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Cell elasticity is regulated by the tropomyosin isoform composition of the actin cytoskeleton

PloS one, 2015-05, Vol.10 (5), p.e0126214-e0126214

2015

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MAPKAP Kinase-2 phosphorylation of PABPC1 controls its interaction with 14-3-3 proteins after DNA damage: A combined kinase and protein array approach

Frontiers in molecular biosciences, 2023-04, Vol.10, p.1148933

2023

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New approaches to targeting the actin cytoskeleton for chemotherapy

Future medicinal chemistry, 2009-10, Vol.1 (7), p.1311-1331

2009

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Cytoplasmic Localization of Tristetraprolin Involves 14-3-3-dependent and -independent Mechanisms

The Journal of biological chemistry, 2002-05, Vol.277 (20), p.18029-18036

2002

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A Novel Class of Anticancer Compounds Targets the Actin Cytoskeleton in Tumor Cells

Cancer research (Chicago, Ill.), 2013-08, Vol.73 (16), p.5169-5182

2013

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Tumor suppressor tropomyosin Tpm2.1 regulates sensitivity to apoptosis beyond anoikis characterized by changes in the levels of intrinsic apoptosis proteins

Cytoskeleton (Hoboken, N.J.), 2017-06, Vol.74 (6), p.233-248

2017

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Identification of Cancer-Targeted Tropomyosin Inhibitors and Their Synergy with Microtubule Drugs

Molecular cancer therapeutics, 2017-08, Vol.16 (8), p.1555-1565

2017

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Regulation of cell proliferation by ERK and signal-dependent nuclear translocation of ERK is dependent on Tm5NM1-containing actin filaments

Molecular biology of the cell, 2015-07, Vol.26 (13), p.2475-2490

2015

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Small molecule targeting of the actin associating protein tropomyosin Tpm3.1 increases neuroblastoma cell response to inhibition of Rac‐mediated multicellular invasion

Cytoskeleton (Hoboken, N.J.), 2018-07, Vol.75 (7), p.307-317

2018

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A small molecule inhibitor of tropomyosin dissociates actin binding from tropomyosin-directed regulation of actin dynamics

Scientific reports, 2016-01, Vol.6 (1), p.19816-19816, Article 19816

2016

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On-target action of anti-tropomyosin drugs regulates glucose metabolism

Scientific reports, 2018-03, Vol.8 (1), p.4604-13, Article 4604

2018

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Cover Image, Volume 74, Issue 6

Cytoskeleton (Hoboken, N.J.), 2017-06, Vol.74 (6), p.C4

2017

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Cover Image, Volume 74, Issue 6

Cytoskeleton (Hoboken, N.J.), 2017-06, Vol.74 (6), p.C1

2017

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Hypoxia alters the recruitment of tropomyosins into the actin stress fibres of neuroblastoma cells

BMC cancer, 2015-10, Vol.15 (1), p.712-712, Article 712

2015

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The actin cytoskeleton as a sensor and mediator of apoptosis

Bioarchitecture, 2012-05, Vol.2 (3), p.75-87

2012

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High-Content Imaging of Unbiased Chemical Perturbations Reveals that the Phenotypic Plasticity of the Actin Cytoskeleton Is Constrained

Cell systems, 2019-11, Vol.9 (5), p.496-507.e5

2019

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Specialisation of the tropomyosin composition of actin filaments provides new potential targets for chemotherapy

Current cancer drug targets, 2006-05, Vol.6 (3), p.245-256

2006

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Phosphorylation of nonmuscle myosin heavy chain IIA on Ser1917 is mediated by protein kinase C beta II and coincides with the onset of stimulated degranulation of RBL-2H3 mast cells

The Journal of immunology (1950), 2006-08, Vol.177 (3), p.1492-1499

2006

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Abstract C208: Targeting the actin cytoskeleton of neuroblastoma: Elucidating the mechanism by which a novel class of anti-cancer compounds induces tumor cell death

Molecular cancer therapeutics, 2013-11, Vol.12 (11_Supplement), p.C208-C208

2013

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Abstract B50: Synergistic anti-neuroblastoma efficacy using combinatorial cytoskeletal inhibitors

Cancer research (Chicago, Ill.), 2014-10, Vol.74 (20_Supplement), p.B50-B50

2014

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Abstract 1827: Developing chemotherapeutics which selectively disable the actin cytoskeleton of tumor cells

Cancer research (Chicago, Ill.), 2012-04, Vol.72 (8_Supplement), p.1827-1827

2012

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Abstract 5230: Improving the specificity of drugs which target the actin cytoskeleton for cancer therapy

Cancer research (Chicago, Ill.), 2012-04, Vol.72 (8_Supplement), p.5230-5230

2012

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Abstract A178: Developing chemotherapeutics which selectively disable the actin cytoskeleton of tumor cells

Molecular cancer therapeutics, 2011-11, Vol.10 (11_Supplement), p.A178-A178

2011

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Phosphorylation of Nonmuscle Myosin Heavy Chain IIA on Ser super(1917) Is Mediated by Protein Kinase C beta II and Coincides with the Onset of Stimulated Degranulation of RBL-2H3 Mast Cells

Journal of Immunology, 2006-08, Vol.177 (3), p.1492-1499

2006

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Phosphorylation of Nonmuscle Myosin Heavy Chain IIA on Ser1917 Is Mediated by Protein Kinase CbetaII and Coincides with the Onset of Stimulated Degranulation of RBL-2H3 Mast Cells

The Journal of immunology (1950), 2006-08, Vol.177 (3), p.1492

2006

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Cell elasticity is regulated by the tropomyosin isoform composition of the actin cytoskeleton

MAPKAP Kinase-2 phosphorylation of PABPC1 controls its interaction with 14-3-3 proteins after DNA damage: A combined kinase and protein array approach

New approaches to targeting the actin cytoskeleton for chemotherapy

Cytoplasmic Localization of Tristetraprolin Involves 14-3-3-dependent and -independent Mechanisms

A Novel Class of Anticancer Compounds Targets the Actin Cytoskeleton in Tumor Cells

Tumor suppressor tropomyosin Tpm2.1 regulates sensitivity to apoptosis beyond anoikis characterized by changes in the levels of intrinsic apoptosis proteins

Identification of Cancer-Targeted Tropomyosin Inhibitors and Their Synergy with Microtubule Drugs

Regulation of cell proliferation by ERK and signal-dependent nuclear translocation of ERK is dependent on Tm5NM1-containing actin filaments

Small molecule targeting of the actin associating protein tropomyosin Tpm3.1 increases neuroblastoma cell response to inhibition of Rac‐mediated multicellular invasion

A small molecule inhibitor of tropomyosin dissociates actin binding from tropomyosin-directed regulation of actin dynamics

On-target action of anti-tropomyosin drugs regulates glucose metabolism

Cover Image, Volume 74, Issue 6

Cover Image, Volume 74, Issue 6

Hypoxia alters the recruitment of tropomyosins into the actin stress fibres of neuroblastoma cells

The actin cytoskeleton as a sensor and mediator of apoptosis

High-Content Imaging of Unbiased Chemical Perturbations Reveals that the Phenotypic Plasticity of the Actin Cytoskeleton Is Constrained

Specialisation of the tropomyosin composition of actin filaments provides new potential targets for chemotherapy

Phosphorylation of nonmuscle myosin heavy chain IIA on Ser1917 is mediated by protein kinase C beta II and coincides with the onset of stimulated degranulation of RBL-2H3 mast cells

Abstract C208: Targeting the actin cytoskeleton of neuroblastoma: Elucidating the mechanism by which a novel class of anti-cancer compounds induces tumor cell death

Abstract B50: Synergistic anti-neuroblastoma efficacy using combinatorial cytoskeletal inhibitors

Abstract 1827: Developing chemotherapeutics which selectively disable the actin cytoskeleton of tumor cells

Abstract 5230: Improving the specificity of drugs which target the actin cytoskeleton for cancer therapy

Abstract A178: Developing chemotherapeutics which selectively disable the actin cytoskeleton of tumor cells

Phosphorylation of Nonmuscle Myosin Heavy Chain IIA on Ser super(1917) Is Mediated by Protein Kinase C beta II and Coincides with the Onset of Stimulated Degranulation of RBL-2H3 Mast Cells

Phosphorylation of Nonmuscle Myosin Heavy Chain IIA on Ser1917 Is Mediated by Protein Kinase CbetaII and Coincides with the Onset of Stimulated Degranulation of RBL-2H3 Mast Cells

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