receptor Subtype 2 Sensitizes Human Pancreatic Cancer Cells to Death Ligand-Induced Apoptosis

Inhibitory roles for SHP-1 and SOCS-3 following pituitary proopiomelanocortin induction by leukemia inhibitory factor

The rat tyrosine phosphatase η increases cell adhesion by activating c-Src through dephosphorylation of its inhibitory phosphotyrosine residue

Critical role of Src and SHP-2 in sst2 somatostatin receptor-mediated activation of SHP-1 and inhibition of cell proliferation

Angiotensin II type 2 receptors mediate inhibition of mitogen-activated protein kinase cascade and functional activation of SHP-1 tyrosine phosphatase

A Novel Protein-Protein Interaction between a G Protein-coupled Receptor and the Phosphatase SHP-2 Is Involved in Bradykinin-induced Inhibition of Cell Proliferation

Regulation of Neuronal Nitric-oxide Synthase Activity by Somatostatin Analogs following SST5 Somatostatin Receptor Activation

Inhibition of Growth and Metastatic Progression of Pancreatic Carcinoma in Hamster after Somatostatin Receptor Subtype 2 (sst2) Gene Expression and Administration of Cytotoxic Somatostatin Analog AN-238

The Tyrosine Phosphatase SHP-1 Associates with the sst2 Somatostatin Receptor and Is an Essential Component of sst2-mediated Inhibitory Growth Signaling

Antiproliferative Effect of Somatostatin and Analogs

Antitumor effects of somatostatin

PNL2, a New Monoclonal Antibody Directed against a Fixative-Resistant Melanocyte Antigen

Characterization of the Antiproliferative Signal Mediated by the Somatostatin Receptor Subtype sst5

sst2 Somatostatin Receptor Mediates Negative Regulation of Insulin Receptor Signaling through the Tyrosine Phosphatase SHP-1

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