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Structural basis for the selective activation of Rho GTPases by Dbl exchange factors

Nature structural & molecular biology, 2002-06, Vol.9 (6), p.468-475

2002

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GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors

Nature reviews. Molecular cell biology, 2005-02, Vol.6 (2), p.167-180

2005

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Regulation of phospholipase C isozymes by ras superfamily GTPases

Annual review of pharmacology and toxicology, 2006-01, Vol.46 (1), p.355-379

2006

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Pseudomonas syringae effector AvrRpt2 cleaves its C-terminally acylated target, RIN4, from Arabidopsis membranes to block RPM1 activation

Proceedings of the National Academy of Sciences - PNAS, 2005-05, Vol.102 (18), p.6496-6501

2005

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Tiam1 mediates Ras activation of Rac by a PI(3)K-independent mechanism

Nature cell biology, 2002-08, Vol.4 (8), p.621-625

2002

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The DH and PH Domains of Trio Coordinately Engage Rho GTPases for their Efficient Activation

Journal of molecular biology, 2007-05, Vol.368 (5), p.1307-1320

2007

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Phagocytosis of Apoptotic Cells Is Regulated by a UNC-73/TRIO-MIG-2/RhoG Signaling Module and Armadillo Repeats of CED-12/ELMO

Current biology, 2004-12, Vol.14 (24), p.2208-2216

2004

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Structural determinants for GoLoco-induced inhibition of nucleotide release by G α subunits

Nature (London), 2002-04, Vol.416 (6883), p.878-881

2002

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Crystal structure of Rac1 in complex with the guanine nucleotide exchange region of Tiam1

Nature (London), 2000-12, Vol.408 (6813), p.682-688

2000

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A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange

The EMBO journal, 2002-03, Vol.21 (6), p.1315-1326

2002

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A Steric-Inhibition Model for Regulation of Nucleotide Exchange via the Dock180 Family of GEFs

Current biology, 2005-02, Vol.15 (4), p.371-377

2005

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Crystal structure of a GA protein βγ dimer at 2.1Å resolution

Nature (London), 1996-01, Vol.379 (6563), p.369-374

1996

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Structural and Biochemical Characterization of CIB1 Delineates a New Family of EF-hand-containing Proteins

The Journal of biological chemistry, 2005-03, Vol.280 (9), p.8407-8415

2005

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Gγ-like (ggl) domains: new frontiers in g-protein signaling and β-propeller scaffolding

Biochemical pharmacology, 2001-06, Vol.61 (11), p.1329-1337

2001

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The 2.0 angstrom crystal structure of a heterotrimeric G protein

Nature (London), 1996-01, Vol.379 (6563), p.311-320

1996

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The 2.0 Å crystal structure of a heterotrimeric G protein

Nature (London), 1996-01, Vol.379 (6563), p.311-319

1996

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Tuba, a Novel Protein Containing Bin/Amphiphysin/Rvs and Dbl Homology Domains, Links Dynamin to Regulation of the Actin Cytoskeleton

The Journal of biological chemistry, 2003-12, Vol.278 (49), p.49031-49043

2003

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PH domain of ELMO functions in trans to regulate Rac activation via Dock180

Nature structural & molecular biology, 2004-08, Vol.11 (8), p.756-762

2004

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The α Aneurism: A Structural Motif Revealed in an Insertion Mutant of Staphylococcal Nuclease

Proceedings of the National Academy of Sciences - PNAS, 1993-04, Vol.90 (8), p.3275-3279

1993

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Direct Activation of Phospholipase C-ϵ by Rho

The Journal of biological chemistry, 2003-10, Vol.278 (42), p.41253-41258

2003

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Prediction of Protein-Protein Interfaces on G-Protein beta Subunits Reveals a Novel Phospholipase C beta 2 Binding Domain

Journal of molecular biology, 2009-10, Vol.392 (4), p.1044-1054

2009

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A General Strategy for Random Insertion and Substitution Mutagenesis: Substoichiometric Coupling of Trinucleotide Phosphoramidites

Proceedings of the National Academy of Sciences - PNAS, 1992-04, Vol.89 (8), p.3581-3585

1992

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Leukemia-associated Rho Guanine Nucleotide Exchange Factor, a Dbl Family Protein Found Mutated in Leukemia, Causes Transformation by Activation of RhoA

The Journal of biological chemistry, 2001-07, Vol.276 (29), p.27145-27151

2001

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Multifunctional Roles for the PH Domain of Dbs in Regulating Rho GTPase Activation

The Journal of biological chemistry, 2003-05, Vol.278 (20), p.18393-18400

2003

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The cystic fibrosis transmembrane conductance regulator. Effects of the most common cystic fibrosis-causing mutation on the secondary structure and stability of a synthetic peptide

The Journal of biological chemistry, 1992-03, Vol.267 (9), p.5727-5730

1992

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Structural basis for the selective activation of Rho GTPases by Dbl exchange factors

GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors

Regulation of phospholipase C isozymes by ras superfamily GTPases

Pseudomonas syringae effector AvrRpt2 cleaves its C-terminally acylated target, RIN4, from Arabidopsis membranes to block RPM1 activation

Tiam1 mediates Ras activation of Rac by a PI(3)K-independent mechanism

The DH and PH Domains of Trio Coordinately Engage Rho GTPases for their Efficient Activation

Phagocytosis of Apoptotic Cells Is Regulated by a UNC-73/TRIO-MIG-2/RhoG Signaling Module and Armadillo Repeats of CED-12/ELMO

Structural determinants for GoLoco-induced inhibition of nucleotide release by G α subunits

Crystal structure of Rac1 in complex with the guanine nucleotide exchange region of Tiam1

A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange

A Steric-Inhibition Model for Regulation of Nucleotide Exchange via the Dock180 Family of GEFs

Crystal structure of a GA protein βγ dimer at 2.1Å resolution

Structural and Biochemical Characterization of CIB1 Delineates a New Family of EF-hand-containing Proteins

Gγ-like (ggl) domains: new frontiers in g-protein signaling and β-propeller scaffolding

The 2.0 angstrom crystal structure of a heterotrimeric G protein

The 2.0 Å crystal structure of a heterotrimeric G protein

Tuba, a Novel Protein Containing Bin/Amphiphysin/Rvs and Dbl Homology Domains, Links Dynamin to Regulation of the Actin Cytoskeleton

PH domain of ELMO functions in trans to regulate Rac activation via Dock180

The α Aneurism: A Structural Motif Revealed in an Insertion Mutant of Staphylococcal Nuclease

Direct Activation of Phospholipase C-ϵ by Rho

Prediction of Protein-Protein Interfaces on G-Protein beta Subunits Reveals a Novel Phospholipase C beta 2 Binding Domain

A General Strategy for Random Insertion and Substitution Mutagenesis: Substoichiometric Coupling of Trinucleotide Phosphoramidites

Leukemia-associated Rho Guanine Nucleotide Exchange Factor, a Dbl Family Protein Found Mutated in Leukemia, Causes Transformation by Activation of RhoA

Multifunctional Roles for the PH Domain of Dbs in Regulating Rho GTPase Activation

The cystic fibrosis transmembrane conductance regulator. Effects of the most common cystic fibrosis-causing mutation on the secondary structure and stability of a synthetic peptide

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