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Direct Regulation of Androgen Receptor Activity by Potent CYP17 Inhibitors in Prostate Cancer Cells

The Journal of biological chemistry, 2012-02, Vol.287 (6), p.3777-3787

2012

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Phosphorothioates and Me: A Lecture About My 35 Years in Oligo-World on My Receipt of the 2023 Lifetime Achievement Award of the Oligonucleotide Therapeutics Society

Nucleic acid therapeutics, 2024-08, Vol.34 (4), p.157-163

Stein, Cy A.

2024

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Oligonucleotides to the (Gene) Rescue: FDA Approvals 2017–2019

Trends in pharmacological sciences (Regular ed.), 2020-01, Vol.41 (1), p.27-41

2020

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A Multifunctional LNA Oligonucleotide-Based Strategy Blocks AR Expression and Transactivation Activity in PCa Cells

Molecular therapy. Nucleic acids, 2021-03, Vol.23, p.63-75

2021

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Antisense oligonucleotides in cancer

Current opinion in oncology, 2014-11, Vol.26 (6), p.584-589

2014

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Antisense 2′-Deoxy, 2′-Fluoroarabino Nucleic Acid (2′F-ANA) Oligonucleotides: In Vitro Gymnotic Silencers of Gene Expression Whose Potency Is Enhanced by Fatty Acids

Molecular therapy. Nucleic acids, 2012, Vol.1 (10), p.e43-e43, Article e43

2012

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Ammonium and arsenic trioxide are potent facilitators of oligonucleotide function when delivered by gymnosis

Nucleic acids research, 2018-04, Vol.46 (7), p.3612-3624

2018

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Eteplirsen Approved for Duchenne Muscular Dystrophy: The FDA Faces a Difficult Choice

Molecular therapy, 2016-11, Vol.24 (11), p.1884-1885

Stein, Cy A

2016

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Targeting angiopoietin-2 signaling in cancer therapy

Expert opinion on investigational drugs, 2013-07, Vol.22 (7), p.813-825

2013

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Treatment Sequencing in Metastatic Castration-Resistant Prostate Cancer: A Clinical Commentary

Clinical genitourinary cancer, 2015-10, Vol.13 (5), p.407-409

Stein, Cy A

2015

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Protein Kinase C-α is a Critical Protein for Antisense Oligonucleotide-mediated Silencing in Mammalian Cells

Molecular therapy, 2016-06, Vol.24 (6), p.1117-1125

2016

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Randomized phase 2 therapeutic equivalence study of abiraterone acetate fine particle formulation vs. originator abiraterone acetate in patients with metastatic castration-resistant prostate cancer: The STAAR study

Urologic oncology, 2018-02, Vol.36 (2), p.81.e9-81.e16

2018

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Impact of an alternative steroid on the relative bioavailability and bioequivalence of a novel versus the originator formulation of abiraterone acetate

Cancer chemotherapy and pharmacology, 2017-09, Vol.80 (3), p.479-486

2017

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LDH correlation with survival in advanced melanoma from two large, randomised trials (Oblimersen GM301 and EORTC 18951)

European journal of cancer (1990), 2009-07, Vol.45 (10), p.1807-1814

2009

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Therapeutic Oligonucleotides: The Road Not Taken

Clinical cancer research, 2011-10, Vol.17 (20), p.6369-6372

2011

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Relative Bcl-2 Independence of Drug-Induced Cytotoxicity and Resistance in 518A2 Melanoma Cells

Clinical cancer research, 2004-12, Vol.10 (24), p.8371-8379

2004

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Enzalutamide for the treatment of prostate cancer

Expert opinion on pharmacotherapy, 2013-04, Vol.14 (5), p.679-685

2013

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FDA-Approved Oligonucleotide Therapies in 2017

Molecular therapy, 2017-05, Vol.25 (5), p.1069-1075

2017

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Preoperative therapy for localized prostate cancer: A comprehensive overview

Maturitas, 2013-01, Vol.74 (1), p.3-9

2013

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Prolonged Therapy With Cabazitaxel in an Octogenarian With Metastatic Castration-Resistant Prostate Cancer

Clinical genitourinary cancer, 2012-12, Vol.10 (4), p.274-276

2012

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Inhibition of heparanase activity and tumor metastasis by laminarin sulfate and synthetic phosphorothioate oligodeoxynucleotides

International journal of cancer, 1999-10, Vol.83 (3), p.424-431

1999

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Eteplirsen Approved for Duchenne Muscular Dystrophy: The FDA Faces a Difficult Choice

Molecular therapy, 2016-11, Vol.24 (11), p.1884

Stein, Cy A

2016

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Paclitaxel-Based High-Dose Chemotherapy with Autologous Stem Cell Rescue for Relapsed Germ Cell Tumor: Clinical Outcome and Quality of Life in Long-Term Survivors

Clinical genitourinary cancer, 2013-06, Vol.11 (2), p.121-127

2013

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Comparison of D-G3139 and Its Enantiomer L-G3139 in Melanoma Cells Demonstrates Minimal In Vitro but Dramatic In Vivo Chiral Dependency

Molecular therapy, 2007-02, Vol.15 (2), p.270-278

2007

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Highly loaded nanoparticulate carrier using an hydrophobic antisense oligonucleotide complex

European journal of pharmaceutical sciences, 1999-12, Vol.9 (2), p.163-170

1999

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Direct Regulation of Androgen Receptor Activity by Potent CYP17 Inhibitors in Prostate Cancer Cells

Phosphorothioates and Me: A Lecture About My 35 Years in Oligo-World on My Receipt of the 2023 Lifetime Achievement Award of the Oligonucleotide Therapeutics Society

Oligonucleotides to the (Gene) Rescue: FDA Approvals 2017–2019

A Multifunctional LNA Oligonucleotide-Based Strategy Blocks AR Expression and Transactivation Activity in PCa Cells

Antisense oligonucleotides in cancer

Antisense 2′-Deoxy, 2′-Fluoroarabino Nucleic Acid (2′F-ANA) Oligonucleotides: In Vitro Gymnotic Silencers of Gene Expression Whose Potency Is Enhanced by Fatty Acids

Ammonium and arsenic trioxide are potent facilitators of oligonucleotide function when delivered by gymnosis

Eteplirsen Approved for Duchenne Muscular Dystrophy: The FDA Faces a Difficult Choice

Targeting angiopoietin-2 signaling in cancer therapy

Treatment Sequencing in Metastatic Castration-Resistant Prostate Cancer: A Clinical Commentary

Protein Kinase C-α is a Critical Protein for Antisense Oligonucleotide-mediated Silencing in Mammalian Cells

Randomized phase 2 therapeutic equivalence study of abiraterone acetate fine particle formulation vs. originator abiraterone acetate in patients with metastatic castration-resistant prostate cancer: The STAAR study

Impact of an alternative steroid on the relative bioavailability and bioequivalence of a novel versus the originator formulation of abiraterone acetate

LDH correlation with survival in advanced melanoma from two large, randomised trials (Oblimersen GM301 and EORTC 18951)

Therapeutic Oligonucleotides: The Road Not Taken

Relative Bcl-2 Independence of Drug-Induced Cytotoxicity and Resistance in 518A2 Melanoma Cells

Enzalutamide for the treatment of prostate cancer

FDA-Approved Oligonucleotide Therapies in 2017

Preoperative therapy for localized prostate cancer: A comprehensive overview

Prolonged Therapy With Cabazitaxel in an Octogenarian With Metastatic Castration-Resistant Prostate Cancer

Inhibition of heparanase activity and tumor metastasis by laminarin sulfate and synthetic phosphorothioate oligodeoxynucleotides

Eteplirsen Approved for Duchenne Muscular Dystrophy: The FDA Faces a Difficult Choice

Paclitaxel-Based High-Dose Chemotherapy with Autologous Stem Cell Rescue for Relapsed Germ Cell Tumor: Clinical Outcome and Quality of Life in Long-Term Survivors

Comparison of D-G3139 and Its Enantiomer L-G3139 in Melanoma Cells Demonstrates Minimal In Vitro but Dramatic In Vivo Chiral Dependency

Highly loaded nanoparticulate carrier using an hydrophobic antisense oligonucleotide complex

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