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Repurposing Strategy of Atorvastatin against Trypanosoma cruzi: In Vitro Monotherapy and Combined Therapy with Benznidazole Exhibit Synergistic Trypanocidal Activity

Antimicrobial agents and chemotherapy, 2018-09, Vol.62 (9)

2018

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Antitrypanosomal Activity of Sterol 14α-Demethylase (CYP51) Inhibitors VNI and VFV in the Swiss Mouse Models of Chagas Disease Induced by the Trypanosoma cruzi Y Strain

Antimicrobial agents and chemotherapy, 2017-04, Vol.61 (4)

2017

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Cellular Effects of Reversed Amidines on Trypanosoma cruzi

Antimicrobial Agents and Chemotherapy, 2007-11, Vol.51 (11), p.3803-3809

2007

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The Trypanocidal Activity of Amidine Compounds Does Not Correlate with Their Binding Affinity to Trypanosoma cruzi Kinetoplast DNA

Antimicrobial Agents and Chemotherapy, 2011-10, Vol.55 (10), p.4765-4773

2011

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In Vitro and In Vivo Studies of the Trypanocidal Effect of Novel Quinolines

Antimicrobial agents and chemotherapy, 2018-02, Vol.62 (2)

2018

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Differential apoptosis-like cell death in amastigote and trypomastigote forms from Trypanosoma cruzi-infected heart cells in vitro

Cell and tissue research, 2010-07, Vol.341 (1), p.173-180

2010

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In Vitro and In Vivo Trypanosomicidal Action of Novel Arylimidamides against Trypanosoma cruzi

Antimicrobial agents and chemotherapy, 2016-04, Vol.60 (4), p.2425-2434

2016

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Phenotypic Screening In Vitro of Novel Aromatic Amidines against Trypanosoma cruzi

Antimicrobial agents and chemotherapy, 2016-08, Vol.60 (8), p.4701-4707

2016

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Novel amidines and analogues as promising agents against intracellular parasites: a systematic review

Parasitology, 2013-07, Vol.140 (8), p.929-951

2013

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Repurposing strategies for Chagas disease therapy: the effect of imatinib and derivatives against Trypanosoma cruzi

Parasitology, 2019-07, Vol.146 (8), p.1006-1012

2019

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Drug repurposing strategy against Trypanosoma cruzi infection: In vitro and in vivo assessment of the activity of metronidazole in mono- and combined therapy

Biochemical pharmacology, 2017-12, Vol.145, p.46-53

2017

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Biological, ultrastructural effect and subcellular localization of aromatic diamidines in Trypanosoma cruzi

Parasitology, 2010-02, Vol.137 (2), p.251-259

2010

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The potential of secondary metabolites from plants as drugs or leads against protozoan neglected diseases - part II

Current medicinal chemistry, 2012-05, Vol.19 (14), p.2176-2228

2012

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The potential of secondary metabolites from plants as drugs or leads against protozoan neglected diseases - part I

Current medicinal chemistry, 2012-05, Vol.19 (14), p.2128-2175

2012

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Trypanocidal activity and selectivity in vitro of aromatic amidine compounds upon bloodstream and intracellular forms of Trypanosoma cruzi

Experimental parasitology, 2011-02, Vol.127 (2), p.429-435

2011

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Trypanosoma cruzi: Alpha-2-macroglobulin regulates host cell apoptosis induced by the parasite infection in vitro

Experimental parasitology, 2008-03, Vol.118 (3), p.331-337

2008

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Antiparasitic activity of aromatic diamidines is related to apoptosis-like death in Trypanosoma cruzi

Parasitology, 2006-07, Vol.133 (1), p.75-79

2006

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In vitro investigation of the efficacy of novel diamidines against Trypanosoma cruzi

Parasitology, 2014-09, Vol.141 (10), p.1272-1276

2014

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Increased Trypanosoma cruzi Invasion and Heart Fibrosis Associated with High Transforming Growth Factor β Levels in Mice Deficient in α2-Macroglobulin

Infection and Immunity, 2002-09, Vol.70 (9), p.5115-5123

2002

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Aromatic diamidines as antiparasitic agents

Expert opinion on investigational drugs, 2005-08, Vol.14 (8), p.957-972

2005

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Phenyl substitution of furamidine markedly potentiates its anti-parasitic activity against Trypanosoma cruzi and Leishmania amazonensis

Biochemical pharmacology, 2004-08, Vol.68 (4), p.593-600

2004

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Host and parasite apoptosis following Trypanosoma cruzi infection in in vitro and in vivo models

Cell and tissue research, 2003-11, Vol.314 (2), p.223-235

2003

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Glycosylation patterns of human alpha2-macroglobulin: Analysis of lectin binding by electron microscopy

Micron (Oxford, England : 1993), 2010-08, Vol.41 (6), p.666-673

2010

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Activity of pyridyl-pyrazolone derivatives against Trypanosoma cruzi

Experimental parasitology, 2024-07, Vol.262, p.108787, Article 108787

2024

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Increased Trypanosoma cruzi invasion and heart fibrosis associated with high transforming growth factor beta levels in mice deficient in alpha(2)-macroglobulin

Infection and immunity, 2002-09, Vol.70 (9), p.5115-5123

2002

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Repurposing Strategy of Atorvastatin against Trypanosoma cruzi: In Vitro Monotherapy and Combined Therapy with Benznidazole Exhibit Synergistic Trypanocidal Activity

Antitrypanosomal Activity of Sterol 14α-Demethylase (CYP51) Inhibitors VNI and VFV in the Swiss Mouse Models of Chagas Disease Induced by the Trypanosoma cruzi Y Strain

Cellular Effects of Reversed Amidines on Trypanosoma cruzi

The Trypanocidal Activity of Amidine Compounds Does Not Correlate with Their Binding Affinity to Trypanosoma cruzi Kinetoplast DNA

In Vitro and In Vivo Studies of the Trypanocidal Effect of Novel Quinolines

Differential apoptosis-like cell death in amastigote and trypomastigote forms from Trypanosoma cruzi-infected heart cells in vitro

In Vitro and In Vivo Trypanosomicidal Action of Novel Arylimidamides against Trypanosoma cruzi

Phenotypic Screening In Vitro of Novel Aromatic Amidines against Trypanosoma cruzi

Novel amidines and analogues as promising agents against intracellular parasites: a systematic review

Repurposing strategies for Chagas disease therapy: the effect of imatinib and derivatives against Trypanosoma cruzi

Drug repurposing strategy against Trypanosoma cruzi infection: In vitro and in vivo assessment of the activity of metronidazole in mono- and combined therapy

Biological, ultrastructural effect and subcellular localization of aromatic diamidines in Trypanosoma cruzi

The potential of secondary metabolites from plants as drugs or leads against protozoan neglected diseases - part II

The potential of secondary metabolites from plants as drugs or leads against protozoan neglected diseases - part I

Trypanocidal activity and selectivity in vitro of aromatic amidine compounds upon bloodstream and intracellular forms of Trypanosoma cruzi

Trypanosoma cruzi: Alpha-2-macroglobulin regulates host cell apoptosis induced by the parasite infection in vitro

Antiparasitic activity of aromatic diamidines is related to apoptosis-like death in Trypanosoma cruzi

In vitro investigation of the efficacy of novel diamidines against Trypanosoma cruzi

Increased Trypanosoma cruzi Invasion and Heart Fibrosis Associated with High Transforming Growth Factor β Levels in Mice Deficient in α2-Macroglobulin

Aromatic diamidines as antiparasitic agents

Phenyl substitution of furamidine markedly potentiates its anti-parasitic activity against Trypanosoma cruzi and Leishmania amazonensis

Host and parasite apoptosis following Trypanosoma cruzi infection in in vitro and in vivo models

Glycosylation patterns of human alpha2-macroglobulin: Analysis of lectin binding by electron microscopy

Activity of pyridyl-pyrazolone derivatives against Trypanosoma cruzi

Increased Trypanosoma cruzi invasion and heart fibrosis associated with high transforming growth factor beta levels in mice deficient in alpha(2)-macroglobulin

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