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In Vitro and In Vivo Antibacterial Activities of a Novel Glycylcycline, the 9-t-Butylglycylamido Derivative of Minocycline (GAR-936)

Antimicrobial Agents and Chemotherapy, 1999-04, Vol.43 (4), p.738-744

1999

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In Vitro and In Vivo Activities of Tigecycline (GAR-936), Daptomycin, and Comparative Antimicrobial Agents against Glycopeptide-Intermediate Staphylococcus aureus and Other Resistant Gram-Positive Pathogens

Antimicrobial Agents and Chemotherapy, 2002-08, Vol.46 (8), p.2595-2601

2002

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Synthesis and structure-activity relationship of novel glycylcycline derivatives leading to the discovery of GAR-936

Bioorganic & medicinal chemistry letters, 1999-05, Vol.9 (10), p.1459-1462

1999

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Recent developments in tetracycline antibiotics

Current pharmaceutical design, 1998-04, Vol.4 (2), p.119

1998

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In vitro and in vivo antibacterial activities of the glycylcyclines, a new class of semisynthetic tetracyclines

Antimicrobial Agents and Chemotherapy, 1993-11, Vol.37 (11), p.2270-2277

1993

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Glycylcyclines. 1. A new generation of potent antibacterial agents through modification of 9-aminotetracyclines

Journal of medicinal chemistry, 1994-01, Vol.37 (1), p.184-188

1994

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Tetracycline Analogs Affecting Binding to Tn10-Encoded Tet Repressor Trigger the Same Mechanism of Induction

Biochemistry (Easton), 1996-06, Vol.35 (23), p.7439-7446

1996

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089 SELECTIVE AGGRECANASE INHIBITION IS DISEASE MODIFYING AND PAIN ALLEVIATING IN A RAT MENISCAL TEAR MODEL OF OSTEOARTHRITIS

Osteoarthritis and cartilage, 2009, Vol.17, p.S56-S56

2009

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364 SELECTIVE INHIBITION OF AGGRECANASE PREVENTS AGGRECAN DEGRADATION AND PROMOTES INCORPORATION OF NEWLY SYNTHESIZED AGGRECAN INTO THE EXTRACELLULAR MATRIX OF HUMAN OSTEOARTHRITIC CARTILAGE

Osteoarthritis and cartilage, 2007, Vol.15, p.C202-C202

2007

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Synthetic studies directed toward the naturally occurring acyl tetramic acids. 1. Convergent total synthesis of (.+-.)-tirandamycin A

Journal of the American Chemical Society, 1986-09, Vol.108 (18), p.5549-5559

1986

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Analogs of platelet activating factor (PAF). 1. Some modifications of the alkoxy chain

Journal of medicinal chemistry, 1984-09, Vol.27 (9), p.1174-1181

1984

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Political Orientations and Behavior of Public Employees: A Cross-National Comparison

Journal of public administration research and theory, 2009-10, Vol.19 (4), p.709-730

2009

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Crystal structure of the tet repressor in complex with a novel tetracycline, 9-(N,N-dimethylglycylamido)- 6-demethyl-6-deoxy-tetracycline

Journal of molecular biology, 1999-01, Vol.285 (2), p.455-461

1999

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Analogs of platelet activating factor. 4. Some modifications of the phosphocholine moiety

Journal of medicinal chemistry, 1986-03, Vol.29 (3), p.328-333

1986

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Efflux-Mediated Resistance to Tigecycline (GAR-936) in Pseudomonas aeruginosa PAO1

Antimicrobial Agents and Chemotherapy, 2003-03, Vol.47 (3), p.972-978

2003

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Case studies in current drug development: ‘glycylcyclines’

Current opinion in chemical biology, 2006-08, Vol.10 (4), p.374-379

Sum, Phaik-Eng

2006

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Analogs of platelet activating factor (PAF). 2. Some modifications of the glycerine backbone

Journal of medicinal chemistry, 1985-09, Vol.28 (9), p.1181-1187

1985

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Synthesis and biological evaluation of biphenylsulfonamide carboxylate aggrecanase-1 inhibitors

Bioorganic & medicinal chemistry letters, 2006-01, Vol.16 (2), p.311-316

2006

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Hydrophobic Acetal and Ketal Derivatives of Mannopeptimycin-α and Desmethylhexahydromannopeptimycin-α: Semisynthetic Glycopeptides with Potent Activity Against Gram-Positive Bacteria

Journal of medicinal chemistry, 2004-07, Vol.47 (14), p.3487-3490

2004

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Synthesis and antibacterial activity of 9-substituted minocycline derivatives

Bioorganic & medicinal chemistry letters, 2006-01, Vol.16 (2), p.400-403

2006

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Synthesis and activity of novel benzoxazole derivatives of mannopeptimycin glycopeptide antibiotics

Bioorganic & medicinal chemistry letters, 2003-08, Vol.13 (15), p.2607-2610

2003

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Historical Legacies, Social Capital and Civil Society: Comparing Romania on a Regional Level

Europe-Asia studies, 2005-01, Vol.57 (1), p.117-133

2005

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Synthesis and evaluation of ether and halogenated derivatives of mannopeptimycin glycopeptide antibiotics

Bioorganic & medicinal chemistry letters, 2003-08, Vol.13 (16), p.2805-2808

2003

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ChemInform Abstract: Recent Developments in Tetracycline Antibiotics

ChemInform, 1998-07, Vol.29 (27), p.no-no

1998

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Novel ether derivatives of mannopeptimycin glycopeptide antibiotic

Bioorganic & medicinal chemistry letters, 2003-03, Vol.13 (6), p.1151-1155

2003

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In Vitro and In Vivo Antibacterial Activities of a Novel Glycylcycline, the 9-t-Butylglycylamido Derivative of Minocycline (GAR-936)

In Vitro and In Vivo Activities of Tigecycline (GAR-936), Daptomycin, and Comparative Antimicrobial Agents against Glycopeptide-Intermediate Staphylococcus aureus and Other Resistant Gram-Positive Pathogens

Synthesis and structure-activity relationship of novel glycylcycline derivatives leading to the discovery of GAR-936

Recent developments in tetracycline antibiotics

In vitro and in vivo antibacterial activities of the glycylcyclines, a new class of semisynthetic tetracyclines

Glycylcyclines. 1. A new generation of potent antibacterial agents through modification of 9-aminotetracyclines

Tetracycline Analogs Affecting Binding to Tn10-Encoded Tet Repressor Trigger the Same Mechanism of Induction

089 SELECTIVE AGGRECANASE INHIBITION IS DISEASE MODIFYING AND PAIN ALLEVIATING IN A RAT MENISCAL TEAR MODEL OF OSTEOARTHRITIS

364 SELECTIVE INHIBITION OF AGGRECANASE PREVENTS AGGRECAN DEGRADATION AND PROMOTES INCORPORATION OF NEWLY SYNTHESIZED AGGRECAN INTO THE EXTRACELLULAR MATRIX OF HUMAN OSTEOARTHRITIC CARTILAGE

Synthetic studies directed toward the naturally occurring acyl tetramic acids. 1. Convergent total synthesis of (.+-.)-tirandamycin A

Analogs of platelet activating factor (PAF). 1. Some modifications of the alkoxy chain

Political Orientations and Behavior of Public Employees: A Cross-National Comparison

Crystal structure of the tet repressor in complex with a novel tetracycline, 9-(N,N-dimethylglycylamido)- 6-demethyl-6-deoxy-tetracycline

Analogs of platelet activating factor. 4. Some modifications of the phosphocholine moiety

Efflux-Mediated Resistance to Tigecycline (GAR-936) in Pseudomonas aeruginosa PAO1

Case studies in current drug development: ‘glycylcyclines’

Analogs of platelet activating factor (PAF). 2. Some modifications of the glycerine backbone

Synthesis and biological evaluation of biphenylsulfonamide carboxylate aggrecanase-1 inhibitors

Hydrophobic Acetal and Ketal Derivatives of Mannopeptimycin-α and Desmethylhexahydromannopeptimycin-α: Semisynthetic Glycopeptides with Potent Activity Against Gram-Positive Bacteria

Synthesis and antibacterial activity of 9-substituted minocycline derivatives

Synthesis and activity of novel benzoxazole derivatives of mannopeptimycin glycopeptide antibiotics

Historical Legacies, Social Capital and Civil Society: Comparing Romania on a Regional Level

Synthesis and evaluation of ether and halogenated derivatives of mannopeptimycin glycopeptide antibiotics

ChemInform Abstract: Recent Developments in Tetracycline Antibiotics

Novel ether derivatives of mannopeptimycin glycopeptide antibiotic

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