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Human Endotoxin Administration as an Experimental Model in Drug Development

Clinical pharmacology and therapeutics, 2014-10, Vol.96 (4), p.418-422

2014

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The Standardized Mortality Ratio and ICU Benchmarking: An Old Measure That Is Still Missing the Mark

Critical care medicine, 2024-03, Vol.52 (3), p.498-501

Suffredini, Dante A

2024

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The Long Road to Normalcy Following Survival From COVID-19-Associated Acute Respiratory Distress Syndrome

Critical care medicine, 2021-11, Vol.49 (11), p.1996-1999

Suffredini, Dante A

2021

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The Potential Pathogenic Contributions of Endothelial Barrier and Arterial Contractile Dysfunction to Shock Due to B. anthracis Lethal and Edema Toxins

Toxins, 2017-12, Vol.9 (12), p.394

2017

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Pulmonary tumor thrombotic microangiopathy and pulmonary veno-occlusive disease in a woman with cervical cancer treated with cediranib and durvalumab

BMC pulmonary medicine, 2018-07, Vol.18 (1), p.112-112, Article 112

2018

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Impact of Adjuvant Use of Midodrine to Intravenous Vasopressors: A Systematic Review and Meta-Analysis

Critical care research and practice, 2021-05, Vol.2021, p.5588483-9

2021

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Local Inflammatory Responses following Bronchial Endotoxin Instillation in Humans

American journal of respiratory and critical care medicine, 2001-06, Vol.163 (7), p.1591-1598

2001

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Does Bacillus anthracis Lethal Toxin Directly Depress Myocardial Function? A Review of Clinical Cases and Preclinical Studies

Toxins, 2015-12, Vol.7 (12), p.5417-5434

2015

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Hydrocortisone decreases lethality and inflammatory cytokine and nitric oxide production in rats challenged with B. anthracis cell wall peptidoglycan

Intensive care medicine experimental, 2020-11, Vol.8 (1), p.67-67, Article 67

2020

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New insights into the biology of the acute phase response

Journal of clinical immunology, 1999-07, Vol.19 (4), p.203-214

1999

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A Rationale for Use of High Flow Nasal Cannula for Select Patients With Suspected or Confirmed Severe Acute Respiratory Syndrome Coronavirus-2 Infection

Journal of Intensive Care Medicine, 2021-01, Vol.36 (1), p.9-17

2021

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Enhanced cytotoxicity of allogeneic NK cells with killer immunoglobulin-like receptor ligand incompatibility against melanoma and renal cell carcinoma cells

Blood, 2004-07, Vol.104 (1), p.170-177

2004

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Dose-Related Inflammatory Effects of Intravenous Endotoxin in Humans: Evaluation of a New Clinical Lot of Escherichia coli O:113 Endotoxin

The Journal of infectious diseases, 1999-05, Vol.179 (5), p.1278-1282

1999

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Management of Antiretrovirals in Critically Ill Patients: Great Progress But Potential Pitfalls

Critical care medicine, 2018-05, Vol.46 (5), p.663-665

2018

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A Randomized, Controlled Trial of ZMapp for Ebola Virus Infection

The New England journal of medicine, 2016-10, Vol.375 (15), p.1448-1456

2016

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Detection of interleukin 8 and tumor necrosis factor in normal humans after intravenous endotoxin : the effect of antiinflammatory agents

The Journal of experimental medicine, 1991-04, Vol.173 (4), p.1021-1024

1991

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Gene expression profiles of peripheral blood leukocytes after endotoxin challenge in humans

Physiological genomics, 2006-04, Vol.25 (2), p.203-215

2006

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High-dose corticosteroid therapy for diffuse alveolar hemorrhage in allogeneic bone marrow stem cell transplant recipients

Bone marrow transplantation (Basingstoke), 1999-10, Vol.24 (8), p.879-883

1999

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Anthrax immune globulin improves hemodynamics and survival during B. anthracis toxin-induced shock in canines receiving titrated fluid and vasopressor support

Intensive care medicine experimental, 2017-10, Vol.5 (1), p.48-48, Article 48

2017

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Clinical Management of Ebola Virus Disease in the United States and Europe

The New England journal of medicine, 2016-02, Vol.374 (7), p.636-646

2016

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Shock and lethality with anthrax edema toxin in rats are associated with reduced arterial responsiveness to phenylephrine and are reversed with adefovir

American journal of physiology. Heart and circulatory physiology, 2017-11, Vol.313 (5), p.H946-H958

2017

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Effects of recombinant dimeric TNF receptor on human inflammatory responses following intravenous endotoxin administration

The Journal of immunology (1950), 1995-11, Vol.155 (10), p.5038-5045

1995

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The cardiovascular response of normal humans to the administration of endotoxin

The New England journal of medicine, 1989-08, Vol.321 (5), p.280-287

1989

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Parenteral irons versus transfused red blood cells for treatment of anemia during canine experimental bacterial pneumonia

Transfusion (Philadelphia, Pa.), 2017-10, Vol.57 (10), p.2338-2347

2017

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Human Neutrophils Secrete Gelatinase B In Vitro and In Vivo in Response to Endotoxin and Proinflammatory Mediators

American journal of respiratory cell and molecular biology, 1999-03, Vol.20 (3), p.458-464

1999

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Human Endotoxin Administration as an Experimental Model in Drug Development

The Standardized Mortality Ratio and ICU Benchmarking: An Old Measure That Is Still Missing the Mark

The Long Road to Normalcy Following Survival From COVID-19-Associated Acute Respiratory Distress Syndrome

The Potential Pathogenic Contributions of Endothelial Barrier and Arterial Contractile Dysfunction to Shock Due to B. anthracis Lethal and Edema Toxins

Pulmonary tumor thrombotic microangiopathy and pulmonary veno-occlusive disease in a woman with cervical cancer treated with cediranib and durvalumab

Impact of Adjuvant Use of Midodrine to Intravenous Vasopressors: A Systematic Review and Meta-Analysis

Local Inflammatory Responses following Bronchial Endotoxin Instillation in Humans

Does Bacillus anthracis Lethal Toxin Directly Depress Myocardial Function? A Review of Clinical Cases and Preclinical Studies

Hydrocortisone decreases lethality and inflammatory cytokine and nitric oxide production in rats challenged with B. anthracis cell wall peptidoglycan

New insights into the biology of the acute phase response

A Rationale for Use of High Flow Nasal Cannula for Select Patients With Suspected or Confirmed Severe Acute Respiratory Syndrome Coronavirus-2 Infection

Enhanced cytotoxicity of allogeneic NK cells with killer immunoglobulin-like receptor ligand incompatibility against melanoma and renal cell carcinoma cells

Dose-Related Inflammatory Effects of Intravenous Endotoxin in Humans: Evaluation of a New Clinical Lot of Escherichia coli O:113 Endotoxin

Management of Antiretrovirals in Critically Ill Patients: Great Progress But Potential Pitfalls

A Randomized, Controlled Trial of ZMapp for Ebola Virus Infection

Detection of interleukin 8 and tumor necrosis factor in normal humans after intravenous endotoxin : the effect of antiinflammatory agents

Gene expression profiles of peripheral blood leukocytes after endotoxin challenge in humans

High-dose corticosteroid therapy for diffuse alveolar hemorrhage in allogeneic bone marrow stem cell transplant recipients

Anthrax immune globulin improves hemodynamics and survival during B. anthracis toxin-induced shock in canines receiving titrated fluid and vasopressor support

Clinical Management of Ebola Virus Disease in the United States and Europe

Shock and lethality with anthrax edema toxin in rats are associated with reduced arterial responsiveness to phenylephrine and are reversed with adefovir

Effects of recombinant dimeric TNF receptor on human inflammatory responses following intravenous endotoxin administration

The cardiovascular response of normal humans to the administration of endotoxin

Parenteral irons versus transfused red blood cells for treatment of anemia during canine experimental bacterial pneumonia

Human Neutrophils Secrete Gelatinase B In Vitro and In Vivo in Response to Endotoxin and Proinflammatory Mediators

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