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Transcriptional noise and the fidelity of initiation by RNA polymerase II

Nature structural & molecular biology, 2007-02, Vol.14 (2), p.103-105

Struhl, Kevin

2007

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Inflammatory regulatory network mediated by the joint action of NF-kB, STAT3, and AP-1 factors is involved in many human cancers

Proceedings of the National Academy of Sciences - PNAS, 2019-05, Vol.116 (19), p.9453-9462

2019

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Selectivity of ORC binding sites and the relation to replication timing, fragile sites, and deletions in cancers

Proceedings of the National Academy of Sciences - PNAS, 2016-08, Vol.113 (33), p.E4810-E4819

2016

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Metformin inhibits the inflammatory response associated with cellular transformation and cancer stem cell growth

Proceedings of the National Academy of Sciences - PNAS, 2013-01, Vol.110 (3), p.972-977

2013

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The Cyc8-Tup1 complex inhibits transcription primarily by masking the activation domain of the recruiting protein

Genes & development, 2011-12, Vol.25 (23), p.2525-2539

2011

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Metformin Decreases the Dose of Chemotherapy for Prolonging Tumor Remission in Mouse Xenografts Involving Multiple Cancer Cell Types

Cancer research (Chicago, Ill.), 2011-05, Vol.71 (9), p.3196-3201

2011

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TFIIH Phosphorylation of the Pol II CTD Stimulates Mediator Dissociation from the Preinitiation Complex and Promoter Escape

Molecular cell, 2014-05, Vol.54 (4), p.601-612

2014

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Is DNA methylation of tumour suppressor genes epigenetic?

eLife, 2014-03, Vol.3, p.e02475-e02475

Struhl, Kevin

2014

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Inducible formation of breast cancer stem cells and their dynamic equilibrium with non-stem cancer cells via IL6 secretion

Proceedings of the National Academy of Sciences - PNAS, 2011-01, Vol.108 (4), p.1397-1402

2011

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Nutrient Deprivation Elicits a Transcriptional and Translational Inflammatory Response Coupled to Decreased Protein Synthesis

Cell reports (Cambridge), 2018-08, Vol.24 (6), p.1415-1424

2018

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Comparison of transcriptional initiation by RNA polymerase II across eukaryotic species

eLife, 2021-09, Vol.10

2021

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Global Analysis of mRNA Isoform Half-Lives Reveals Stabilizing and Destabilizing Elements in Yeast

Cell, 2014-02, Vol.156 (4), p.812-824

2014

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HBO1 histone acetylase is a coactivator of the replication licensing factor Cdt1

Genes & development, 2008-10, Vol.22 (19), p.2633-2638

2008

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STAT3 Activation of miR-21 and miR-181b-1 via PTEN and CYLD Are Part of the Epigenetic Switch Linking Inflammation to Cancer

Molecular cell, 2010-08, Vol.39 (4), p.493-506

2010

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An integrated transcriptional regulatory circuit that reinforces the breast cancer stem cell state

Proceedings of the National Academy of Sciences - PNAS, 2012-09, Vol.109 (36), p.14470-14475

2012

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S100A8/S100A9 cytokine acts as a transcriptional coactivator during breast cellular transformation

Science advances, 2021-01, Vol.7 (1)

2021

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The Ground State and Evolution of Promoter Region Directionality

Cell, 2017-08, Vol.170 (5), p.889-898.e10

2017

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Splitting of H3-H4 tetramers at transcriptionally active genes undergoing dynamic histone exchange

Proceedings of the National Academy of Sciences - PNAS, 2011-01, Vol.108 (4), p.1296-1301

2011

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Loss of miR-200 Inhibition of Suz12 Leads to Polycomb-Mediated Repression Required for the Formation and Maintenance of Cancer Stem Cells

Molecular cell, 2010-09, Vol.39 (5), p.761-772

2010

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YAP and TAZ are transcriptional co-activators of AP-1 proteins and STAT3 during breast cellular transformation

eLife, 2021-08, Vol.10

2021

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Metformin and phenformin deplete tricarboxylic acid cycle and glycolytic intermediates during cell transformation and NTPs in cancer stem cells

Proceedings of the National Academy of Sciences - PNAS, 2014-07, Vol.111 (29), p.10574-10579

2014

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MafB, WDR77, and ß-catenin interact with each other and have similar genome association profiles

PloS one, 2022-04, Vol.17 (4), p.e0264799-e0264799

2022

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Intrinsically disordered regions (IDRs): A vague and confusing concept for protein function

Molecular cell, 2024-04, Vol.84 (7), p.1186-1187

Struhl, Kevin

2024

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Non-canonical functions of enhancers: regulation of RNA polymerase III transcription, DNA replication, and V(D)J recombination

Trends in genetics, 2024-06, Vol.40 (6), p.471-479

Struhl, Kevin

2024

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Alternative to the soft-agar assay that permits high-throughput drug and genetic screens for cellular transformation

Proceedings of the National Academy of Sciences - PNAS, 2015-05, Vol.112 (18), p.5708-5713

2015

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Transcriptional noise and the fidelity of initiation by RNA polymerase II

Inflammatory regulatory network mediated by the joint action of NF-kB, STAT3, and AP-1 factors is involved in many human cancers

Selectivity of ORC binding sites and the relation to replication timing, fragile sites, and deletions in cancers

Metformin inhibits the inflammatory response associated with cellular transformation and cancer stem cell growth

The Cyc8-Tup1 complex inhibits transcription primarily by masking the activation domain of the recruiting protein

Metformin Decreases the Dose of Chemotherapy for Prolonging Tumor Remission in Mouse Xenografts Involving Multiple Cancer Cell Types

TFIIH Phosphorylation of the Pol II CTD Stimulates Mediator Dissociation from the Preinitiation Complex and Promoter Escape

Is DNA methylation of tumour suppressor genes epigenetic?

Inducible formation of breast cancer stem cells and their dynamic equilibrium with non-stem cancer cells via IL6 secretion

Nutrient Deprivation Elicits a Transcriptional and Translational Inflammatory Response Coupled to Decreased Protein Synthesis

Comparison of transcriptional initiation by RNA polymerase II across eukaryotic species

Global Analysis of mRNA Isoform Half-Lives Reveals Stabilizing and Destabilizing Elements in Yeast

HBO1 histone acetylase is a coactivator of the replication licensing factor Cdt1

STAT3 Activation of miR-21 and miR-181b-1 via PTEN and CYLD Are Part of the Epigenetic Switch Linking Inflammation to Cancer

An integrated transcriptional regulatory circuit that reinforces the breast cancer stem cell state

S100A8/S100A9 cytokine acts as a transcriptional coactivator during breast cellular transformation

The Ground State and Evolution of Promoter Region Directionality

Splitting of H3-H4 tetramers at transcriptionally active genes undergoing dynamic histone exchange

Loss of miR-200 Inhibition of Suz12 Leads to Polycomb-Mediated Repression Required for the Formation and Maintenance of Cancer Stem Cells

YAP and TAZ are transcriptional co-activators of AP-1 proteins and STAT3 during breast cellular transformation

Metformin and phenformin deplete tricarboxylic acid cycle and glycolytic intermediates during cell transformation and NTPs in cancer stem cells

MafB, WDR77, and ß-catenin interact with each other and have similar genome association profiles

Intrinsically disordered regions (IDRs): A vague and confusing concept for protein function

Non-canonical functions of enhancers: regulation of RNA polymerase III transcription, DNA replication, and V(D)J recombination

Alternative to the soft-agar assay that permits high-throughput drug and genetic screens for cellular transformation

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