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ARRY-520, a Novel KSP Inhibitor with Potent Activity in Hematological and Taxane-resistant Tumor Models

Anticancer research, 2009-11, Vol.29 (11), p.4373-4380

2009

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Inflammatory Biomarkers of Sulfur Mustard Analog 2-Chloroethyl Ethyl Sulfide–Induced Skin Injury in SKH-1 Hairless Mice

Toxicological sciences, 2009-03, Vol.108 (1), p.194-206

2009

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Spirocyclic β‑Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitors: From Hit to Lowering of Cerebrospinal Fluid (CSF) Amyloid β in a Higher Species

Journal of medicinal chemistry, 2013-04, Vol.56 (8), p.3379-3403

2013

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Highly potent and selective 3-N-methylquinazoline-4(3H)-one based inhibitors of B-Raf(V600E) kinase

Bioorganic & medicinal chemistry letters, 2014-04, Vol.24 (8), p.1923-1927

2014

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8‑Tetrahydropyran-2-yl Chromans: Highly Selective Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitors

Journal of medicinal chemistry, 2014-12, Vol.57 (23), p.10112-10129

2014

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Synthesis, characterization, and PK/PD studies of a series of spirocyclic pyranochromene BACE1 inhibitors

Bioorganic & medicinal chemistry letters, 2014-06, Vol.24 (11), p.2477-2480

2014

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Highly potent and selective 3-N-methylquinazoline-4(3H)-one based inhibitors of B-RafV600E kinase

Bioorganic & medicinal chemistry letters, 2014-04, Vol.24 (8), p.1923-1927

2014

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Highly potent and selective 3-N-methylquinazoline-4(3H)-one based inhibitors of B-Raf super(V600E) kinase

Bioorganic & medicinal chemistry letters, 2014-04, Vol.24 (8), p.1923-1927

2014

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Abstract 2514: ARRY-162, A Potent and Selective MEK 1/2 Inhibitor, Shows Enhanced Efficacy in Combination with Other Targeted Kinase Inhibitors and with Chemotherapy

Cancer research (Chicago, Ill.), 2010-04, Vol.70 (8_Supplement), p.2514-2514

2010

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Combination of the KSP Inhibitor ARRY-520 with Bortezomib or Revlimid Causes Sustained Tumor Regressions and Significantly Increased Time to Regrowth in Models of Multiple Myeloma

Blood, 2009-11, Vol.114 (22), p.2858-2858

2009

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Discovery of a Novel Class of Imidazo[1,2‑a]Pyridines with Potent PDGFR Activity and Oral Bioavailability

ACS medicinal chemistry letters, 2014-01, Vol.5 (1), p.78-83

2014

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Abstract 2515: Preclinical Development of ARRY-162, A Potent and Selective MEK 1/2 Inhibitor

Cancer research (Chicago, Ill.), 2010-04, Vol.70 (8_Supplement), p.2515-2515

2010

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The discovery of potent and selective pyridopyrimidin-7-one based inhibitors of B-RafV600E kinase

Bioorganic & medicinal chemistry letters, 2012-05, Vol.22 (10), p.3387-3391

2012

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Evaluation of the Denture Impact on the Palatal Rugae: An Original Research

Journal of pharmacy & bioallied science, 2023-07, Vol.15 (5), p.S224-S229

2023

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The Conundrum of Patients With Compensated Cirrhosis Requiring Kidney Transplantation; Kidney Alone or Simultaneous Liver Kidney Transplantation

Transplantation, 2023-02, Vol.107 (2), p.429-437

2023

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18F-FDG PET/CT in left ventricular assist device infections: In-depth characterization and clinical implications

The Journal of heart and lung transplantation, 2024-04, Vol.43 (4), p.529-538

2024

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On differentiation between vasogenic edema and non-enhancing tumor in high-grade glioma patients using a support vector machine classifier based upon pre and post-surgery MRI images

European journal of radiology, 2018-09, Vol.106, p.199-208

2018

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Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013

The Lancet (British edition), 2015, Vol.386 (9995), p.743-800

2015

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Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks in 188 countries, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013

The Lancet (British edition), 2015, Vol.386 (10010), p.2287-2323

2015

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Circulating MicroRNAs: Diagnostic Value as Biomarkers in the Detection of Non-alcoholic Fatty Liver Diseases and Hepatocellular Carcinoma

MicroRNA, 2023-01, Vol.12 (2), p.99-113

2023

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A NOVEL DESIGN OF COMPACT MONOPOLE ANTENNA WITH DEFECTED GROUND PLANE FOR WIDEBAND APPLICATIONS

Progress in electromagnetics research M Pier M, 2018, Vol.70, p.21-31

2018

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ARRY-520, a Novel KSP Inhibitor with Potent Activity in Hematological and Taxane-resistant Tumor Models

Inflammatory Biomarkers of Sulfur Mustard Analog 2-Chloroethyl Ethyl Sulfide–Induced Skin Injury in SKH-1 Hairless Mice

Spirocyclic β‑Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitors: From Hit to Lowering of Cerebrospinal Fluid (CSF) Amyloid β in a Higher Species

Pyrazolopyridine Inhibitors of B-RafV600E. Part 1: The Development of Selective, Orally Bioavailable, and Efficacious Inhibitors

Discovery of 7‑Tetrahydropyran-2-yl Chromans: β‑Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitors That Reduce Amyloid β‑Protein (Aβ) in the Central Nervous System

Highly potent and selective 3-N-methylquinazoline-4(3H)-one based inhibitors of B-Raf(V600E) kinase

8‑Tetrahydropyran-2-yl Chromans: Highly Selective Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitors

Synthesis, characterization, and PK/PD studies of a series of spirocyclic pyranochromene BACE1 inhibitors

Highly potent and selective 3-N-methylquinazoline-4(3H)-one based inhibitors of B-RafV600E kinase

Highly potent and selective 3-N-methylquinazoline-4(3H)-one based inhibitors of B-Raf super(V600E) kinase

Abstract 2514: ARRY-162, A Potent and Selective MEK 1/2 Inhibitor, Shows Enhanced Efficacy in Combination with Other Targeted Kinase Inhibitors and with Chemotherapy

Pyrazolopyridine Inhibitors of B-Raf(V600E). Part 1: The Development of Selective, Orally Bioavailable, and Efficacious Inhibitors

Combination of the KSP Inhibitor ARRY-520 with Bortezomib or Revlimid Causes Sustained Tumor Regressions and Significantly Increased Time to Regrowth in Models of Multiple Myeloma

Discovery of a Novel Class of Imidazo[1,2‑a]Pyridines with Potent PDGFR Activity and Oral Bioavailability

Abstract 2515: Preclinical Development of ARRY-162, A Potent and Selective MEK 1/2 Inhibitor

The discovery of potent and selective pyridopyrimidin-7-one based inhibitors of B-RafV600E kinase

Pyrazolopyridine Inhibitors of B-Raf V600E . Part 1: The Development of Selective, Orally Bioavailable, and Efficacious Inhibitors

Evaluation of the Denture Impact on the Palatal Rugae: An Original Research

The Conundrum of Patients With Compensated Cirrhosis Requiring Kidney Transplantation; Kidney Alone or Simultaneous Liver Kidney Transplantation

18F-FDG PET/CT in left ventricular assist device infections: In-depth characterization and clinical implications

On differentiation between vasogenic edema and non-enhancing tumor in high-grade glioma patients using a support vector machine classifier based upon pre and post-surgery MRI images

Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013

Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks in 188 countries, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013

Circulating MicroRNAs: Diagnostic Value as Biomarkers in the Detection of Non-alcoholic Fatty Liver Diseases and Hepatocellular Carcinoma

A NOVEL DESIGN OF COMPACT MONOPOLE ANTENNA WITH DEFECTED GROUND PLANE FOR WIDEBAND APPLICATIONS

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