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Why Does Somatic Hypermutation by AID Require Transcription of Its Target Genes?

Advances in Immunology, 2014, Vol.122, p.253-277

Storb, Ursula

2014

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AID in somatic hypermutation and class switch recombination

Current opinion in immunology, 2006-04, Vol.18 (2), p.164-174

2006

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Activation-Induced Cytidine Deaminase (AID) Can Target Both DNA Strands When the DNA Is Supercoiled

Proceedings of the National Academy of Sciences - PNAS, 2004-08, Vol.101 (35), p.12997-13002

2004

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Somatic Hypermutation and Class Switch Recombination in Msh6-/-Ung-/- Double-Knockout Mice

The Journal of immunology (1950), 2006-10, Vol.177 (8), p.5386-5392

2006

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Somatic Hypermutation of Immunoglobulin Genes Is Linked to Transcription Initiation

Immunity (Cambridge, Mass.), 1996-01, Vol.4 (1), p.57-65

1996

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Nucleosome Stability Dramatically Impacts the Targeting of Somatic Hypermutation

Molecular and Cellular Biology, 2012-05, Vol.32 (10), p.2030-2040

2012

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Somatic hypermutation: Processivity of the cytosine deaminase AID and error-free repair of the resulting uracils

Cell cycle (Georgetown, Tex.), 2009-10, Vol.8 (19), p.3097-3101

2009

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Targeting of the Activation-Induced Cytosine Deaminase Is Strongly Influenced by the Sequence and Structure of the Targeted DNA

Molecular and Cellular Biology, 2005-12, Vol.25 (24), p.10815-10821

2005

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The activation-induced cytidine deaminase (AID) efficiently targets DNA in nucleosomes but only during transcription

The Journal of experimental medicine, 2009-05, Vol.206 (5), p.1057-1071

2009

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The E Box Motif CAGGTG Enhances Somatic Hypermutation without Enhancing Transcription

Immunity (Cambridge, Mass.), 2003-08, Vol.19 (2), p.235-242

2003

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Why Does Somatic Hypermutation by AID Require Transcription of Its Target Genes?: Chapter Seven

Advances in immunology, 2014-01, Vol.122, p.253

Storb, Ursula

2014

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Chapter Seven - Why Does Somatic Hypermutation by AID Require Transcription of Its Target Genes?

Advances in immunology, 2014-01, Vol.122, p.253-277

Storb, Ursula

2014

Volltextzugriff (PDF)

Progress in understanding the mechanism and consequences of somatic hypermutation

Immunological reviews, 1998-04, Vol.162 (1), p.5-11

Storb, Ursula

1998

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DNA Methylation Precedes Chromatin Modifications under the Influence of the Strain-Specific Modifier Ssm1

Molecular and Cellular Biology, 2005-06, Vol.25 (11), p.4782-4791

2005

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The contested role of uracil DNA glycosylase in immunoglobulin gene diversification

Trends in genetics, 2005-05, Vol.21 (5), p.253-256

2005

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Changes in RNA polymerase II progression influence somatic hypermutation of Ig-related genes by AID

The Journal of experimental medicine, 2013-07, Vol.210 (7), p.1481-1492

2013

Volltextzugriff (PDF)

Somatic hypermutation of immunoglobulin and non-immunoglobulin genes

Philosophical transactions of the Royal Society of London. Series B. Biological sciences, 2001-01, Vol.356 (1405), p.13

2001

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Insertion of Phosphoglycerine Kinase (Pgk)-Neo 5′ of Jλ1 Dramatically Enhances Vjλ1 Rearrangement

The Journal of experimental medicine, 2001-03, Vol.193 (6), p.699-712

2001

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Attracting AID to targets of somatic hypermutation

The Journal of experimental medicine, 2010-02, Vol.207 (2), p.405-415

2010

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Ssm1b expression and function in germ cells of adult mice and in early embryos

Molecular reproduction and development, 2017-07, Vol.84 (7), p.596-613

2017

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Identification of Ssm1b, a novel modifier of DNA methylation, and its expression during mouse embryogenesis

Development (Cambridge), 2014-05, Vol.141 (10), p.2024-2034

2014

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A hypermutable insert in an immunoglobulin transgene contains hotspots of somatic mutation and sequences predicting highly stable structures in the RNA transcript

The Journal of experimental medicine, 1998-08, Vol.188 (4), p.689-698

1998

Volltextzugriff (PDF)

Immunoglobulin Genes: Generating Diversity with AID and UNG

Current biology, 2002-10, Vol.12 (21), p.R725-R727

2002

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Ig gene somatic hypermutation in mice defective for DNA polymerase δ proofreading

International immunology, 2003-04, Vol.15 (4), p.477-481

2003

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Mutation of BCL-6 Gene in Normal B Cells by the Process of Somatic Hypermutation of Ig Genes

Science (American Association for the Advancement of Science), 1998-06, Vol.280 (5370), p.1750-1752

1998

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Why Does Somatic Hypermutation by AID Require Transcription of Its Target Genes?

AID in somatic hypermutation and class switch recombination

Activation-Induced Cytidine Deaminase (AID) Can Target Both DNA Strands When the DNA Is Supercoiled

Somatic Hypermutation and Class Switch Recombination in Msh6-/-Ung-/- Double-Knockout Mice

Somatic Hypermutation of Immunoglobulin Genes Is Linked to Transcription Initiation

Nucleosome Stability Dramatically Impacts the Targeting of Somatic Hypermutation

Somatic hypermutation: Processivity of the cytosine deaminase AID and error-free repair of the resulting uracils

Targeting of the Activation-Induced Cytosine Deaminase Is Strongly Influenced by the Sequence and Structure of the Targeted DNA

The activation-induced cytidine deaminase (AID) efficiently targets DNA in nucleosomes but only during transcription

The E Box Motif CAGGTG Enhances Somatic Hypermutation without Enhancing Transcription

Why Does Somatic Hypermutation by AID Require Transcription of Its Target Genes?: Chapter Seven

Chapter Seven - Why Does Somatic Hypermutation by AID Require Transcription of Its Target Genes?

Progress in understanding the mechanism and consequences of somatic hypermutation

DNA Methylation Precedes Chromatin Modifications under the Influence of the Strain-Specific Modifier Ssm1

The contested role of uracil DNA glycosylase in immunoglobulin gene diversification

Changes in RNA polymerase II progression influence somatic hypermutation of Ig-related genes by AID

Somatic hypermutation of immunoglobulin and non-immunoglobulin genes

Insertion of Phosphoglycerine Kinase (Pgk)-Neo 5′ of Jλ1 Dramatically Enhances Vjλ1 Rearrangement

Attracting AID to targets of somatic hypermutation

Ssm1b expression and function in germ cells of adult mice and in early embryos

Identification of Ssm1b, a novel modifier of DNA methylation, and its expression during mouse embryogenesis

A hypermutable insert in an immunoglobulin transgene contains hotspots of somatic mutation and sequences predicting highly stable structures in the RNA transcript

Immunoglobulin Genes: Generating Diversity with AID and UNG

Ig gene somatic hypermutation in mice defective for DNA polymerase δ proofreading

Mutation of BCL-6 Gene in Normal B Cells by the Process of Somatic Hypermutation of Ig Genes

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