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Detection of levodopa, dopamine and its metabolites in rat striatum dialysates following peripheral administration of l-DOPA prodrugs by mean of HPLC–EC

Journal of pharmaceutical and biomedical analysis, 2005-01, Vol.36 (5), p.1079-1084

2005

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Ibuprofen and lipoic acid codrug 1 control Alzheimer's disease progression by down-regulating protein kinase C ε-mediated metalloproteinase 2 and 9 levels in β-amyloid infused Alzheimer's disease rat model

Brain research, 2011-09, Vol.1412, p.79-87

2011

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Biodegradable Microspheres Loaded with an Anti-Parkinson Prodrug: An in Vivo Pharmacokinetic Study

Molecular pharmaceutics, 2011-12, Vol.8 (6), p.2408-2415

2011

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Preparation and characterization of poly(lactic-co-glycolic acid) microspheres loaded with a labile antiparkinson prodrug

International journal of pharmaceutics, 2011-05, Vol.409 (1), p.289-296

2011

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Novel O-palmitoylscleroglucan-coated liposomes as drug carriers: Development, characterization and interaction with leuprolide

International journal of pharmaceutics, 2006-11, Vol.325 (1), p.155-162

2006

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Ibuprofen and Lipoic Acid Diamide as Co-Drug with Neuroprotective Activity: Pharmacological Properties and Effects in β-Amyloid (1–40) Infused Alzheimer's Disease Rat Model

International journal of immunopathology and pharmacology, 2010-04, Vol.23 (2), p.589-599

2010

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Glycosyl and polyalcoholic prodrugs of lonidamine

Bioorganic & medicinal chemistry, 2008-04, Vol.18 (7), p.2445-2450

2008

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Potential antibacterial activity of carvacrol-loaded poly(DL-lactide-co-glycolide) (PLGA) nanoparticles against microbial biofilm

International journal of molecular sciences, 2011-08, Vol.12 (8), p.5039-5051

2011

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Influence of treatment with CDP-choline or choline alphoscerate on brain dopamine and acetylcholine transporters

Journal of the neurological sciences, 2009, Vol.283 (1), p.285-285

2009

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pPKCα-mediated effect on in vitro Aβ production in response to gamma secretase inhibitor LY411575 in rat CTXTNA2 astrocytes

Journal of biological regulators and homeostatic agents, 2012-04, Vol.26 (2), p.245-251

2012

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Potent isozyme-selective inhibition of human glutathione S-transferase A1-1 by a novel glutathione S-conjugate

Amino acids, 2005-11, Vol.29 (3), p.255-261

2005

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Transdermal donepezil on the treatment of Alzheimer's disease

Neuropsychiatric disease and treatment, 2012-01, Vol.8, p.361-368

2012

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Synthesis and Preliminary Evaluation of L-Dopa/Benserazide Conjugates as Dual Acting Codrugs

Letters in drug design & discovery, 2006-12, Vol.3 (10), p.747-752

2006

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Designing prodrugs for the treatment of Parkinson's disease

Expert opinion on drug discovery, 2012-05, Vol.7 (5), p.385-406

2012

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Synthesis and Study of l-Dopa−Glutathione Codrugs as New Anti-Parkinson Agents with Free Radical Scavenging Properties

Journal of medicinal chemistry, 2007-05, Vol.50 (10), p.2506-2515

2007

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Transition state isosteres of the γ-glutamyl peptide bond hydrolysis: synthesis and characterization of the ψ[CH2NH] pseudopeptide analogue of glutathione

Journal of peptide science, 2004-02, Vol.10 (2), p.109-114

2004

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L-Dopa− and Dopamine−(R)-α-Lipoic Acid Conjugates as Multifunctional Codrugs with Antioxidant Properties

Journal of medicinal chemistry, 2006-02, Vol.49 (4), p.1486-1493

2006

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Evaluation of 2,3,4,8,13a Hexahydro-1H-Benzo[5,6]Cyclohepta-6,7- Dihydroxy[1,2,3-ef][3]Benzazepine Derivatives as Dopamine Receptor Ligands

Letters in drug design & discovery, 2006-02, Vol.3 (1), p.55-60

2006

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Ibuprofen-Glutathione Conjugate as Anti-inflammatory and Anti-apoptotic Agent in Rat Brain Infused with β Amyloid (1-40)

Journal of cytology & histology, 2012, Vol.5 (4)

Sozio P, De Colli M

2012

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Ibuprofen and lipoic acid codrug 1 control Alzheimer's disease progression by down-regulating protein kinase C e-mediated metalloproteinase 2 and 9 levels in β-amyloid infused Alzheimer's disease rat model

Brain research, 2011, Vol.1412, p.79-87

2011

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Synthesis and activity of novel glutathione analogues containing an urethane backbone linkage

Farmaco (Società chimica italiana : 1989), 2003-09, Vol.58 (9), p.787-793

2003

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Evaluation of rat striatal l-dopa and DA concentration after intraperitoneal administration of l-dopa prodrugs in liposomal formulations

Journal of controlled release, 2004-09, Vol.99 (2), p.293-300

2004

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Maleic- and fumaric-diamides of (O,O-diacetyl)-L-Dopa-methylester as anti-Parkinson prodrugs in liposomal formulation

Journal of drug targeting, 2006-11, Vol.14 (9), p.652-661

2006

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Synthesis and biological evaluation of a novel pyroglutamyl-modified TRH analogue

Farmaco (Società chimica italiana : 1989), 2002-06, Vol.57 (6), p.479-486

2002

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Dimeric l-Dopa Derivatives as Potential Prodrugs

Bioorganic & medicinal chemistry letters, 2001-04, Vol.11 (8), p.1085-1088

2001

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Detection of levodopa, dopamine and its metabolites in rat striatum dialysates following peripheral administration of l-DOPA prodrugs by mean of HPLC–EC

Ibuprofen and lipoic acid codrug 1 control Alzheimer's disease progression by down-regulating protein kinase C ε-mediated metalloproteinase 2 and 9 levels in β-amyloid infused Alzheimer's disease rat model

Biodegradable Microspheres Loaded with an Anti-Parkinson Prodrug: An in Vivo Pharmacokinetic Study

Preparation and characterization of poly(lactic-co-glycolic acid) microspheres loaded with a labile antiparkinson prodrug

Novel O-palmitoylscleroglucan-coated liposomes as drug carriers: Development, characterization and interaction with leuprolide

Ibuprofen and Lipoic Acid Diamide as Co-Drug with Neuroprotective Activity: Pharmacological Properties and Effects in β-Amyloid (1–40) Infused Alzheimer's Disease Rat Model

Glycosyl and polyalcoholic prodrugs of lonidamine

Potential antibacterial activity of carvacrol-loaded poly(DL-lactide-co-glycolide) (PLGA) nanoparticles against microbial biofilm

Influence of treatment with CDP-choline or choline alphoscerate on brain dopamine and acetylcholine transporters

pPKCα-mediated effect on in vitro Aβ production in response to gamma secretase inhibitor LY411575 in rat CTXTNA2 astrocytes

Potent isozyme-selective inhibition of human glutathione S-transferase A1-1 by a novel glutathione S-conjugate

Transdermal donepezil on the treatment of Alzheimer's disease

Synthesis and Preliminary Evaluation of L-Dopa/Benserazide Conjugates as Dual Acting Codrugs

Designing prodrugs for the treatment of Parkinson's disease

Synthesis and Study of l-Dopa−Glutathione Codrugs as New Anti-Parkinson Agents with Free Radical Scavenging Properties

Transition state isosteres of the γ-glutamyl peptide bond hydrolysis: synthesis and characterization of the ψ[CH2NH] pseudopeptide analogue of glutathione

L-Dopa− and Dopamine−(R)-α-Lipoic Acid Conjugates as Multifunctional Codrugs with Antioxidant Properties

Evaluation of 2,3,4,8,13a Hexahydro-1H-Benzo[5,6]Cyclohepta-6,7- Dihydroxy[1,2,3-ef][3]Benzazepine Derivatives as Dopamine Receptor Ligands

Ibuprofen-Glutathione Conjugate as Anti-inflammatory and Anti-apoptotic Agent in Rat Brain Infused with β Amyloid (1-40)

Ibuprofen and lipoic acid codrug 1 control Alzheimer's disease progression by down-regulating protein kinase C e-mediated metalloproteinase 2 and 9 levels in β-amyloid infused Alzheimer's disease rat model

Synthesis and activity of novel glutathione analogues containing an urethane backbone linkage

Evaluation of rat striatal l-dopa and DA concentration after intraperitoneal administration of l-dopa prodrugs in liposomal formulations

Maleic- and fumaric-diamides of (O,O-diacetyl)-L-Dopa-methylester as anti-Parkinson prodrugs in liposomal formulation

Synthesis and biological evaluation of a novel pyroglutamyl-modified TRH analogue

Dimeric l-Dopa Derivatives as Potential Prodrugs

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