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Development of Orally Active Nonpeptidic Inhibitors of Human Neutrophil Elastase

Journal of medicinal chemistry, 2001-04, Vol.44 (8), p.1268-1285

2001

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Design and Synthesis of New Orally Active Nonpeptidic Inhibitors of Human Neutrophil Elastase

Journal of medicinal chemistry, 2000-12, Vol.43 (26), p.4927-4929

2000

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Biologically Active Heteroarotinoids Exhibiting Anticancer Activity and Decreased Toxicity

Journal of medicinal chemistry, 1997-10, Vol.40 (22), p.3567-3583

1997

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Bradykinin antagonists in human systems: Correlation between receptor binding, calcium signalling in isolated cells, and functional activity in isolated ileum

Biochemical pharmacology, 1997-07, Vol.54 (2), p.283-291

1997

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Novel heteroarotinoids: synthesis and biological activity

Journal of medicinal chemistry, 1991-01, Vol.34 (1), p.430-439

1991

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Heteroarotinoids. Synthesis, characterization, and biological activity in terms of an assessment of these systems to inhibit the induction of ornithine decarboxylase activity and to induce terminal differentiation of HL-60 cells

Journal of medicinal chemistry, 1987-08, Vol.30 (8), p.1474-1482

1987

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Structure of methyl (E)-p-[3,3,3-trifluoro-2-(2,2,4,4-tetramethyl-6-thiochromanyl)-1-propenyl]benzoate

Acta crystallographica. Section C, Crystal structure communications, 1989-05, Vol.45 (5), p.750-754

1989

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New ditopic receptors for alkylammonium ion complexation

Journal of Inclusion Phenomena and Molecular Recognition in Chemistry, 1993-06, Vol.15 (2), p.181-193

1993

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Synthesis and evaluation of CE-0266: A new human neutrophil elastase inhibitor

Bioorganic chemistry, 1992-12, Vol.20 (4), p.345-355

1992

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The structure of methyl 2-chloro-8-oxo-6H,8H-[1]benzopyrano[4',3':4,5]imidazo[2,1-b][1,3]thiazine-10-carboxylate

Acta crystallographica. Section C, Crystal structure communications, 1987-09, Vol.43 (9), p.1723-1726

1987

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Biochemical Characterization of α-Ketooxadiazole Inhibitors of Elastases

Archives of biochemistry and biophysics, 1999-07, Vol.367 (2), p.193-201

1999

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STEREOCHEMICAL AND A SINGLE-CRYSTAL X-RAY DIFFRACTION ANALYSIS OF 2,3,4,4a,6,10b-HEXAHYDRO-6-PHENYL-1,4-METHANO-1H-DIBENZO[b,d]THIOPYRAN: THE ADDITION PRODUCT FROM THE REACTION OF DIPHENYL THIONE AND NORBORNENE

Phosphorus and sulfur and the related elements, 1985-05, Vol.22 (3), p.337-348

1985

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Heteroarotinoids: analytical criteria for the rapid identification of E and Z isomers of these novel retinoids via NMR, UV, and x-ray analyses of selected examples

Journal of organic chemistry, 1990-06, Vol.55 (13), p.3984-3991

1990

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Synthesis and characterization of human neutrophil elastase inhibitors derived from aromatic esters of phenylalkanoic acids

Agents and actions. Supplements, 1993, Vol.42, p.71

1993

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ChemInform Abstract: Novel Heteroarotinoids: Synthesis and Biological Activity

ChemInform, 1991-06, Vol.22 (24), p.no-no

1991

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Sustained release of endothelial progenitor cell-derived extracellular vesicles from shear-thinning hydrogels improves angiogenesis and promotes function after myocardial infarction

Cardiovascular research, 2018-06, Vol.114 (7), p.1029-1040

2018

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Measuring novice-expert sense of place for a far-away place: Implications for geoscience instruction

PloS one, 2023-10, Vol.18 (10), p.e0293003-e0293003

2023

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Precise interpolar phasing of abrupt climate change during the last ice age

Nature (London), 2015-04, Vol.520 (7549), p.661-665

2015

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HELLS and PRDM9 form a pioneer complex to open chromatin at meiotic recombination hot spots

Genes & development, 2020-03, Vol.34 (5-6), p.398-412

2020

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The proinflammatory mediators C3a and C5a are essential for liver regeneration

The Journal of experimental medicine, 2003-09, Vol.198 (6), p.913-923

2003

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Factors Associated With Recurrent Pediatric Firearm Injury : A 10-Year Retrospective Cohort Analysis

Annals of internal medicine, 2024-10, Vol.177 (10), p.1381-1388

2024

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Pharmacokinetics of Tranexamic Acid Given as an Intramuscular Injection Compared to Intravenous Infusion in a Swine Model of Ongoing Hemorrhage

Shock (Augusta, Ga.), 2020-06, Vol.53 (6), p.754-760

2020

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Early sedation with dexmedetomidine in ventilated critically ill patients and heterogeneity of treatment effect in the SPICE III randomised controlled trial

Intensive care medicine, 2021-04, Vol.47 (4), p.455-466

2021

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Automated Partial Versus Complete Resuscitative Endovascular Balloon Occlusion of the Aorta for the Management of Hemorrhagic Shock in a Pig Model of Polytrauma: a Randomized Controlled Pilot Study

Military medicine, 2020-12, Vol.185 (11-12), p.e1923-e1930

2020

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Genetic Variants Associated with Lp(a) Lipoprotein Level and Coronary Disease

The New England journal of medicine, 2009-12, Vol.361 (26), p.2518-2528

2009

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Development of Orally Active Nonpeptidic Inhibitors of Human Neutrophil Elastase

Design and Synthesis of New Orally Active Nonpeptidic Inhibitors of Human Neutrophil Elastase

Biologically Active Heteroarotinoids Exhibiting Anticancer Activity and Decreased Toxicity

Bradykinin antagonists in human systems: Correlation between receptor binding, calcium signalling in isolated cells, and functional activity in isolated ileum

Novel heteroarotinoids: synthesis and biological activity

Heteroarotinoids. Synthesis, characterization, and biological activity in terms of an assessment of these systems to inhibit the induction of ornithine decarboxylase activity and to induce terminal differentiation of HL-60 cells

Structure of methyl (E)-p-[3,3,3-trifluoro-2-(2,2,4,4-tetramethyl-6-thiochromanyl)-1-propenyl]benzoate

New ditopic receptors for alkylammonium ion complexation

Synthesis and evaluation of CE-0266: A new human neutrophil elastase inhibitor

The structure of methyl 2-chloro-8-oxo-6H,8H-[1]benzopyrano[4',3':4,5]imidazo[2,1-b][1,3]thiazine-10-carboxylate

Biochemical Characterization of α-Ketooxadiazole Inhibitors of Elastases

STEREOCHEMICAL AND A SINGLE-CRYSTAL X-RAY DIFFRACTION ANALYSIS OF 2,3,4,4a,6,10b-HEXAHYDRO-6-PHENYL-1,4-METHANO-1H-DIBENZO[b,d]THIOPYRAN: THE ADDITION PRODUCT FROM THE REACTION OF DIPHENYL THIONE AND NORBORNENE

Heteroarotinoids: analytical criteria for the rapid identification of E and Z isomers of these novel retinoids via NMR, UV, and x-ray analyses of selected examples

Synthesis and characterization of human neutrophil elastase inhibitors derived from aromatic esters of phenylalkanoic acids

ChemInform Abstract: Novel Heteroarotinoids: Synthesis and Biological Activity

Sustained release of endothelial progenitor cell-derived extracellular vesicles from shear-thinning hydrogels improves angiogenesis and promotes function after myocardial infarction

Measuring novice-expert sense of place for a far-away place: Implications for geoscience instruction

Precise interpolar phasing of abrupt climate change during the last ice age

HELLS and PRDM9 form a pioneer complex to open chromatin at meiotic recombination hot spots

The proinflammatory mediators C3a and C5a are essential for liver regeneration

Factors Associated With Recurrent Pediatric Firearm Injury : A 10-Year Retrospective Cohort Analysis

Pharmacokinetics of Tranexamic Acid Given as an Intramuscular Injection Compared to Intravenous Infusion in a Swine Model of Ongoing Hemorrhage

Early sedation with dexmedetomidine in ventilated critically ill patients and heterogeneity of treatment effect in the SPICE III randomised controlled trial

Automated Partial Versus Complete Resuscitative Endovascular Balloon Occlusion of the Aorta for the Management of Hemorrhagic Shock in a Pig Model of Polytrauma: a Randomized Controlled Pilot Study

Genetic Variants Associated with Lp(a) Lipoprotein Level and Coronary Disease

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