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Toward a Consensus on Applying Quantitative Liquid Chromatography‐Tandem Mass Spectrometry Proteomics in Translational Pharmacology Research: A White Paper

Clinical pharmacology and therapeutics, 2019-09, Vol.106 (3), p.525-543

2019

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Quantification of Four Efflux Drug Transporters in Liver and Kidney Across Species Using Targeted Quantitative Proteomics by Isotope Dilution NanoLC-MS/MS

Pharmaceutical research, 2016-09, Vol.33 (9), p.2280-2288

2016

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Quantification of Human Uridine-Diphosphate Glucuronosyl Transferase 1A Isoforms in Liver, Intestine, and Kidney Using Nanobore Liquid Chromatography–Tandem Mass Spectrometry

Analytical chemistry (Washington), 2012-01, Vol.84 (1), p.98-105

2012

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Quantitative profiling of human renal UDP-glucuronosyltransferases and glucuronidation activity: a comparison of normal and tumoral kidney tissues

Drug metabolism and disposition, 2015-04, Vol.43 (4), p.611-619

2015

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Pharmacokinetics of Organic Cation Transporter 1 (OCT1) Substrates in Oct1/2 Knockout Mice and Species Difference in Hepatic OCT1-Mediated Uptake

Drug metabolism and disposition, 2020-02, Vol.48 (2), p.93-105

2020

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Developmental Expression of the Cytosolic Sulfotransferases in Human Liver

Drug metabolism and disposition, 2019-06, Vol.47 (6), p.592-600

2019

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Scaling factors for the in vitro–in vivo extrapolation (IV–IVE) of renal drug and xenobiotic glucuronidation clearance

British journal of clinical pharmacology, 2016-06, Vol.81 (6), p.1153-1164

2016

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Quantification of membrane transporter proteins in human lung and immortalized cell lines using targeted quantitative proteomic analysis by isotope dilution nanoLC–MS/MS

Journal of pharmaceutical and biomedical analysis, 2018-05, Vol.154, p.150-157

2018

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Pregnancy related hormones increase CYP3A mediated buprenorphine metabolism in human hepatocytes: a comparison to CYP3A substrates nifedipine and midazolam

Frontiers in pharmacology, 2023-07, Vol.14, p.1218703

2023

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Formation of CYP3A‐specific metabolites of ibrutinib in vitro is correlated with hepatic CYP3A activity and 4β‐hydroxycholesterol/cholesterol ratio

Clinical and translational science, 2023-02, Vol.16 (2), p.279-291

2023

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Evaluation of human primary intestinal monolayers for drug metabolizing capabilities

Journal of biological engineering, 2019-11, Vol.13 (1), p.82-15, Article 82

2019

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Impact of pregnancy related hormones on drug metabolizing enzyme and transport protein concentrations in human hepatocytes

Frontiers in pharmacology, 2022-09, Vol.13, p.1004010

2022

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Pharmacokinetics and metabolic profile of free, conjugated, and total silymarin flavonolignans in human plasma after oral administration of milk thistle extract

Drug metabolism and disposition, 2008-01, Vol.36 (1), p.65-72

2008

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Pregnancy-Related Hormones Increase UGT1A1-Mediated Labetalol Metabolism in Human Hepatocytes

Frontiers in pharmacology, 2021-04, Vol.12, p.655320

2021

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Molecular transport through primary human small intestinal monolayers by culture on a collagen scaffold with a gradient of chemical cross-linking

Journal of biological engineering, 2019-04, Vol.13 (1), p.36-15, Article 36

2019

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A phase I evaluation of the effect of curcumin on dose‐limiting toxicity and pharmacokinetics of irinotecan in participants with solid tumors

Clinical and translational science, 2022-05, Vol.15 (5), p.1304-1315

2022

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Expansion of Knowledge on OCT1 Variant Activity In Vitro and In Vivo Using Oct1/2 -/- Mice

Frontiers in pharmacology, 2021-02, Vol.12, p.631793

2021

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Extracellular Vesicles as Drug Delivery System for the Treatment of Neurodegenerative Disorders: Optimization of the Cell Source

Advanced NanoBiomed Research (Online), 2021-12, Vol.1 (12), p.n/a

2021

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Extracellular Vesicles as Drug Delivery System for the Treatment of Neurodegenerative Disorders: Optimization of the Cell Source

Advanced NanoBiomed Research (Online), 2023-06, Vol.3 (6), p.n/a

2023

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Glucuronidation and covalent protein binding of benoxaprofen and flunoxaprofen in sandwich-cultured rat and human hepatocytes

Drug metabolism and disposition, 2009-12, Vol.37 (12), p.2314-2322

2009

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Using Extracellular Vesicles Released by GDNF-Transfected Macrophages for Therapy of Parkinson Disease

Cells (Basel, Switzerland), 2022-06, Vol.11 (12), p.1933

2022

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The pharmacokinetics of silymarin is altered in patients with hepatitis C virus and nonalcoholic Fatty liver disease and correlates with plasma caspase-3/7 activity

Drug metabolism and disposition, 2008-09, Vol.36 (9), p.1909-1916

2008

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UDP-glucuronosyltransferase 1A1 is the principal enzyme responsible for etoposide glucuronidation in human liver and intestinal microsomes: structural characterization of phenolic and alcoholic glucuronides of etoposide and estimation of enzyme kinetics

Drug metabolism and disposition, 2007-03, Vol.35 (3), p.371-380

2007

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John R. Brinkley: A Quintessential American Quack

Journal of community hospital internal medicine perspectives, 2022-09, Vol.12 (5), p.1-5

Smith, Philip C.

2022

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Safety and Pharmacokinetics of Bevirimat (PA-457), a Novel Inhibitor of Human Immunodeficiency Virus Maturation, in Healthy Volunteers

Antimicrobial Agents and Chemotherapy, 2007-09, Vol.51 (9), p.3063-3066

2007

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Toward a Consensus on Applying Quantitative Liquid Chromatography‐Tandem Mass Spectrometry Proteomics in Translational Pharmacology Research: A White Paper

Quantification of Four Efflux Drug Transporters in Liver and Kidney Across Species Using Targeted Quantitative Proteomics by Isotope Dilution NanoLC-MS/MS

Quantification of Human Uridine-Diphosphate Glucuronosyl Transferase 1A Isoforms in Liver, Intestine, and Kidney Using Nanobore Liquid Chromatography–Tandem Mass Spectrometry

Quantitative profiling of human renal UDP-glucuronosyltransferases and glucuronidation activity: a comparison of normal and tumoral kidney tissues

Pharmacokinetics of Organic Cation Transporter 1 (OCT1) Substrates in Oct1/2 Knockout Mice and Species Difference in Hepatic OCT1-Mediated Uptake

Developmental Expression of the Cytosolic Sulfotransferases in Human Liver

Scaling factors for the in vitro–in vivo extrapolation (IV–IVE) of renal drug and xenobiotic glucuronidation clearance

Quantification of membrane transporter proteins in human lung and immortalized cell lines using targeted quantitative proteomic analysis by isotope dilution nanoLC–MS/MS

Pregnancy related hormones increase CYP3A mediated buprenorphine metabolism in human hepatocytes: a comparison to CYP3A substrates nifedipine and midazolam

Formation of CYP3A‐specific metabolites of ibrutinib in vitro is correlated with hepatic CYP3A activity and 4β‐hydroxycholesterol/cholesterol ratio

Evaluation of human primary intestinal monolayers for drug metabolizing capabilities

Impact of pregnancy related hormones on drug metabolizing enzyme and transport protein concentrations in human hepatocytes

Pharmacokinetics and metabolic profile of free, conjugated, and total silymarin flavonolignans in human plasma after oral administration of milk thistle extract

Pregnancy-Related Hormones Increase UGT1A1-Mediated Labetalol Metabolism in Human Hepatocytes

Molecular transport through primary human small intestinal monolayers by culture on a collagen scaffold with a gradient of chemical cross-linking

A phase I evaluation of the effect of curcumin on dose‐limiting toxicity and pharmacokinetics of irinotecan in participants with solid tumors

Expansion of Knowledge on OCT1 Variant Activity In Vitro and In Vivo Using Oct1/2 -/- Mice

Extracellular Vesicles as Drug Delivery System for the Treatment of Neurodegenerative Disorders: Optimization of the Cell Source

Extracellular Vesicles as Drug Delivery System for the Treatment of Neurodegenerative Disorders: Optimization of the Cell Source

Glucuronidation and covalent protein binding of benoxaprofen and flunoxaprofen in sandwich-cultured rat and human hepatocytes

Using Extracellular Vesicles Released by GDNF-Transfected Macrophages for Therapy of Parkinson Disease

The pharmacokinetics of silymarin is altered in patients with hepatitis C virus and nonalcoholic Fatty liver disease and correlates with plasma caspase-3/7 activity

UDP-glucuronosyltransferase 1A1 is the principal enzyme responsible for etoposide glucuronidation in human liver and intestinal microsomes: structural characterization of phenolic and alcoholic glucuronides of etoposide and estimation of enzyme kinetics

John R. Brinkley: A Quintessential American Quack

Safety and Pharmacokinetics of Bevirimat (PA-457), a Novel Inhibitor of Human Immunodeficiency Virus Maturation, in Healthy Volunteers

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