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The Additive Effects of Low Dose Intake of Ferulic Acid, Phosphatidylserine and Curcumin, Not Alone, Improve Cognitive Function in APPswe/PS1dE9 Transgenic Mice

Biological and Pharmaceutical Bulletin, 2019/10/01, Vol.42(10), pp.1694-1706

2019

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The new approach in development of anti-Alzheimer's disease drugs via the cholinergic hypothesis

Chemico-biological interactions, 2008-09, Vol.175 (1), p.204-208

Sugimoto, Hachiro

2008

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Aromatherapy improves cognitive dysfunction in senescence-accelerated mouse prone 8 by reducing the level of amyloid beta and tau phosphorylation

PloS one, 2020-10, Vol.15 (10), p.e0240378-e0240378

2020

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Flavonols and flavones as BACE-1 inhibitors: Structure–activity relationship in cell-free, cell-based and in silico studies reveal novel pharmacophore features

Biochimica et biophysica acta, 2008-05, Vol.1780 (5), p.819-825

2008

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Glutathione Biosynthesis via Activation of the Nuclear Factor E2–Related Factor 2 (Nrf2) – Antioxidant-Response Element (ARE) Pathway Is Essential for Neuroprotective Effects of Sulforaphane and 6-(Methylsulfinyl) Hexyl Isothiocyanate

Journal of Pharmacological Sciences, 2011, Vol.115(3), pp.320-328

2011

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The Additive Effects of Low Dose Intake of Ferulic Acid, Phosphatidylserine and Curcumin, Not Alone, Improve Cognitive Function in APPswe/PS1dE9 Transgenic Mice

Biological and Pharmaceutical Bulletin, 2019-10, Vol.42 (10), p.1694-1706

2019

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Acetylcholinesterase inhibitors used in treatment of Alzheimer's disease prevent glutamate neurotoxicity via nicotinic acetylcholine receptors and phosphatidylinositol 3-kinase cascade

Neuropharmacology, 2006-09, Vol.51 (3), p.474-486

2006

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Development of a brain-permeable peptide nanofiber that prevents aggregation of Alzheimer pathogenic proteins

PloS one, 2020-07, Vol.15 (7), p.e0235979-e0235979

2020

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LGI1 and LGI4 bind to ADAM22, ADAM23 and ADAM11

International journal of biological sciences, 2008-01, Vol.4 (6), p.387-396

2008

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Three distinct neuroprotective functions of myricetin against glutamate-induced neuronal cell death: Involvement of direct inhibition of caspase-3

Journal of neuroscience research, 2008-06, Vol.86 (8), p.1836-1845

2008

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Therapeutic effect of a novel curcumin derivative GT863 on a mouse model of amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis and frontotemporal degeneration, 2022-10, Vol.23 (7-8), p.489-495

2022

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Invasion Precedes Tumor Mass Formation in a Malignant Brain Tumor Model of Genetically Modified Neural Stem Cells

Neoplasia (New York, N.Y.), 2011-09, Vol.13 (9), p.784-IN3

2011

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PE859, a novel tau aggregation inhibitor, reduces aggregated tau and prevents onset and progression of neural dysfunction in vivo

PloS one, 2015-02, Vol.10 (2), p.e0117511-e0117511

2015

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Long-Term Ultra-High Hydrostatic Pressurized Brown Rice Intake Prevents Bone Mineral Density Decline in Elderly Japanese Individuals

Journal of Nutritional Science and Vitaminology, 2019/10/11, Vol.65(Supplement), pp.S88-S92

2019

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Isolation, identification, and biological evaluation of Nrf2-ARE activator from the leaves of green perilla (Perilla frutescens var. crispa f. viridis)

Free radical biology & medicine, 2012-08, Vol.53 (4), p.669-679

2012

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Influence of Ultra-High Hydrostatic Pressurizing Brown Rice on Cognitive Functions and Mental Health of Elderly Japanese Individuals: A 2-Year Randomized and Controlled Trial

Journal of Nutritional Science and Vitaminology, 2019/10/11, Vol.65(Supplement), pp.S80-S87

2019

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Curcumin Derivative GT863 Inhibits Amyloid-Beta Production via Inhibition of Protein N-Glycosylation

Cells (Basel, Switzerland), 2020-02, Vol.9 (2), p.349

2020

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Amyloid precursor protein promotes endoplasmic reticulum stress‐induced cell death via C/EBP homologous protein‐mediated pathway

Journal of neurochemistry, 2009-06, Vol.109 (5), p.1324-1337

2009

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Decreased proliferation of hippocampal progenitor cells in APPswe/PS1dE9 transgenic mice

Neuroreport, 2007-11, Vol.18 (17), p.1801-1805

2007

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Rac1 inhibition negatively regulates transcriptional activity of the amyloid precursor protein gene

Journal of neuroscience research, 2009-07, Vol.87 (9), p.2105-2114

2009

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Donepezil hydrochloride (E2020) and other acetylcholinesterase inhibitors

Current medicinal chemistry, 2000-03, Vol.7 (3), p.303-339

2000

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Distinct mechanisms underlie distinct polyphenol-induced neuroprotection

FEBS letters, 2006-12, Vol.580 (28), p.6623-6628

2006

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Nicotinic acetylcholine receptor-mediated neuroprotection by donepezil against glutamate neurotoxicity in rat cortical neurons

The Journal of pharmacology and experimental therapeutics, 2003-08, Vol.306 (2), p.772-777

2003

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Characterization of sequential N-cadherin cleavage by ADAM10 and PS1

Neuroscience letters, 2006-07, Vol.402 (3), p.278-283

2006

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Integrin-associated protein promotes neuronal differentiation of neural stem/progenitor cells

PloS one, 2015-02, Vol.10 (2), p.e0116741-e0116741

2015

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The Additive Effects of Low Dose Intake of Ferulic Acid, Phosphatidylserine and Curcumin, Not Alone, Improve Cognitive Function in APPswe/PS1dE9 Transgenic Mice

The new approach in development of anti-Alzheimer's disease drugs via the cholinergic hypothesis

Aromatherapy improves cognitive dysfunction in senescence-accelerated mouse prone 8 by reducing the level of amyloid beta and tau phosphorylation

Flavonols and flavones as BACE-1 inhibitors: Structure–activity relationship in cell-free, cell-based and in silico studies reveal novel pharmacophore features

Glutathione Biosynthesis via Activation of the Nuclear Factor E2–Related Factor 2 (Nrf2) – Antioxidant-Response Element (ARE) Pathway Is Essential for Neuroprotective Effects of Sulforaphane and 6-(Methylsulfinyl) Hexyl Isothiocyanate

The Additive Effects of Low Dose Intake of Ferulic Acid, Phosphatidylserine and Curcumin, Not Alone, Improve Cognitive Function in APPswe/PS1dE9 Transgenic Mice

Acetylcholinesterase inhibitors used in treatment of Alzheimer's disease prevent glutamate neurotoxicity via nicotinic acetylcholine receptors and phosphatidylinositol 3-kinase cascade

Development of a brain-permeable peptide nanofiber that prevents aggregation of Alzheimer pathogenic proteins

LGI1 and LGI4 bind to ADAM22, ADAM23 and ADAM11

Three distinct neuroprotective functions of myricetin against glutamate-induced neuronal cell death: Involvement of direct inhibition of caspase-3

Therapeutic effect of a novel curcumin derivative GT863 on a mouse model of amyotrophic lateral sclerosis

Invasion Precedes Tumor Mass Formation in a Malignant Brain Tumor Model of Genetically Modified Neural Stem Cells

PE859, a novel tau aggregation inhibitor, reduces aggregated tau and prevents onset and progression of neural dysfunction in vivo

Long-Term Ultra-High Hydrostatic Pressurized Brown Rice Intake Prevents Bone Mineral Density Decline in Elderly Japanese Individuals

Isolation, identification, and biological evaluation of Nrf2-ARE activator from the leaves of green perilla (Perilla frutescens var. crispa f. viridis)

Influence of Ultra-High Hydrostatic Pressurizing Brown Rice on Cognitive Functions and Mental Health of Elderly Japanese Individuals: A 2-Year Randomized and Controlled Trial

Curcumin Derivative GT863 Inhibits Amyloid-Beta Production via Inhibition of Protein N-Glycosylation

Amyloid precursor protein promotes endoplasmic reticulum stress‐induced cell death via C/EBP homologous protein‐mediated pathway

Decreased proliferation of hippocampal progenitor cells in APPswe/PS1dE9 transgenic mice

Rac1 inhibition negatively regulates transcriptional activity of the amyloid precursor protein gene

Donepezil hydrochloride (E2020) and other acetylcholinesterase inhibitors

Distinct mechanisms underlie distinct polyphenol-induced neuroprotection

Nicotinic acetylcholine receptor-mediated neuroprotection by donepezil against glutamate neurotoxicity in rat cortical neurons

Characterization of sequential N-cadherin cleavage by ADAM10 and PS1

Integrin-associated protein promotes neuronal differentiation of neural stem/progenitor cells

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