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Clostridium difficile spore biology: sporulation, germination, and spore structural proteins

Trends in microbiology (Regular ed.), 2014-07, Vol.22 (7), p.406-416

2014

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Bile acid-independent protection against Clostridioides difficile infection

PLoS pathogens, 2021-10, Vol.17 (10), p.e1010015-e1010015

2021

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Inhibiting the Initiation of Clostridium difficile Spore Germination using Analogs of Chenodeoxycholic Acid, a Bile Acid

Journal of Bacteriology, 2010-10, Vol.192 (19), p.4983-4990

2010

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Bile acid recognition by the Clostridium difficile germinant receptor, CspC, is important for establishing infection

PLoS pathogens, 2013-05, Vol.9 (5), p.e1003356-e1003356

2013

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Bile Salts and Glycine as Cogerminants for Clostridium difficile Spores

Journal of Bacteriology, 2008-04, Vol.190 (7), p.2505-2512

2008

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The requirement for co-germinants during Clostridium difficile spore germination is influenced by mutations in yabG and cspA

PLoS pathogens, 2019-04, Vol.15 (4), p.e1007681

2019

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Clostridioides difficile Biology: Sporulation, Germination, and Corresponding Therapies for C. difficile Infection

Frontiers in cellular and infection microbiology, 2018-02, Vol.8, p.29-29

2018

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Hierarchical recognition of amino acid co-germinants during Clostridioides difficile spore germination

Anaerobe, 2018-02, Vol.49, p.41-47

2018

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Gut associated metabolites and their roles in Clostridioides difficile pathogenesis

Gut microbes, 2022-12, Vol.14 (1), p.2094672

2022

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Spore Cortex Hydrolysis Precedes Dipicolinic Acid Release during Clostridium difficile Spore Germination

Journal of bacteriology, 2015-07, Vol.197 (14), p.2276-2283

2015

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The small acid-soluble proteins of Clostridioides difficile are important for UV resistance and serve as a check point for sporulation

PLoS pathogens, 2021-09, Vol.17 (9), p.e1009516

2021

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Using CRISPR-Cas9-mediated genome editing to generate C. difficile mutants defective in selenoproteins synthesis

Scientific reports, 2017-11, Vol.7 (1), p.14672-12, Article 14672

2017

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Chenodeoxycholate Is an Inhibitor of Clostridium difficile Spore Germination

Journal of Bacteriology, 2009-02, Vol.191 (3), p.1115-1117

2009

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Metabolism of bile salts in mice influences spore germination in Clostridium difficile

PloS one, 2010-01, Vol.5 (1), p.e8740-e8740

2010

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Muricholic acids inhibit Clostridium difficile spore germination and growth

PloS one, 2013-09, Vol.8 (9), p.e73653-e73653

2013

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Reexamining the Germination Phenotypes of Several Clostridium difficile Strains Suggests Another Role for the CspC Germinant Receptor

Journal of bacteriology, 2016-03, Vol.198 (5), p.777-786

2016

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Microbial Bile Acid Metabolic Clusters: The Bouncers at the Bar

Cell host & microbe, 2014-11, Vol.16 (5), p.551-552

Sorg, Joseph A.

2014

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Clostridioides difficile bile salt hydrolase activity has substrate specificity and affects biofilm formation

NPJ biofilms and microbiomes, 2022-11, Vol.8 (1), p.94-10, Article 94

2022

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Conservation of the "Outside-in" Germination Pathway in Paraclostridium bifermentans

Frontiers in microbiology, 2018-10, Vol.9, p.2487-2487

2018

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Identification of a Novel Lipoprotein Regulator of Clostridium difficile Spore Germination

PLoS pathogens, 2015-10, Vol.11 (10), p.e1005239

2015

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Small molecule inhibitor of lipoteichoic acid synthesis is an antibiotic for Gram-positive bacteria

Proceedings of the National Academy of Sciences - PNAS, 2013-02, Vol.110 (9), p.3531-3536

2013

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A sporulation signature protease is required for assembly of the spore surface layers, germination and host colonization in Clostridioides difficile

PLoS pathogens, 2023-11, Vol.19 (11), p.e1011741-e1011741

2023

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Both Fidaxomicin and Vancomycin Inhibit Outgrowth of Clostridium difficile Spores

Antimicrobial Agents and Chemotherapy, 2013-01, Vol.57 (1), p.664-667

2013

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Dipicolinic Acid Release by Germinating Clostridium difficile Spores Occurs through a Mechanosensing Mechanism

mSphere, 2016-11, Vol.1 (6)

2016

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Clostridioides difficile spore germination: initiation to DPA release

Current opinion in microbiology, 2022-02, Vol.65, p.101-107

2022

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Clostridium difficile spore biology: sporulation, germination, and spore structural proteins

Bile acid-independent protection against Clostridioides difficile infection

Inhibiting the Initiation of Clostridium difficile Spore Germination using Analogs of Chenodeoxycholic Acid, a Bile Acid

Bile acid recognition by the Clostridium difficile germinant receptor, CspC, is important for establishing infection

Bile Salts and Glycine as Cogerminants for Clostridium difficile Spores

The requirement for co-germinants during Clostridium difficile spore germination is influenced by mutations in yabG and cspA

Clostridioides difficile Biology: Sporulation, Germination, and Corresponding Therapies for C. difficile Infection

Hierarchical recognition of amino acid co-germinants during Clostridioides difficile spore germination

Gut associated metabolites and their roles in Clostridioides difficile pathogenesis

Spore Cortex Hydrolysis Precedes Dipicolinic Acid Release during Clostridium difficile Spore Germination

The small acid-soluble proteins of Clostridioides difficile are important for UV resistance and serve as a check point for sporulation

Using CRISPR-Cas9-mediated genome editing to generate C. difficile mutants defective in selenoproteins synthesis

Chenodeoxycholate Is an Inhibitor of Clostridium difficile Spore Germination

Metabolism of bile salts in mice influences spore germination in Clostridium difficile

Muricholic acids inhibit Clostridium difficile spore germination and growth

Reexamining the Germination Phenotypes of Several Clostridium difficile Strains Suggests Another Role for the CspC Germinant Receptor

Microbial Bile Acid Metabolic Clusters: The Bouncers at the Bar

Clostridioides difficile bile salt hydrolase activity has substrate specificity and affects biofilm formation

Conservation of the "Outside-in" Germination Pathway in Paraclostridium bifermentans

Identification of a Novel Lipoprotein Regulator of Clostridium difficile Spore Germination

Small molecule inhibitor of lipoteichoic acid synthesis is an antibiotic for Gram-positive bacteria

A sporulation signature protease is required for assembly of the spore surface layers, germination and host colonization in Clostridioides difficile

Both Fidaxomicin and Vancomycin Inhibit Outgrowth of Clostridium difficile Spores

Dipicolinic Acid Release by Germinating Clostridium difficile Spores Occurs through a Mechanosensing Mechanism

Clostridioides difficile spore germination: initiation to DPA release

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