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Substrate-dependent modulation of CYP3A4 catalytic activity: analysis of 27 test compounds with four fluorometric substrates

Drug metabolism and disposition, 2000-12, Vol.28 (12), p.1440

2000

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Monospecific antipeptide antibody to cytochrome P-450 2B6

Drug metabolism and disposition, 1999-04, Vol.27 (4), p.517

1999

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Concurrent flavin-containing monooxygenase down-regulation and cytochrome P-450 induction by dietary indoles in rat: implications for drug-drug interaction

Drug metabolism and disposition, 2000-08, Vol.28 (8), p.930

2000

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Mechanisms of tumor modulation by indole-3-carbinol. Disposition and excretion in male Fischer 344 rats

Drug metabolism and disposition, 1995-09, Vol.23 (9), p.965

1995

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Effects of ginseng components on c-DNA-expressed cytochrome P450 enzyme catalytic activity

Life sciences (1973), 1999, Vol.65 (15), p.PL209-PL214

1999

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Human cytochrome P450-catalyzed conversion of the proestrogenic pesticide methoxychlor into an estrogen. Role of CYP2C19 and CYP1A2 in O-demethylation

Drug metabolism and disposition, 1998-09, Vol.26 (9), p.868

1998

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In vitro and pharmacophore insights into CYP3A enzymes

Trends in pharmacological sciences (Regular ed.), 2003-04, Vol.24 (4), p.161-166

2003

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Validation of cytochrome P450 time-dependent inhibition assays: a two-time point IC50 shift approach facilitates kinact assay design

Xenobiotica, 2009-02, Vol.39 (2), p.99-112

2009

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Indole-3-carbinol and beta-naphthoflavone induction of aflatoxin B1 metabolism and cytochromes P-450 associated with bioactivation and detoxication of aflatoxin B1 in the rat

Drug metabolism and disposition, 1994-05, Vol.22 (3), p.383

1994

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The use of 3-[2-(N,N-diethyl-N-methylammonium)ethyl]-7-methoxy-4-methylcoumarin (AMMC) as a specific CYP2D6 probe in human liver microsomes

Drug metabolism and disposition, 2001-09, Vol.29 (9), p.1196

2001

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Prosubstrates of CYP3A4, the Major Human Hepatic Cytochrome P450 : Transformation into Substrates by Other p450 Isoforms

Biochemical pharmacology, 1998-06, Vol.55 (11), p.1861-1871

1998

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Cytochrome P450 fluorometric substrates: identification of isoform-selective probes for rat CYP2D2 and human CYP3A4

Drug metabolism and disposition, 2002-07, Vol.30 (7), p.845-852

2002

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A High-Throughput Screen to Identify Inhibitors of Aromatase (CYP19)

Analytical biochemistry, 2000-09, Vol.284 (2), p.427-430

2000

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Influence of β-Naphthoflavone and Methoxychlor Pretreatment on the Biotransformation and Estrogenic Activity of Methoxychlor in Channel Catfish (Ictalurus punctatus)

Toxicology and applied pharmacology, 1997-08, Vol.145 (2), p.349-356

1997

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Indole-3-carbinol induces a rat liver glutathione transferase subunit (Yc2) with high activity toward aflatoxin B1 exo-epoxide. Association with reduced levels of hepatic aflatoxin-DNA adducts in vivo

Drug metabolism and disposition, 1994-05, Vol.22 (3), p.392

1994

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Tissue-specific expression of flavin-containing monooxygenase (FMO) forms 1 and 2 in the rabbit

The Journal of pharmacology and experimental therapeutics, 1995-03, Vol.272 (3), p.1293

1995

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Biotransformation and estrogenic activity of Methoxychlor and its metabolites in channel catfish ( Ictalurus punctatus)

Marine environmental research, 1998-07, Vol.46 (1), p.159-162

1998

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Fluorometric screening for metabolism-based drug–drug interactions

Journal of pharmacological and toxicological methods, 2000-07, Vol.44 (1), p.325-331

2000

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Selective Time- and NADPH-Dependent Inhibition of Human CYP2E1 by Clomethiazole

Drug metabolism and disposition, 2016-08, Vol.44 (8), p.1424-1430

2016

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Catalytic Characteristics of CYP3A4: Requirement for a Phenolic Function in ortho Hydroxylation of Estradiol and Mono-O-demethylated Methoxychlor

Biochemistry (Easton), 1997-02, Vol.36 (8), p.2203-2210

1997

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Design and application of fluorometric assays for human cytochrome P450 inhibition

Methods in Enzymology, 2002, Vol.357, p.276-284

2002

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HIGHLY SELECTIVE INHIBITION OF HUMAN CYP3A IN VITRO BY AZAMULIN AND EVIDENCE THAT INHIBITION IS IRREVERSIBLE

Drug metabolism and disposition, 2004-01, Vol.32 (1), p.105-112

2004

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Fluorometric High-Throughput Screening for Inhibitors of Cytochrome P450

Annals of the New York Academy of Sciences, 2000-09, Vol.919 (1), p.26-32

2000

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Ring hydroxylation of [o-3H]methoxychlor as a probe for liver microsomal CYP2B activity: potential for in vivo CYP2B assay

Analytical biochemistry, 1996-01, Vol.233 (1), p.100-107

1996

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Human cytochrome p450 induction and inhibition potential of clevidipine and its primary metabolite h152/81

Drug metabolism and disposition, 2006-05, Vol.34 (5), p.734-737

2006

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Substrate-dependent modulation of CYP3A4 catalytic activity: analysis of 27 test compounds with four fluorometric substrates

Monospecific antipeptide antibody to cytochrome P-450 2B6

Concurrent flavin-containing monooxygenase down-regulation and cytochrome P-450 induction by dietary indoles in rat: implications for drug-drug interaction

Mechanisms of tumor modulation by indole-3-carbinol. Disposition and excretion in male Fischer 344 rats

Effects of ginseng components on c-DNA-expressed cytochrome P450 enzyme catalytic activity

Human cytochrome P450-catalyzed conversion of the proestrogenic pesticide methoxychlor into an estrogen. Role of CYP2C19 and CYP1A2 in O-demethylation

In vitro and pharmacophore insights into CYP3A enzymes

Validation of cytochrome P450 time-dependent inhibition assays: a two-time point IC50 shift approach facilitates kinact assay design

Indole-3-carbinol and beta-naphthoflavone induction of aflatoxin B1 metabolism and cytochromes P-450 associated with bioactivation and detoxication of aflatoxin B1 in the rat

The use of 3-[2-(N,N-diethyl-N-methylammonium)ethyl]-7-methoxy-4-methylcoumarin (AMMC) as a specific CYP2D6 probe in human liver microsomes

Prosubstrates of CYP3A4, the Major Human Hepatic Cytochrome P450 : Transformation into Substrates by Other p450 Isoforms

Cytochrome P450 fluorometric substrates: identification of isoform-selective probes for rat CYP2D2 and human CYP3A4

A High-Throughput Screen to Identify Inhibitors of Aromatase (CYP19)

Influence of β-Naphthoflavone and Methoxychlor Pretreatment on the Biotransformation and Estrogenic Activity of Methoxychlor in Channel Catfish (Ictalurus punctatus)

Indole-3-carbinol induces a rat liver glutathione transferase subunit (Yc2) with high activity toward aflatoxin B1 exo-epoxide. Association with reduced levels of hepatic aflatoxin-DNA adducts in vivo

Tissue-specific expression of flavin-containing monooxygenase (FMO) forms 1 and 2 in the rabbit

Biotransformation and estrogenic activity of Methoxychlor and its metabolites in channel catfish ( Ictalurus punctatus)

Fluorometric screening for metabolism-based drug–drug interactions

Selective Time- and NADPH-Dependent Inhibition of Human CYP2E1 by Clomethiazole

Catalytic Characteristics of CYP3A4: Requirement for a Phenolic Function in ortho Hydroxylation of Estradiol and Mono-O-demethylated Methoxychlor

Design and application of fluorometric assays for human cytochrome P450 inhibition

HIGHLY SELECTIVE INHIBITION OF HUMAN CYP3A IN VITRO BY AZAMULIN AND EVIDENCE THAT INHIBITION IS IRREVERSIBLE

Fluorometric High-Throughput Screening for Inhibitors of Cytochrome P450

Ring hydroxylation of [o-3H]methoxychlor as a probe for liver microsomal CYP2B activity: potential for in vivo CYP2B assay

Human cytochrome p450 induction and inhibition potential of clevidipine and its primary metabolite h152/81

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