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Non-genetic heterogeneity of cells in development: more than just noise

Development (Cambridge), 2009-12, Vol.136 (23), p.3853-3862

Huang, Sui

2009

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The molecular and mathematical basis of Waddington's epigenetic landscape: A framework for post-Darwinian biology?

BioEssays, 2012-02, Vol.34 (2), p.149-157

Huang, Sui

2012

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Genetic and non-genetic instability in tumor progression: link between the fitness landscape and the epigenetic landscape of cancer cells

Cancer and metastasis reviews, 2013-12, Vol.32 (3-4), p.423-448

Huang, Sui

2013

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Towards a unification of the 2 meanings of "epigenetics"

PLoS biology, 2022-12, Vol.20 (12), p.e3001944-e3001944

Huang, Sui

2022

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Hybrid T-helper cells: stabilizing the moderate center in a polarized system

PLoS biology, 2013-08, Vol.11 (8), p.e1001632-e1001632

Huang, Sui

2013

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Where to Go: Breaking the Symmetry in Cell Motility

PLoS biology, 2016-05, Vol.14 (5), p.e1002463-e1002463

Huang, Sui

2016

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Cell lineage determination in state space: a systems view brings flexibility to dogmatic canonical rules

PLoS biology, 2010-05, Vol.8 (5), p.e1000380-e1000380

Huang, Sui

2010

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Understanding gene circuits at cell-fate branch points for rational cell reprogramming

Trends in genetics, 2011-02, Vol.27 (2), p.55-62

2011

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Transcriptome-wide noise controls lineage choice in mammalian progenitor cells

Nature, 2008-05, Vol.453 (7194), p.544-547

2008

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The Potential Landscape of Genetic Circuits Imposes the Arrow of Time in Stem Cell Differentiation

Biophysical journal, 2010-07, Vol.99 (1), p.29-39

2010

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How to escape the cancer attractor: Rationale and limitations of multi-target drugs

Seminars in cancer biology, 2013-08, Vol.23 (4), p.270-278

2013

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Alpha-lipoic acid protects against aortic aneurysm and dissection by improving vascular smooth muscle cell function

Life sciences (1973), 2022-12, Vol.311, p.121159-121159, Article 121159

2022

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Non-Darwinian dynamics in therapy-induced cancer drug resistance

Nature communications, 2013-09, Vol.4 (1), p.2467-2467, Article 2467

2013

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Stemness of the hybrid Epithelial/Mesenchymal State in Breast Cancer and Its Association with Poor Survival

PloS one, 2015-05, Vol.10 (5), p.e0126522-e0126522

2015

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A model for the intrinsic limit of cancer therapy: Duality of treatment-induced cell death and treatment-induced stemness

PLoS computational biology, 2022-07, Vol.18 (7), p.e1010319

2022

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Careful selection of reference genes is required for reliable performance of RT-qPCR in human normal and cancer cell lines

PloS one, 2013-03, Vol.8 (3), p.e59180-e59180

2013

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Self-Generated Chemoattractant Gradients: Attractant Depletion Extends the Range and Robustness of Chemotaxis

PLoS biology, 2016-03, Vol.14 (3), p.e1002404-e1002404

2016

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Cell Fate Decision as High-Dimensional Critical State Transition

PLoS biology, 2016-12, Vol.14 (12), p.e2000640-e2000640

2016

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The perinucleolar compartment: structure, function, and utility in anti-cancer drug development

Nucleus (Austin, Tex.), 2024-12, Vol.15 (1), p.2306777

2024

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A Becn1 mutation mediates hyperactive autophagic sequestration of amyloid oligomers and improved cognition in Alzheimer's disease

PLoS genetics, 2017-08, Vol.13 (8), p.e1006962-e1006962

2017

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Resolvins suppress tumor growth and enhance cancer therapy

The Journal of experimental medicine, 2018-01, Vol.215 (1), p.115-140

2018

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Criticality is an emergent property of genetic networks that exhibit evolvability

PLoS computational biology, 2012-09, Vol.8 (9), p.e1002669-e1002669

2012

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Suppression of chemotherapy-induced cytokine/lipid mediator surge and ovarian cancer by a dual COX-2/sEH inhibitor

Proceedings of the National Academy of Sciences - PNAS, 2019-01, Vol.116 (5), p.1698-1703

2019

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Recurrent functional misinterpretation of RNA-seq data caused by sample-specific gene length bias

PLoS biology, 2019-11, Vol.17 (11), p.e3000481-e3000481

2019

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Regulation of inflammation in cancer by eicosanoids

Prostaglandins & other lipid mediators, 2011-11, Vol.96 (1), p.27-36

2011

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Non-genetic heterogeneity of cells in development: more than just noise

The molecular and mathematical basis of Waddington's epigenetic landscape: A framework for post-Darwinian biology?

Genetic and non-genetic instability in tumor progression: link between the fitness landscape and the epigenetic landscape of cancer cells

Towards a unification of the 2 meanings of "epigenetics"

Hybrid T-helper cells: stabilizing the moderate center in a polarized system

Where to Go: Breaking the Symmetry in Cell Motility

Cell lineage determination in state space: a systems view brings flexibility to dogmatic canonical rules

Understanding gene circuits at cell-fate branch points for rational cell reprogramming

Transcriptome-wide noise controls lineage choice in mammalian progenitor cells

The Potential Landscape of Genetic Circuits Imposes the Arrow of Time in Stem Cell Differentiation

How to escape the cancer attractor: Rationale and limitations of multi-target drugs

Alpha-lipoic acid protects against aortic aneurysm and dissection by improving vascular smooth muscle cell function

Non-Darwinian dynamics in therapy-induced cancer drug resistance

Stemness of the hybrid Epithelial/Mesenchymal State in Breast Cancer and Its Association with Poor Survival

A model for the intrinsic limit of cancer therapy: Duality of treatment-induced cell death and treatment-induced stemness

Careful selection of reference genes is required for reliable performance of RT-qPCR in human normal and cancer cell lines

Self-Generated Chemoattractant Gradients: Attractant Depletion Extends the Range and Robustness of Chemotaxis

Cell Fate Decision as High-Dimensional Critical State Transition

The perinucleolar compartment: structure, function, and utility in anti-cancer drug development

A Becn1 mutation mediates hyperactive autophagic sequestration of amyloid oligomers and improved cognition in Alzheimer's disease

Resolvins suppress tumor growth and enhance cancer therapy

Criticality is an emergent property of genetic networks that exhibit evolvability

Suppression of chemotherapy-induced cytokine/lipid mediator surge and ovarian cancer by a dual COX-2/sEH inhibitor

Recurrent functional misinterpretation of RNA-seq data caused by sample-specific gene length bias

Regulation of inflammation in cancer by eicosanoids

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