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Resistance to ddI and Sensitivity to AZT Induced by a Mutation in HIV-1 Reverse Transcriptase

Science (American Association for the Advancement of Science), 1991-09, Vol.253 (5027), p.1557-1559

1991

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1592U89, a novel carbocyclic nucleoside analog with potent, selective anti-human immunodeficiency virus activity

Antimicrobial Agents and Chemotherapy, 1997-05, Vol.41 (5), p.1082-1093

1997

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Unique intracellular activation of the potent anti-human immunodeficiency virus agent 1592U89

Antimicrobial Agents and Chemotherapy, 1997-05, Vol.41 (5), p.1099-1107

1997

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3'-Azido-3'-deoxythymidine triphosphate as an inhibitor and substrate of purified human immunodeficiency virus reverse transcriptase

Antimicrobial Agents and Chemotherapy, 1987-12, Vol.31 (12), p.1972-1977

1987

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Phosphorylation of 3'-azido-3'-deoxythymidine and selective interaction of the 5'-triphosphate with human immunodeficiency virus reverse transcriptase

Proceedings of the National Academy of Sciences - PNAS, 1986-11, Vol.83 (21), p.8333-8337

1986

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3′-Azido-3′-deoxythymidine (BW A509U): An Antiviral Agent That Inhibits the Infectivity and Cytopathic Effect of Human T-Lymphotropic Virus Type III/Lymphadenopathy-Associated Virus in vitro

Proceedings of the National Academy of Sciences - PNAS, 1985-10, Vol.82 (20), p.7096-7100

1985

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Antiviral, metabolic, and pharmacokinetic properties of the isomeric dideoxynucleoside 4(S)-(6-amino-9H-purin-9-yl)tetrahydro-2(S)-furanmethanol

Antimicrobial Agents and Chemotherapy, 1995-09, Vol.39 (9), p.1993-1999

1995

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5-Chloro-2',3'-dideoxy-3'-fluorouridine (935U83), a selective anti-human immunodeficiency virus agent with an improved metabolic and toxicological profile

Antimicrobial Agents and Chemotherapy, 1994-07, Vol.38 (7), p.1590-1603

1994

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Acyclovir triphosphate is a suicide inactivator of the herpes simplex virus DNA polymerase

The Journal of biological chemistry, 1984-08, Vol.259 (15), p.9575-9579

1984

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Inhibition by ganciclovir of cell growth and DNA synthesis of cells biochemically transformed with herpesvirus genetic information

Antimicrobial Agents and Chemotherapy, 1987-06, Vol.31 (6), p.844-849

1987

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Anti-human immunodeficiency virus synergism by zidovudine (3'-azidothymidine) and didanosine (dideoxyinosine) contrasts with their additive inhibition of normal human marrow progenitor cells

Antimicrobial Agents and Chemotherapy, 1991-02, Vol.35 (2), p.322-328

1991

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Pathogenicity of acyclovir-resistant herpes simplex virus type 1 from an immunodeficient child

The Journal of infectious diseases, 1982-11, Vol.146 (5), p.673-682

1982

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Inhibition of herpes simplex virus-induced DNA polymerase activity and viral DNA replication by 9-(2-hydroxyethoxymethyl)guanine and its triphosphate

Journal of Virology, 1979-10, Vol.32 (1), p.72-77

1979

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Prostate brachytherapy seed migration to the heart seen on cardiovascular computed tomographic angiography

Radiology case reports, 2017-03, Vol.12 (1), p.31-33

2017

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Inhibition of purified human and herpes simplex virus-induced DNA polymerases by 9-(2-hydroxyethoxymethyl)guanine triphosphate. Effects on primer-template function

The Journal of biological chemistry, 1981-11, Vol.256 (22), p.11447-11451

1981

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Potentiation of Antiherpetic Activity of Acyclovir by Ribonucleotide Reductase Inhibition

Proceedings of the National Academy of Sciences - PNAS, 1985-06, Vol.82 (12), p.4254-4257

1985

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Reduced in vivo Mutagenesis by Mutant Herpes Simplex DNA Polymerase Involves Improved Nucleotide Selection

Proceedings of the National Academy of Sciences - PNAS, 1985-06, Vol.82 (11), p.3889-3893

1985

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Inhibition of cellular alpha DNA polymerase and herpes simplex virus-induced DNA polymerases by the triphosphate of BW759U

Antimicrobial Agents and Chemotherapy, 1984-02, Vol.25 (2), p.191-194

1984

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Metabolism of acyclovir in virus-infected and uninfected cells

Antimicrobial Agents and Chemotherapy, 1981-10, Vol.20 (4), p.518-524

1981

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In vitro antiviral activity of 141W94 (VX-478) in combination with other antiretroviral agents

Antiviral research, 1996, Vol.29 (1), p.53-56

1996

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HIV-1 sensitivity to zidovudine and clinical outcome in children

The Lancet (British edition), 1992-01, Vol.339 (8784), p.15-19

1992

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Acyclovir-resistant mutants of herpes simplex virus type 1 express altered DNA polymerase or reduced acyclovir phosphorylating activities

Journal of Virology, 1981-12, Vol.40 (3), p.936-941

1981

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Inhibition of cellular alpha and virally induced deoxyribonucleic acid polymerases by the triphosphate of acyclovir

Antimicrobial Agents and Chemotherapy, 1980-11, Vol.18 (5), p.741-745

1980

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Effects of 3′-azido-3′-deoxythymidine on the deoxynucleotide triphosphate pools of cultured human cells

Biochemical and biophysical research communications, 1988-07, Vol.154 (1), p.124-129

1988

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In-vitro resistance to zidovudine and alpha-interferon in HIV-1 isolates from patients: correlations with treatment duration and response

Annals of internal medicine, 1992-09, Vol.117 (6), p.457-460

1992

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Resistance to ddI and Sensitivity to AZT Induced by a Mutation in HIV-1 Reverse Transcriptase

1592U89, a novel carbocyclic nucleoside analog with potent, selective anti-human immunodeficiency virus activity

Unique intracellular activation of the potent anti-human immunodeficiency virus agent 1592U89

3'-Azido-3'-deoxythymidine triphosphate as an inhibitor and substrate of purified human immunodeficiency virus reverse transcriptase

Phosphorylation of 3'-azido-3'-deoxythymidine and selective interaction of the 5'-triphosphate with human immunodeficiency virus reverse transcriptase

3′-Azido-3′-deoxythymidine (BW A509U): An Antiviral Agent That Inhibits the Infectivity and Cytopathic Effect of Human T-Lymphotropic Virus Type III/Lymphadenopathy-Associated Virus in vitro

Antiviral, metabolic, and pharmacokinetic properties of the isomeric dideoxynucleoside 4(S)-(6-amino-9H-purin-9-yl)tetrahydro-2(S)-furanmethanol

5-Chloro-2',3'-dideoxy-3'-fluorouridine (935U83), a selective anti-human immunodeficiency virus agent with an improved metabolic and toxicological profile

Acyclovir triphosphate is a suicide inactivator of the herpes simplex virus DNA polymerase

Inhibition by ganciclovir of cell growth and DNA synthesis of cells biochemically transformed with herpesvirus genetic information

Anti-human immunodeficiency virus synergism by zidovudine (3'-azidothymidine) and didanosine (dideoxyinosine) contrasts with their additive inhibition of normal human marrow progenitor cells

Pathogenicity of acyclovir-resistant herpes simplex virus type 1 from an immunodeficient child

Inhibition of herpes simplex virus-induced DNA polymerase activity and viral DNA replication by 9-(2-hydroxyethoxymethyl)guanine and its triphosphate

Prostate brachytherapy seed migration to the heart seen on cardiovascular computed tomographic angiography

Inhibition of purified human and herpes simplex virus-induced DNA polymerases by 9-(2-hydroxyethoxymethyl)guanine triphosphate. Effects on primer-template function

Potentiation of Antiherpetic Activity of Acyclovir by Ribonucleotide Reductase Inhibition

Reduced in vivo Mutagenesis by Mutant Herpes Simplex DNA Polymerase Involves Improved Nucleotide Selection

Inhibition of cellular alpha DNA polymerase and herpes simplex virus-induced DNA polymerases by the triphosphate of BW759U

Metabolism of acyclovir in virus-infected and uninfected cells

In vitro antiviral activity of 141W94 (VX-478) in combination with other antiretroviral agents

HIV-1 sensitivity to zidovudine and clinical outcome in children

Acyclovir-resistant mutants of herpes simplex virus type 1 express altered DNA polymerase or reduced acyclovir phosphorylating activities

Inhibition of cellular alpha and virally induced deoxyribonucleic acid polymerases by the triphosphate of acyclovir

Effects of 3′-azido-3′-deoxythymidine on the deoxynucleotide triphosphate pools of cultured human cells

In-vitro resistance to zidovudine and alpha-interferon in HIV-1 isolates from patients: correlations with treatment duration and response

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